Questions tagged [covid-19]

Describes the clinical disease caused by the SARS-CoV-2 virus

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Is it possible to increase viral load and COVID-19 disease severity through subsequent infectious doses?

There is potentially a causal chain leading from high initial infectious dose to high viral load to high disease severity for COVID-19. See, for example, evidence surveyed here. However, once someone ...
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What strategies are there to eradicate covid 19 completely?

I am wondering why (at least in Germany where I am living) nobody seems to discuss the option to search for strategies to eradicate Covid 19 completely in particular without relying completely on a ...
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Can Ventilator ACM812a be used for COVID-19 infected? [closed]

This is a simple question. Can Chinese Ventilator ACM812a be used for COVID-19 infected as it's quite unclear when reading the specification and its parameters? Especially this line in specification: ...
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Why do we seemingly not know how COVID will behave during winter, when it was winter in much of the world?

(Not sure if this is the right SE for this question) Why COVID Outbreaks Could Worsen This Winter Baker has tried to tease apart the effect of climate on the seasonal pattern of cases during the ...
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Do having multiple COVID tests decrease the chance of a false negative?

With my work we're required to get frequent COVID tests. Sometimes it happens we get COVID tested twice before the first day of work. So for example if I'm working Saturday I may get tested the ...
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What do these terminologies and values in a PCR report mean?

My PCR report contains my personal information and the following information. I want to understand what the values and terminologies mean. SARS-CoV-2 by Real-Time RT-PCR ASSAY (Nucleic Acid ...
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Antibodies compared to Remdesivir [closed]

I have contracted covid-19 before and I also "fractured / broke" two toes simultaneously while skateboarding later. Thus I have antibodies and the like, so I was thinking is Remdesivir ...
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UK - Sweden Covid-19 Comparison

I compared Covid-19 data on the 17th of October 2020, using this source: https://coronavirus.jhu.edu/map.html UK population = 66650000 Uk cases = 708297 UK deaths = 43669 66650000 / 708297 = 1 ...
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Why the mismatch between the EUROMOMO mortality rate and 'COVID-19 second wave' positive tests and hospitalizations?

Currently (September/October 2020) there is a large increase in the percentage of COVID-19 tests that come out positive, at least in several countries in Europe. And, at least in the Netherlands, ...
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For how long can you wear a surgical mask? [closed]

I used to think that you can wear a mask for up to two hours, regardless of how many times you put it on and take it off. This guide says you can wear it for up to five times without any ...
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What should you put on your face if you want to protect both yourself and others?

Surgical masks protect other people but provide almost no protection for the wearer. Respirators (with valves) protect the wearer but don't protect those around you. What should you put on your face ...
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How effective are reused surgical masks?

Let's say I have used a surgical mask multiple times. And say I left it on a safe place, untouched, for three days which is the longest that viable SARS-CoV-2 has been found on different materials (...
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RNA vaccination and autoimmune reactions

to my knowledge we do not have any robust experience with RNA vaccination. Most likely this will change in the near future as RNA vaccines against COVID are in the pipline. The rational behind this ...
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What does “pause” mean in Covid19 Vaccine Clinical Trials?

Johnson and Johnson as well as Astra Zeneca recently announced that they were going to "pause" in their respective clinical trials for a Covid19 vaccine. What exactly are they "pausing&...
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Are lockdowns good or bad? What is the scientific consensus, if any? [closed]

I thought doctors support lockdown measures and populist politicians oppose them, but then this "Barrington Declaration" cropped up and I don't know what to think now. Are lockdowns good or ...
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How/when can a doctor say that someone will no longer transmit Covid?

Source This may sound like yet another anti-trump post, but, really I am more concerned for my own health, and that of my family. He is just an easily accessible example (feel free to migrate this to ...
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How did WHO estimate the number of suspected worldwide COVID-19 cases?

