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3 votes
2 answers
149 views

Why isn’t porphyria treated with ferrochelatase supplementation?

Erythropoietic protoporphyria is a disorder characterized by ferrochelatase enzyme deficiency in all tissues. Ferrochelatase puts the iron in protoporphyrin to make haem. Other enzyme deficiencies ...
Furrier Transform's user avatar
-1 votes
2 answers
149 views

Does nitroglycerin have any medicinal effect other than pain relief?

People with recent heart attacks etc. are prescribed sub-lingual nitroglycerin spray for emergency use when experiencing chest pain. Does the treatment have any other useful medicinal effect? If not, ...
Ray Butterworth's user avatar
0 votes
0 answers
15 views

What role do studies say that "rest" plays in tennis elbow healing?

I was recently diagnosed with tennis elbow and the ortho ordered 'rest' and NSAIDS. Limited (programming) work, and no more gaming or cards, and only necessary phone usage, as well as no heavy labor ...
Nicholas's user avatar
  • 131
-1 votes
1 answer
63 views

Are treatments for (hyper/hypo)parathyroidism mutually exclusive from treatmeants to (hyper/hypo)calcemia?

Summarized in the table below the drugs that were listed in my professor's lecture slides for the treatment of Hyperparathyroidism (first column) and hypoparathyroidism (second column) Are treatments ...
Doe Pull's user avatar
0 votes
0 answers
37 views

Towards safer chemotherapy: What is the current state of cancer therapy using targeted drug-delivery?

I work in the biophysics of making non-viral drug-delivery vectors, which can encapsulate the drug molecules and release the drugs at targeted sites. The release mechanism at targeted sites are ...
user35952's user avatar
  • 101
1 vote
0 answers
29 views

Is benzoyl peroxide discredited?

For years I was able to get three main kinds of acne treatment creams: salicylic acid, benzoyl peroxide, and random herbal extracts of questionably effectiveness. Earlier this year, the benzoyl ...
Luke Sawczak's user avatar
1 vote
0 answers
29 views

What's the success rate of Imiquimod Cream 5% recommended for the treatment of facial superficial basal cell carcinoma beyond 5 years post-treatment?

I have read several studies on the success rate of Imiquimod Cream 5% for the treatment of facial superficial basal cell carcinoma, however none of them looked at beyond 5 years post-treatment. E.g. {...
Franck Dernoncourt's user avatar
2 votes
0 answers
30 views

What is the difference in cosmesis of the treatment of a seborrheic keratosis between cryotherapy and electrodesiccation?

There exist different treatments to remove a seborrheic keratosis (SK), such as cryotherapy and electrodesiccation {1}. I wonder what the difference in cosmesis of the treatment of a seborrheic ...
Franck Dernoncourt's user avatar
0 votes
0 answers
23 views

Does ingesting itraconazole pills increase the likelihood of success for a topical cream (Imiquimod/5-Fluorouracil) to treat BCC?

The 2014 phase II trial {1} indicates that oral itraconazole is beneficial for the treatment of basal cell carcinoma (BCC). Imiquimod 5% cream and topical 5-Fluorouracil (5-FU) have also been used to ...
Franck Dernoncourt's user avatar
1 vote
1 answer
50 views

Does any drug/cream help prevent DNA damage post UV exposure?

I read on https://medicine.yale.edu/news-article/sun-damage-occurs-even-after-sunset/: When UV light hits the skin , it causes a type of DNA damage known as a cyclobutanepyrimidinedimer (CPD) , in ...
Franck Dernoncourt's user avatar
1 vote
0 answers
16 views

What treatments help decrease the percentage of immature type III collagen fibers following a tendon injury?

{1} mentions: A microscopic view of tendinosis reveals an increase of immature type III collagen fibers (mature type I fibers dominate in healthy tendon tissue). What treatments help decrease the ...
Franck Dernoncourt's user avatar
1 vote
0 answers
42 views

Is there a good recent review on the treatment options for COVID19?

I am looking for a summary/review of all the treatment options that have been studied for COVID19? The British medical journal is updating a tremendously helpful ressource (https://doi.org/10.1136/bmj....
MonsieurWave's user avatar
2 votes
1 answer
102 views

Why is sepsis more common with leukemia than with cancers involving physical tumors?

Does it have something to do with differences between leukemia versus other cancers, or differences between the treatments of leukemia versus other cancers? Quote from the source: People with cancers ...
A. Kvåle's user avatar
  • 135
1 vote
1 answer
31 views

How can an individual seek to get an idea investigated as a potential treatment, or seek a change in a particular guideline?

It would be dangerous for the general public to provide advice on 'what they reckon' would be a good treatment or a good guideline for medical advice; and that has clearly caused problems in the past. ...
atreeon's user avatar
  • 109
0 votes
0 answers
76 views

How is a ruptured blood vessel repaired? (Drew Bledsoe)

A famous near-fatal injury is the ruptured blood vessel suffered by Drew Bledsoe in a football game in 2001. He was hit in the chest by the tackler's shoulder and this sheared a blood vessel in his ...
Tyler Durden's user avatar
1 vote
0 answers
45 views

How much do certain probiotics reduce cavity causing bacteria?

