Questions tagged [autoimmune-disease]

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Is the HSP70i protein involved in the cellular damage caused by most autoimmune disorders?

Inducible heat shock protein 70 (HSP70i) has gained attention for its potential role in treating vitiligo, an autoimmune skin disease. HSP70i mediates the depigmentation process caused by rogue T-...
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what is the mechanism through which TLR 7 agonist causes autoimmune disease?

TLR 7 agonist has been linked with development of autoimmune disease, namely lupus like disease. The question is, why does it happen? I think a mechanism of why it happens would also reveal answers to ...
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What are the pathologies most likely to occur after leukemia? [closed]

I heard leukemia survivors are at risks of multiple subsequent conditions. What are they? In particular, is there a correlation between leukemia and subsequent auto-immune diseases? I remember having ...
Samuel Nihoul's user avatar
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Can autoantibodies found in the father affect the embryo, and how?

From "Folate Receptor Alpha Autoantibodies in Autism Spectrum Disorders: Diagnosis, Treatment and Prevention" (2021): Comparison of the Childhood Autism Rating Scale (CARS) after 2 years of ...
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What are the risks associated with imidazoquinoline adjuvant (used in one Covid-19 vaccine) related to development of autoimmune diseases?

Covaxin is an inactivated virus-based COVID-19 vaccine developed by Bharat Biotech. Recently, the Brazilian health regulator Anvisa raised few concerns regarding Covaxin, one of which was- use of a ...
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Does Coriander Seed increase or decrease tnf alpha and il-6?

I came across two different papers claiming the opposite thing. Although there was a dose dependent increase in serum TNF-α levels in the CSHE treated groups as compared to control, the synovial ...
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If we could remove all auto-antibodies would the auto-immune disease get cured?

Some people tell me that yes, by eliminating all auto-antibodies the auto-immune disorder would cease (and maybe some old-cell/toxins removal abilities as well). Others say that auto-antibodies are ...
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Why is multiple sclerosis associated with trigeminal neuralgia?

Multiple sclerosis (MS) is classically described as: an immune-mediated inflammatory disease that attacks myelinated axons in the central nervous system (Luzzio, n.d.). Since MS only involves the ...
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How can we stop our immune system from producing a particular antibody? [closed]

I have always been fascinated with our immune system and, although it is not my specialization, I have been reading about it lately. Auto immune diseases are particularly interesting because it seems ...
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Can IVIG treatment increase risk of infections?

Intravenous Immunoglobulins (IVIG) are often used to treat patients with impaired antibody production or autoimmune conditions[1]. However, according to this paper[2], it can also inhibit antibody ...
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Is it possible to have an autoimmune disease and no C-reactive protein in blood serum?

Autoimmune diseases cause inflammation. C-reactive protein (CRP) should be elevated in a person with inflammation. Is it possible that a person with an autoimmune disease (e.g. autoimmune hemolytic ...
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Can SARS-CoV-2 be a potential cause for Guillain-Barré syndrome?

According to Wikipedia :- ...Although the cause is unknown, the underlying mechanism involves an autoimmune disorder in which the body's immune system mistakenly attacks the peripheral nerves and ...
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Is a patient who has an autoimmune disease immunocompromised?

If a patient has an autoimmune disease - Hashimoto's Thyroiditis, for example - and is not on immunosuppressants, are they at a higher, lower or equal risk of ending up with COVID-19 (or any other ...
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Can we slow the advancement of Rheumatoid Arthritis (RA) with immunosuppressants?

Rheumatoid arthritis (RA) is a long-term autoimmune disorder that primarily affects joints (Wikipedia, n.d.). If the general cause is over activity of inflammatory cytokines (Nalbant & Birlik, ...
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Why does hydrops fetalis occur in erythroblastosis fetalis?

I understand the pathophysiology of hydrops fetalis and erythroblastosis fetalis independently, but not why the edema occurs during erythroblastosis fetalis. For example, Langman's Embryology has ...
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What is the difference between eczema and urticaria?

What is the difference between eczema and urticaria? I want to know the pathophysiology and most common causes to understand why they are different !
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Are type 2 hypersensitivities autoimmune diseases?

I'm learning about hypersensitivities and it seems to me that all type 2 hypersensitivities are autoimmune diseases; also all examples of type 2 hypersensitivity I've heard so far are also classified ...
Lukeception's user avatar
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Is autism an autoimmune disease?

I have not a license on Science Direct and I can't read more than the abstract of this article: Is autism an autoimmune disease? I would like to know from experts (and read the articles you quote if ...
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Might calcium supplements be behind Granulomatosis With Polyangiitis (Wegener's)?

Disclaimer: I have no formal medical or scientific education. Abstract My thesis is that the calcium created by man-made processes is not the correct isotope to support the biological functions for ...
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What advanced detection schemes can provide low cost screening for Latent Autoimmune Diabetes?

Latent Autoimmune Diabetes in Adults (LADA) may be more prevalent than previously believed. A common marker for the most common form is glutamic acid decarboxylase 65 (GAD-65). Are there low cost and ...
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"AGE" meaning in the term AGE-associated autoantibodies?

What is the "AGE" in AGE-associated autoantibodies? Please describe it if you can. It was mentioned in the book "The End of Alzheimer's: The First Programme to Prevent and Reverse the Cognitive ...
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How does interferon beta 1-A help patients with multiple sclerosis?

