Questions tagged [cancer]

The disease caused by an uncontrolled division of abnormal cells in a part of the body or when describing a malignant growth or tumor resulting from the division of abnormal cells.

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Why isn't there a notable "graft versus host" effect in lymphoma?

In other words, why don't we use allogenic hematopoietic stem cell transplantation (in general) for lymphomas? (with the exception of being occasionally used in highly selected lymphoid malignancies ...
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Is it common for FIGO stage 3 ovarian cancer to have involvement of lymph nodes along greater curvature of the stomach?

I'm a medical student and I'm doing research on cancer. My thesis is about lymph nodes and I'm stumped with the question above. I can't find much literature pertaining to the current topic and would ...
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Does EMF radiation, higher than safety limits suggest, cause cancer? [duplicate]

Does EMF(radio and microwave spectrum) radiation cause cancer, and what are the safety limits that WHO or independent scientists suggest? I read this article below; is this true? Most cancer in ...
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Are people who suffer from autoimmune diseases less likely to get cancer? [closed]

Autoimmune diseases are caused by one's own immune system doing too much. In such a case, will it have the positive side effect of more protection against actual disease such as cancer?
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Is there reasonable cause to suspect that taking creatine increases risk of testicular cancer causatively?

A 2015 study finds a significant association between muscle-building supplements (MBS) and testicular germ cell carcinoma (TGCC) with seemingly massive odds ratios. There was a wave of panic about ...
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Is it true that surgery for cancer can cause the cancer to spread? [closed]

This cancer.org article says: You may have heard that surgery for cancer can cause the cancer to spread. It's very rare for surgery to cause cancer to spread. Advances in equipment used during ...
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Is it true that freckles have zero potential for malignant transformation?

This New York City dermatologist called Dr. Bobby Buca on this web page says: "Freckles and moles have two things in common: there is a genetic tendency to get them, and both are darker than the ...
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Probability to develop a new type of melanoma

I saw that there are different types of melanoma: some are more aggressive and others are less dangerous. From what I understood searching on web, the causes of melanoma are not clear but there are ...
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Modern explanation of the Burkitt's lymphoma geography [closed]

In Dr. Arnold Levine "Viruses", a book published in 1991, it's noted that while association between Burkitt's lymphoma and the Epstein-Barr virus is established, the correlation between the ...
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Does black tea increase the risk of breast cancer?

Some studies suggest that black tea consumption may be positively associated with development of breast cancer. Here's link to one study result. Is it a fact or just a hypothesis?
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What are potentially carcinogenic prostatic secretions

In the answer by @Jan to the question What is "stagnation in the prostate"? it is pointed out via Rider, et al. (2016) what is sometimes referred to as the prostate stagnation hypothesis. ...
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Why is sepsis more common with leukemia than with cancers involving physical tumors?

Does it have something to do with differences between leukemia versus other cancers, or differences between the treatments of leukemia versus other cancers? Quote from the source: People with cancers ...
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Sun exposure damage

I had a lot of times in my life when I got seriously sunburned (my skin got extremely red). Though, after the sunburns pass, I become a lot darker and tanned and then I do not get burned any more, ...
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Meaning of "early neurotoxicity" in description of methotrexate treatment effects - at an early age? or an early-stage neurotoxicity?

From a guideline: Due to the inhibitory effect of methotrexate on DHPR and the interaction with dihydrofolate reductase (DHFR), this treatment may lead to HPA and early neurotoxicity, possibly ...
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Why are the surgical margins for invasive ductal carcinoma less than the margins required for invasive ductal carcinoma in situ?

Per the NCCN guidelines version 4.2020 (which is unfortunately pay-walled), for invasive ductal carcinoma (IDC), the recommended margins are no tumor on ink, while isolated ductal carcinoma in situ (...
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How effective is topical fluorouracil to treat facial superficial basal cell carcinoma (BCC) after Imiquimod 5% cream failed to treat it?

Both Imiquimod 5% cream and topical 5-Fluorouracil (5-FU) have been used to treat basal cell carcinoma (BCC) with a fair amount of success (~60 to 90% success rate at 5-year follow-up) {1}. Imiquimod ...
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Should Imiquimod 5% cream be applied 1 cm beyond the target tumor when treating a facial basal cell carcinoma, and if so, why?