In the paper titled Effect of Short-term Consumption of Amul Probiotic Yogurt Containing Lactobacillus acidophilus La5 and Bifidobacterium Lactis Bb12 on Salivary Streptococcus mutans Count in High ...
hippypink's user avatar
-1 votes
1 answer
30 views

Is their terminology for varying bone fracture severity?

I have done research on the various different types of bone fractures however I am not able to find any resources discussing specifically the severity of fractures. For example I had assumed that the ...
FrontEnd's user avatar
  • 109
0 votes
0 answers
29 views

How long is the delay when rehydrating orally vs. IV?

The going recommendation for patients who present to the emergency room with dehydration is IV fluids. It seems to me that this is fairly wasteful and needlessly expensive. Is rehydrating with a ...
TheEnvironmentalist's user avatar
2 votes
1 answer
86 views

What is the difference in cosmesis of the treatment of a seborrheic keratosis between cryotherapy and curettage?

There exist different treatments to remove a seborrheic keratosis, such as cryotherapy and curettage+electrodesiccation {2,3}. I wonder what the difference in cosmesis of the treatment of a seborrheic ...
Franck Dernoncourt's user avatar
0 votes
0 answers
58 views

Why isn't Imiquimod Cream 5% recommended for the treatment of superficial basal cell carcinoma located on the face?

I read on Approval Package for Imiquimod Cream, 5% on February 25, 2010 (mirror): Reference Drug (NDA number): Aldara® (imiquimod) 5% Cream (NDA 20-723), Graceway Pharmaceuticals. Date of approval: 2/...
Franck Dernoncourt's user avatar
0 votes
0 answers
28 views

Should Imiquimod 5% cream be applied 1 cm beyond the target tumor when treating a facial basal cell carcinoma, and if so, why?

I read on https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20723s016lbl.pdf (mirror): 364 patients with primary superficial basal cell carcinoma (sBCC) were treated with Aldara Cream or ...
Franck Dernoncourt's user avatar
-2 votes
1 answer
133 views

What is the success rate of topical imiquimod 5% cream to treat infiltrative basal cell carcinoma (BCC)?

What is the success rate of topical imiquimod 5% cream (US brand: Aldara) to treat infiltrative basal cell carcinoma (BCC)? So far I've only found some case study {1} and some study on using topical ...
Franck Dernoncourt's user avatar
0 votes
1 answer
88 views

Is Imiquimod 5% cream (US brand: Aldara) helpful as an adjunctive treatment of a facial basal cell carcinoma (BCC) prior to a Mohs surgery?

I wonder whether Imiquimod 5% cream (US brand: Aldara) is not helpful as an adjunctive treatment of a facial basal cell carcinoma (BCC) prior to a Mohs surgery. Helpful in this context means 1) ...
Franck Dernoncourt's user avatar
0 votes
1 answer
98 views

How effective is topical fluorouracil to treat facial superficial basal cell carcinoma (BCC)?

I wonder how effective topical fluorouracil is to treat facial superficial basal cell carcinoma (BCC). What I have found so far doesn't give any source supporting their claims or I cannot access them: ...
Franck Dernoncourt's user avatar
2 votes
0 answers
52 views

Symptoms in men and women

I was reading something about women’s heart attacks and how they are more likely to die from them as doctors are usually taught male symptoms in unis or something. I tried finding something about it ...
J.Wayne's user avatar
  • 121
1 vote
0 answers
29 views

Can IVIG treatment increase risk of infections?

Intravenous Immunoglobulins (IVIG) are often used to treat patients with impaired antibody production or autoimmune conditions[1]. However, according to this paper[2], it can also inhibit antibody ...
D.Tan's user avatar
  • 1,124
3 votes
3 answers
99 views

Do these diagrams have an official name (treatment plan, treatment schedule, protocol)

I am doing research on treatment plans and protocols in order to design software to minimize error when indicating medicine, procedures, exams, etc. We also want to monitor treatment and somehow ...
supercoco's user avatar
  • 131
3 votes
1 answer
64 views

Is stem cells treatment an effective cure for nerve damage from peripheral neuropathy in DM?

Is stem cells treatment an effective cure for nerve damage from peripheral neuropathy in DM? Googling returns plenty of hits. Top results are businesses offering stem cells treatment for almost any ...
user3125486's user avatar
3 votes
1 answer
64 views

How effective is eucalyptus-based treatment for curing COVID-19 (or coronavirus in general)?

According to The Jakarta Post, (Indonesia's) Agriculture Ministry claims to have developed eucalyptus-based COVID-19 treatment: The Agriculture Ministry has developed a eucalyptus-based treatment ...
Andrew T.'s user avatar
  • 139
6 votes
1 answer
210 views

Why are antibodies not used as treatments for infectious diseases?

