Questions tagged [antibodies]

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How does ELISA test for COVID antibodies detect antibodies specific to SARS-CoV-2?

I know how ELISA can be used to detect particular antigens by using antibodies specific to the antigen. How is it being used to detect SARS-CoV-2 specific antibodies? I realise that one possible ...
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Can this method of immunization for horses serve as a COVID-19 vaccine for humans?

A group of scientist developed Equine polyclonal antibodies (EpAbs) obtained after immunization of horses with the receptor-binding domain of the SARS-CoV-2 viral Spike glycoprotein. https://ri....
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The placebo effect [closed]

Is it possible to eliminate the groups of placebos in all those clinical trials that have a precision medicine nature? Since if it is precision medicine, it is supposed to cure 100% of those affected ...
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What's the probability of catching COVID-19 more than once?

In this YouTube video Can you catch coronavirus more than once? l GMA Digital the doctor says that "we don't really know yet". Assuming that the answer could be yes, what's the probability ...
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The relationship between the rate of decrease of antibody production and long term immunity

I am seeing a large number of COVID-19 articles which point to low levels of antibody production 2-3 months after infection. They all point to this being an indicator that infection may not provide ...
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False Positive PCR - COVID-19 and possible reinfection when antibodies value is +7.0

A friend of mine was detected COVID-19 positive through PCR one month back. He was asymptotic as per doctors and had no symptoms. He quarantined himself and increased his intake of water. After 1 ...
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Is there any information on the lifespan of SARS-CoV-2 antibodies?

Like all cells, antibodies die off after a period of time. A human body may (or not) be able to efficiently replace or replicate these antibodies. Whether the original antibodies were generated ...
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Can the specificity of a COVID-19 antibody test be improved by testing twice?

My question is fairly simple: There is a COVID-19 antibody test with a worst-case specificity of 98%, meaning that it yields potentially up to 2% false positives. While that number is not bad it is ...
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142 views

Why are antibodies not used as treatments for infectious diseases?

It seems like human monoclonal antibodies would be the ideal treatment for any serious infectious disease. Unlike vaccines, they don't depend on having the immune system recognize the right epitope, ...
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Are there any other reasons than mutation that could cause a virus to be able to infect the same person twice?

If you are infected by a virus, and subsequently survive it and get completely rid of the infection, are there any other possible reasons for the same virus to be able to infect you again any time in ...
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932 views

Does the blood removed from the body still have immunity?

I know that blood contains white blood cells (which attack pathogens). Suppose we take half a liter of blood out of the body and implant the virus into it. Can the white blood cells in that half a ...
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Why can't simple blood transfusions be used for treatment of COVID-19, instead of plasma transfusions? [closed]

It has been recently been shown that convalescent plasma from previously infected patients can be used to help others gain immunity against the disease. But why do we need to use plasma for this ...
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What does it mean when someone has Coronavirus antibodies?

I'm a bit confused reading articles like this: https://www.nytimes.com/2020/04/23/nyregion/coronavirus-antibodies-test-ny.html One of every five New York City residents tested positive for antibodies ...
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Ratio of PCR to antibodies positive Covid-19 tests in studies outside USA?

CNN reported: Two studies involving antibody blood tests in California -- one in Los Angeles County and the other in Santa Clara County -- so far have suggested that the number of people already ...
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A cheap and easy inactivated vaccine for COVID-19

Suppose a person with COVID-19 coughs into a bag. Let the bag sit in the sun for, say, 72 hours -- so as to make the virus inactive. Could a healthy person breathe in the inactivated virus from the ...
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Do coronavirus antibodies give you any immunity?

According to Coronavirus antibodies may not make you immune, WHO warns There is no evidence to suggest that recovered coronavirus patients and former asymptomatic carriers who have coronavirus ...
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If COVID-19 binds to GRP78 could a GRP78 dose inactivate the virus?

This research found that the COVID-19 spike protein binds to the cell surface receptor GRP78. If we could inject a large amount of GRP78 into patients could it saturate the virus particles, and ...
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Are false positives from Cellex’s Coronavirus antibody test systemic?

The FDA just approved the first antibody test for the Coronavirus, made by Cellex. The test has a significant false positive rate though (see here). Now for a lot of tests, false positives can be ...
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Allowing persons having sars-cov-2 antibodies to move freely

Would it make sense from the public safety point of view to allow the persons already having the antibodies to move more freely than the persons not having the antibodies? Or it is more of an ethical ...
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Is there a way to test for covid 19 after recovery?

I had symptoms that could have been corona symptoms last week. Unfortunately the testing capacity in my country (Germany) is not sufficient to test every person with symptoms at the moment, so only ...
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Is there a limit to the number of different antibodies one individual can have in their body? [duplicate]

If my understanding is correct, we create antibodies after vaccines and after getting infections. So, after 10 vaccines and 2 contracted diseases, I can have in my body antibodies for 12 types of ...
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“AGE” meaning in the term AGE-associated autoantibodies?

What is the "AGE" in AGE-associated autoantibodies? Please describe it if you can. It was mentioned in the book "The End of Alzheimer's: The First Programme to Prevent and Reverse the Cognitive ...
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What are some better alternatives to HIV antibody test?

I've been having HIV symptoms for more than 4-5 months, I reran the antibody test for five times it all became negative, the doctor said that you didn't have to worry about HIV anymore as all the ...
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Is the second vaccine dose necessary if seroconversion occurred after the first dose?

My question is applicable to all multi-dose vaccines with vaccination intervals of several weeks, though the specific case that triggered my question was the chickenpox vaccine Varilrix/GSK. My ...
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Does the saliva of a person just recovered from an infectious disease help to cure another persons having the same disease?

I have always had this 'weird' thought (But could never quite test it...). Would the saliva contain antibodies, or other immuno-boosting substances that can help fight off the same pathogen in another ...