A couple of days ago World Health Organization said that around 780 million people worldwide (or one in ten people worldwide) are suspected to have had COVID-19. (One in 10 worldwide may have had ...
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Is it assumed that COVID-19 vaccine will prevent you from infecting others?

My question is quite short. I tried to find an answer anywhere, but for some reason nobody asked it before. There are many countries which are developing vaccines from COVID-19. The good vaccine will ...
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Why aren't lung machines / ECMO widely used for COVID-19?

I am not a doctor but I have read quite a bit on how COVID-19 affects the body. The ability of a critically afflicted patient to efficiently exchange oxygen drops off a cliff as the lungs fill with a ...
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Is there a simple plot comparing covid lethality to flu as a function of age?

There is so much arguing over covid-19 vs. influenza. I would like to have some solid data in my hands. Can anyone point to a simple graph of the following? age vs. either CFR or IFR with one line for ...
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Are there known outdoor super spreader events for COVID-19? Are there *any* known outdoor infections at all?

The title says it all: Are there known outdoor events or gatherings where the virus was spread to a large number of persons? We know of many indoor super spreader events (choirs, bars, private parties ...
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What is the definition and significance of administration of “Compassionate Use Drug”?

There seems to be some conflict about the use of "Compassionate Drug Authorizations". Does the request and use of such a drug indicate that a patient is in extreme danger? Barkground: The ...
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why isn't this finger stick antibody test (for covid) in more common use?

I had some concerns about going to the dentist, because dental treatment involves a lot of aerosolized droplets and seems like a good way to get a high dose of covid. My dentist's office (in Manhattan)...
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How come moderna vaccine can last at much more much higher temperature than Pfizer's vaccine?

I've read recently that Moderna's vaccine for covid-19 can last at around 60 degree more than Pfizer's. My question is why, given that they both use the same technique? references: https://...
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Is the efficacy of N95 respirators or surgical masks reduced when wet (COVID-19)?

If my face mask gets wet, is its efficacy in preventing the spread of coronavirus diminished? If so, how much? It's monsoon season here in India, and my method of transportation (safer than crowded ...
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Are COVID-19 patients infectious even if test results are negative?

With Covid-19, are people infectious in the first days after infection before they test positive on a Covid test? I have learned that Covid-19 tests are ineffective in the first few days after being ...
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Do oxygen and carbon dioxide move with Brownian motion? And, if so, do they get trapped by N95 masks?

Do oxygen and carbon dioxide move with brownian motion? And, if so, do they get trapped by N95 masks? Health professionals are experts agree: we should be wearing masks all day when in public during ...
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Why does the WHO's definition of respiratory droplets encompass such small diameters?

I frequently hear the World Health Organization (WHO) identify diameters of 5-10 μm as the size cutoff between "respiratory dropletes" and "droplet nuclei". For example, in a ...
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Why Pakistan can “flatten the curve” but India can't?

Comparing the Covid 19 trends between India and Pakistan: One can immediately notice the stark difference: Pakistan managed to "flatten the curve", and India is unable to control the ...
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Do comorbidities that have an important negative impact for COVID-19 patients are generally affecting patients with viral infections?

I have often seen in media about the comorbidities that make things worse for a COVID-19 patient. The most often mentioned are hypertension and diabetes as also mentioned in this article: From what ...
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Estimated deaths if Covid control is based on herd immunity

Rachael Maddow suggested on her 9/16/20 show that reliance on herd immunity (naturally acquired immunity) to control the continued spread of COVID-19 could result in the death of 2 to 6 million ...
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Why COVID-19 “immunogenicity may be 70%”?

The USA CDC director Dr. Robert Redfield was recently quoted in the media as saying: "I might even go so far as to say that this face mask is more guaranteed to protect me against Covid than ...
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Which websites can be regarded as reliable sources of information for current treatment guidelines for COVID-19?

I usually get my updates from the dedicated website of the NIH (link), but this is probably not the only source, and I want to be as up-to-date as I can, so I need to know where to look. There are ...
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How many variations of coronavirus are there and how can a vaccine address all of them?