I know that azathioprine weakens the immune system by reducing white blood cell count. I've read that interferons boost the immune system against viruses. They seem to have different functions, but ...
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3 votes
2 answers
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Vaccines and autoimmunity concerns

Medical papers/books exist linking vaccines to autoimmunity yet I am not able to decide whether they should be considered sound and peer reviewed scientific studies or not. Some examples are: "rare ...
Marco Disce's user avatar
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1 answer
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APC cells - autoreactivity [closed]

How can APC cells become autoreactiv against own antigens if they only have PRR as recognition complexes - and are not under central/peripheral immune tolerance?
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1 answer
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How does immunosuppressant affect immune system?

I'm talking Immuran (azathioprine) and I would like to know what it does to immune system exactly. I'm not a doctor but I'm asking here just to learn. Does it kill all white cells? Does it reduce the ...
user2824371's user avatar
1 vote
1 answer
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Rheumatoid arthritis and hormones

If rheumatoid arthritis symptoms improve during pregnancy, why women are not treated with hormones?
rkj's user avatar
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Knowing the root cause of one's hypothyroidism? How to know if it's Hashimotos Disease?

Ever since I was a teenager, I've been treated for hypothyrodism (underactive thyrodid). However, I don't recall the official diagnosis process and am not sure if it was ever conducted. My grandmother,...
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Are there any long-term health benefits/ disadvantages of wearing socks, especially woolies?

Are there any long-term health benefits/ disadvantages of wearing socks, especially woolies ?
user7094's user avatar
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1 answer
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Why do some General Practioners not consider Fibromyalgia as a genuine, real auto-immune disorder?

Before I was diagnosed with my Fibromyalgia by my rheumatologist, I had told my Canadian General Practitioner that my USA Family Doctor had thought I had thought I had Fibromylagia, and my G.P. ...
Butterfly and Bones's user avatar
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Swab tests reveals I have a staph infection. Can it tell if it's MRSA? Or is that a different test? If so, can that distinguish HA-MRSA & C-MRSA?

I had a blistered rash that kept spreading so my doctor took a swab to see if there was any kind of bacterial cultures present. The results came back today -- I am positive for a staph infection. ...
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1 answer
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How is sunlight a Lupus trigger for some? What exactly about the sun often causes Lupus flare-ups?

There are different triggers for those diagnosed with Lupus, and a common trigger is sunlight. What is it about the sunlight the causes the body to start attacking itself? Does the body not know how ...
Butterfly and Bones's user avatar
4 votes
1 answer
285 views

Top medications to treat symptoms of Lupus?

Being new to the Lupus world, I am hearing conflicting views from all sorts of physicians (living both in Canada and the USA). What are the top medications to treat the symptoms of Lupus? I heard ...
Butterfly and Bones's user avatar
3 votes
1 answer
6k views

Do collagen supplements help ease some of the symtoms of Lupus?

As someone recently diagnosed with borderline Lupus (I have all the symptoms except the butterfly rash), my doc recommended collagen supplements. Does it truly help ease the symptoms joint paint in ...
Butterfly and Bones's user avatar
7 votes
1 answer
237 views

Multiple Sclerosis and Chemotherapy

I caught part of a cable television program but I ended up falling asleep but it seemed interesting (I was just exhausted). Basically it talked about chemotherapy being a so-far proven treatment for ...
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7 votes
1 answer
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Can blood transfusion help in case of scleroderma?

Can blood transfer can somehow help a case of scleroderma? I know it's not the way to cure it, but I was just wondering if this can slow down the body destruction made by the faulty lymphocytes. ...
guest's user avatar
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9 votes
1 answer
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Hashimoto thyroiditis leading to severe psychological problems and behavior changes?

Can Hashimoto thyroiditis lead to psychological problems and severe behavioral changes? Do existing psychological problems (anxiety, depression, etc.) 'compound' when layered with Hashimoto ...
Re'eh's user avatar
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6 votes
1 answer
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How do steroids work in treating a multiple sclerosis relapse?

I have been trying to find this out with no luck. I understand that they don't affect the long term progression of the disease so don't seem to affect the demyelination, but I'm not sure how they ...
Meep's user avatar
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15 votes
1 answer
9k views

Risks of blood donation with autoimmune diseases

People with autoimmune diseases are generally either forbidden or discouraged from donating blood. Example: People who have autoimmune diseases (such as autoimmune thyroid disease, ankylosing ...
YviDe's user avatar
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3 votes
1 answer
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Causes of polypoid foveolar hyperplasia

Six years ago during an endoscopy, the gastroenterologist noted that he had seen a small nodule forming in my stomach. A recent endoscopy revealed 3 nodules. The biopsies showed that they were benign,...
smeeb's user avatar
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5 votes
1 answer
226 views

Rheumatoid arthritis heritability

Is there any scientific information available on how likely it is that a child with one parent with rheumatoid arthritis will have the same condition? I know there's probably not going to be any hard ...
YviDe's user avatar
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9 votes
1 answer
366 views

Comorbidity of autoimmune diseases

Do people who have one autoimmune disease (for example rheumatoid arthritis, Crohn's, Hashimoto hypothyroidism) have a statistically significant higher chance of developing another autoimmune disease ...
YviDe's user avatar
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2 votes
0 answers
979 views

Crohn's disease and sauna

If you have Inflammatory bowel disease (IBD) (for example Crohn's or Ulcerative Colitis) is sauna good for you or bad? And how often you can go to sauna? Every day? I think it can be good because ...
Alexan's user avatar
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4 votes
1 answer
6k views

What is normal range of Anti TPO antiodies test?

What is normal range of Anti TPO antiodies test? My relative have undergone this test and got value 207. Her TSH is also 5.8
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