I read on https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/20723s016lbl.pdf (mirror): 364 patients with primary superficial basal cell carcinoma (sBCC) were treated with Aldara Cream or ...
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What is the success rate of topical imiquimod 5% cream to treat infiltrative basal cell carcinoma (BCC)?

What is the success rate of topical imiquimod 5% cream (US brand: Aldara) to treat infiltrative basal cell carcinoma (BCC)? So far I've only found some case study {1} and some study on using topical ...
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How is Allred score found in an IHC breast tissue image?

In breast cancer immunohistochemistry (IHC), usually breast tissues are stained with ER/PR (Estrogen/Progesterone) stains so that ER/PR receptors (if present) show up. Allred score is a way of finding ...
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Chronic Myeloid Leukemia blast percentage

I'm trying to understand the oncogenesis of CML. I have a question about CFC cells and blast cells. Are those the same? I know that in the chronic phase of CML there is a blast percentage of 1-10% of ...
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Teeth cancer in Humans [closed]

https://en.wikipedia.org/wiki/Cancer https://en.wikipedia.org/wiki/Human_tooth https://www.google.com/search?q=teeth&oq=teeth&aqs=chrome..69i57j0l3j69i60.10521j0j7&client=ms-android-lava&...
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What does the drug manufacturer mean by "stopping blood vessels growing in the cancer"?

From the leaflet of a drug called Revlimid(R) (active ingredient: lenalidomide): How Revlimid works Revlimid works by affecting the body’s immune system and directly attacking the cancer. It works in ...
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Studies On The Affect Of Immunotherapy On Larynx Surgeries

I've been searching online for a study regarding the affect of immunotherapy on the necessity for an affected individual diagnosed with laryngeal cancer to require larynx surgery, to no avail. Could ...
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How long do trials for "cancer vaccines" usually take?

2 years ago we've heard about a "cancer vaccine" be ready to be tested in humans. Cancer vaccine trial . By that time a person I know (with no experience whatsoever in Medicine) told me he &...
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Do these diagrams have an official name (treatment plan, treatment schedule, protocol)

I am doing research on treatment plans and protocols in order to design software to minimize error when indicating medicine, procedures, exams, etc. We also want to monitor treatment and somehow ...
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Can cancer incidence rates, calculated from the general population, be used in primary care?

I calculated incidence rates (IR) for colorectal cancer using an age-period-cohort model. Is it useful for GPs to use such age, gender and anatomical sub-site specific IRs as a baseline risk, during ...
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Meaning of "I" in a table in a study poster

From a poster to a study: I don't understand the meaning of "I" used in several fields of this table. What could it mean? I've read the abstract of the study but still cannot get it. The ...
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Meaning of "(ref)" in a table describing the characteristics of patients taking part in a cancer study

From a poster describing a study in cancer patients. This is from a table in the poster, which describes the characteristics of the patients (Age groups, Sex ect.) You can see what percentage of the ...
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Meaning of "the benchmark for median survival"

From the Background section of a clinical trial poster: Good performance, unresectable stage III non-small cell lung cancer (NSCLC) patients should receive standard-of-care treatment, i.e. Concurrent ...
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Why is the Virchow node involved in Gastric Adeonocarcinoma?

The lymph node drainage of the stomach is via the pyloric and related lymph nodes. Either way, the supraclavicular node (Virchow's node) is not the first lymph node that drains the Stomach. According ...
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Is biopsy still required for cancer diagnosis given that advanced medical imaging is now available?

For cancer diagnosis, there is biopsy, an invasive technique. However, PET CT, SPECT CT, MRI are non-invasive. Do oncologists still require the use of biopsy to ascertain type of cancer, i.e., to ...
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Why does metastatic bone cancer present as back pain that is "worse at night"?

One "classic" presentation of metastatic bone cancer is back pain that "tends to be worse at night and may get better with movement" - American Cancer Society. Googling "back pain worse at night from ...
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Diameters of vessels metastases spread through

As I know, one of the way tumor may metastasis is, forced by hypoxia, creating new vessels near it, connecting them to the main circulatory system and then spread cells through the blood. If ...
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Do carrots cure cancer?