I have read that there are 7 types of coronavirus disease. I have also heard that there are more than 3000 variations of this disease. How much variations are there? Also, how can a vaccine address ...
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COVID19 Vaccine Clinical Trials

I am interested in learning about the details of the Phase 3 clinical trial designs for the Moderna, Pfizer/Biotech, and AstraZeneca/Oxford vaccines. I expect that the trial designs would be published ...
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Was Australia successful in reducing the Covid-19 cases in the Melbourne towers, following the “hard lockdown”?

The BBC reported in July that 3,000 people in low-income public housing were put in "hard lockdown" in Melbourne (10 zip codes and/or nine tower blocks), meaning their inhabitants were not ...
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Is it true that half of the COVID-19 patients, even seemingly without symptoms, obtain serious heart damage?

In this video, complex systems expert and physicist-turned-epidemiologist Yaneer Bar-Yam claims that according to recent findings, about half of the people that have been infected with COVID-19 will ...
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What happened to Solidarity?

Solidarity is a large clinical trial of treatment candidates for COVID–19, organised by the World Health Organisation (WHO). The relevant page on the WHO website—last updated on July 6, 2020—says: The ...
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Why hasn't Russia's daily COVID-19 cases decreased as a result of its vaccine?

On August 11, Russian president Vladimir Putin announced a new vaccine for COVID-19. Since then Russia's COVID charts have looked like this: Evidently the vaccine has had a weak-to-no effect on both ...
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Does being outdoors but in close proximity to someone make a difference in Covid-19 transmission?

In a recent news article I've read that Outdoor haircuts were allowed in California from Tuesday, under new rules announced by the mayor, but indoor salons remain shut. Is this kind of rule/...
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Level of vaccination for safe, large, international event [closed]

I've read as much as I've been able about COVID-19 all these months, but nothing comes to mind that talks about what an appropriate level of vaccination would be among international guests to a large ...
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Cross-replication association

In a genomic study of patients infected with SARS-CoV-2, scientifics detected cross-replicating associations with rs11385942 at locus 3p21.31 , the association signal spanned the genes SLC6A20, LZTFL1,...
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Why are government decisions being led by the number of COVID CASES (as opposed to actual deaths)? [closed]

Since the early days of COVID-19, when very little information was available regarding this new virus, we now have an abundance of data. Data such as: Cases recorded, per nation, per time period ...
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Is COVID-19 spread by exhaled cigarette smoke?

Here in the Basel, Switzerland area there are mask mandates when shopping or taking public transit. Yet every day when I walk to or from the train station, I see dozens of people smoking outside the ...
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Can the flu mortality be as high as covid-19 in some countries?

According to this Up to 650,000 people die of respiratory diseases linked to seasonal flu each year This marks an increase on the previous global estimate of 250 000 – 500 000, which dates from over ...
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Why does R_t start so high for COVID in these models?

The site rt.live is a website for tracking the Rt value for COVID-19 for states in the U.S. The Rt value is the average number of people infected by someone who is infected with COVID-19. In almost ...
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Can certain medications cause false positives for COVID-19?

I was told by some colleagues at work that certain medications if they were taken by a person can cause antibody COVID-19 tests to test positive, is it possible ? If so how is that possible ?
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How does ELISA test for COVID antibodies detect antibodies specific to SARS-CoV-2?

I know how ELISA can be used to detect particular antigens by using antibodies specific to the antigen. How is it being used to detect SARS-CoV-2 specific antibodies? I realise that one possible ...
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Is inoculation against covid-19 an option?

Covid-19 can cause serious illness or death, and it can take survivors a very long time to recover, and even then it is unsure if recovery will be complete. The policies put in place to curb the ...
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corona virus vaccine side effects [closed]

First I like to mention that I have no medical background I have read that there are 2 types of vaccines for the corona virus currently developed A RNA based vaccine, which is based on a novel ~...

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