It seems like human monoclonal antibodies would be the ideal treatment for any serious infectious disease. Unlike vaccines, they don't depend on having the immune system recognize the right epitope, ...
Alex I's user avatar
  • 64
3 votes
1 answer
85 views

Why can't simple blood transfusions be used for treatment of COVID-19, instead of plasma transfusions? [closed]

It has been recently been shown that convalescent plasma from previously infected patients can be used to help others gain immunity against the disease. But why do we need to use plasma for this ...
JonathanReez's user avatar
  • 1,496
0 votes
0 answers
57 views

Conflicting opinions on treatment of COVID-19 shortness of breath

There are two authoritative conflicting opinions on treatment of COVID-19 shortness of breath that came from physicians in the front-lines last week. David Price, MD said there's no need to go to a ...
stretch's user avatar
  • 101
4 votes
1 answer
47 views

What is the rationale behind using Il-6 inhibitors to treat COVID-19 patients?

According to the Infectious Disease Society of America (IDSA), one of the possible treatment options for COVID-19 patients is il-6 inhibitors (tocilizumab, sarilumab). What is the rationale behind ...
D.Tan's user avatar
  • 1,124
4 votes
2 answers
245 views

Safety data on chloroquine?

Prominent politicians in the USA have been calling for the use of both Chloroquine and Hydroxychloroquine in the management of Covid-19. Day after day, the salesman turned president has encouraged ...
Graham Chiu's user avatar
  • 13.3k
1 vote
2 answers
126 views

What are the special medications to treat Covid-19?

We know there is no cure for Covid-19 (currently) and the treatment focuses on managing symptoms as the virus runs its course. The main symptoms of Covid-19 are -Fever -Cough -Shortness of breath ...
I likeThatMeow's user avatar
0 votes
1 answer
77 views

When could chloroquine and hydroxychloroquine be widely available for Covid-19 treatment? [closed]

According to this article, chloroquine and hydroxychloroquine could be effective treatments for Covid-19. Assuming the drugs are well tolerated in clinical trials and seem effective at treating ...
Stevie Mahoney's user avatar
1 vote
0 answers
26 views

Is it possible, and what would be required to modify a ventilator to support two patients concurrently?

An article from a pediatrician on NYT suggested this as a possibility, I'm keen to know if it could be done in an emergency/shortage situation. If so: What would the challenges be from a mechanical/...
user3772748's user avatar
1 vote
1 answer
23 views

Neuronal ceroid lipofuscinosis treatments [closed]

Could Batten’s disease be cured by supplementing a drug which promotes lipolysis, since it is caused by an accumulation of lipids in brain?
Vyshakh 's user avatar
2 votes
0 answers
22 views

Does treatment with pyrimethamine and sulfadiazine eliminate reservoirs of Toxoplasma gondii?

Toxoplasma gondii is known to be one of many pathogens that sequesters away in nerve cells, as well as cysts in the muscles and liver, to avoid the immune system. Standard treatment for severe ...
Tal's user avatar
  • 181
1 vote
2 answers
183 views

Can myopia be treated by applying pressure?

I have high myopia in my right eye (~7.00). I've noticed that unsystematically applying pressure onto certain areas of the eyelid onto the eye can actually bring the power down to about 3-5.00 (by ...
user avatar
1 vote
2 answers
1k views

Does cissus quadrangularis help prevent or heal a tendinopathy?

I have seen many non-scientific claims that cissus quadrangularis help heal a tendinopathy. For example: https://www.resonatenutrition.com/cissus_quadrangulairs_joint_repair.html (mirror): Today ...
Franck Dernoncourt's user avatar
4 votes
1 answer
150 views

Does astaxanthin help prevent or heal a tendinopathy?

{1} claims that astaxanthin: Use of natural astaxanthin may suggest that daily use can help alleviate pain associated with Tennis Elbow, and increase mobility This study doesn't seem to have ...
Franck Dernoncourt's user avatar
1 vote
1 answer
38 views

Mortality and when a protocol becomes statistically significant [closed]

A study has a placebo given to one group, GROUP P, and a medication given to another group, GROUP M. This medication could be given to prevent colon cancer, anemia, or any other ailment that may ...
paulj's user avatar
  • 173
1 vote
0 answers
27 views

Does the delivery of BMP-12,-13,-14 (either in form of a gene or a protein) into an injured tendon help improve healing in humans?

I have read that delivery of BMP-12,-13,-14 (either in form of a gene or a protein) into an injured tendon improved healing, but I haven't been able yet to find an in-vivo study in humans confirming ...
Franck Dernoncourt's user avatar
0 votes
1 answer
45 views

Is it possible to immunize against bacteria?

In anticipation of going to a region with known prevalence of flesh eating bacteria, can an individual take antibiotics prior to going to prevent it from being contracted? https://www.cnn.com/2019/07/...
Muze's user avatar
  • 1
2 votes
1 answer
126 views

How to calculate my "approximate" mortality rate while in ICU?

To make a long story as short as possible for context, I was rushed to the ER while in cardiac arrest back in 2014. Heart stopped beating momentarily and lost oxygen to the part of my brain. None of ...
Noah Roth's user avatar