**Do carrots cure cancer? ** There’s a lot of unsubstantiated information online about carrots and cancer. There are even a few books. What does science actually say about how carrots affect cancer ...
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Why aren't purine analogs effective in non-hematological malignancies?

FDA has approved many purine analogs e.g. thioguanine, cladribine, pentostatin, mercaptopurine for various forms of leukemia and/or lymphoma, but none for non-hematological malignancies. What makes ...
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How many people are affected by hepatocellular carcinoma (HCC) worldwide today?

Does anybody know how I can learn how many people are affected by hepatocellular carcinoma (HCC) worldwide today? I need this information for a research study; I tried to search on Google but I only ...
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Why haven’t other research groups invested into antineoplastons when it comes to cancer treatment?

I recently stumbled upon antineoplastons which is a family of drugs based on chemical natural products prevalent in human blood and urine. I have only been able to find one person administering ...
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What is the relationship between cancer and sugar? [closed]

I was watching "The Magic Pill" documentary series on Netflix. And, a woman indicated that she completely cured a fairly aggressive breast cancer by eliminating just about all sugars and most ...
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Do Tamoxifen and other similar SERMs reduce chest fat chronically or permanently?

I am sorry if it mistaken (please comment or suggest an edit to fix) but by chronically I mean as long as the molecule is administered and effective and by permanently I mean after the molecule was ...
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How exactly does induced Scalp Hypothermia prevent alopecia (hair loss) during chemo therapy?

Recent studies 1 of women getting chemo for early-stage breast cancer have found that at least half of the women using one of these newer devices lost less than half of their hair. 2 Scalp ...
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Is tacrolimus carcinogenic and if so, what causes it to be?

The FDA issued a health warning 1 regarding the possible cancer risks of tacrolimus ointment, however, British dermatologists2 don't consider this a significant concern and they are increasingly ...
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What kind of cell kill probabilities per division you get with chemotherapy?

As I understand it, many chemotherapeutic drugs target cell division, with the theory that a constant kill probability per cell division kills fast-replicating cancer cells faster than slow-...
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3 votes
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Is there a cancer treatment method that uses a poison and an antidote?

I am wondering if the following method (or similar variations) for treating cancer exists and if so if it works. The metod is to deliver an ”antidote” to all cells (or all cells of a specific type) ...
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What is the current standpoint on cooking with olive oil?

Usually I make dishes by adding a tablespoon of olive oil to the meat or vegetables and just have them for some time on a teflon pan. I know that frying is done on high temperatures and results in ...
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Cancer treatment through regulation of myeloid-derived suppressor cells

There are many ongoing clinical trials that leverage the power of the immune system to recognize tumor cells such as CD47 and PDL1/PD1, and even engineered T cells! I ran across an immune cell type ...
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If screening for a disease is not recommended, should someone with positive findings take further action?

Consider the following hypothetical case: Mary is a woman who has no ovarian cancer symptoms and is not known to have a high-risk cancer syndrome. She nevertheless gets a transvaginal ultrasound and ...
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Why is there is no screening for Ovarian Cancer?

From what I have read it is not considered effective to screen for ovarian cancer in non-symptomatic women. Would it not be worth doing an ultra-sound scan, then if there are growths found, do a ROMA ...
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Does intermittent fasting induce autophagic cell death?

https://www.cancertherapyadvisor.com/home/tools/fact-sheets/intermittent-fasting-and-cancer/ In vitro and in vivo animal studies suggest that PF inactivates pro-proliferative pathways, while ...
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How safe is low frequency radiation in I.T. edge cases? (5G, etc)

Closely Related: 5G Radiation Dangerous? Being inundated with all kinds of 5G health statements, (for & against), I noticed a weird trend - the absence of cumulative radiation studies. Question: ...
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Barrett's esophagus (BO) and proton-pump inhibitors (PPIs)

I have come across an interview with a European gastroenterologist (apparently from 2006) where he argues that in cases where a reflux disease does not cause typical symptoms even the presence of a ...
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