Questions tagged [antibodies]

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After vaccination did SARS-Cov-2 Spike (S) protein antibodies test - is my number big or small? [closed]

After vaccination with Chinese vaccines I did SARS-Cov-2 Spike (S) protein antibodies test. I was told if I had result more than 0.8 it means vaccine "worked". But I got result: 3.4. I am ...
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Why was the fact that the Fc-part of an antibody is crystallizable important enough that the part was named after it? (Fc =“Fragment crystallizable”)

The typical Y-shape structure of an antibody is often further divided into three parts which correspond to the fragments one obtain when the antibody is digested by the protease papain. Those are: ...
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Meaning of covid-19 cases reports on news, how to resolve contradiction with mass IgG tests results?

there are covid-19 new cases report on tv and newspapers, like here (russia 24 tv channel, in russian) and here (a news agency website, also in russian). as i know, these are based on PCR tests. as i ...
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Do covid vaccines increase the risk of antibody-dependent enhancement?

A QAnon video which takes Nobel Prize winner Luc Montagnier's suspect claims about covid vaccination and multiplies them beyond recognition states that mass vaccination will lead to mass ADE, and that ...
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1answer
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Antibody test after vaccination with BBIBP-CorV

After vaccination with BBIBP-CorV (inactivated) which of the following tests can be taken to determine if the vaccine produced an immune response: IgM for N protein IgG for N protein IgG for S ...
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What protection does T-cell immunity confer for Covid?

This preprint, which was just released today, says that while some of the Covid-19 variants evade antibody immunity, they do not evade T-cell immunity. It says that this is true both of T-cell ...
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Effects of anti-Rh(D) antibodies on the fetus

Rh disease is caused by the irruption in the fetal circulation of anti-Rh(D) antibodies. This only happens when there has been a prior exposure of the mother to Rh+ RBC. To prevent Rh sensitization ...
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If we could remove all auto-antibodies would the auto-immune disease get cured?

Some people tell me that yes, by eliminating all auto-antibodies the auto-immune disorder would cease (and maybe some old-cell/toxins removal abilities as well). Others say that auto-antibodies are ...
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How can we stop our immune system from producing a particular antibody? [closed]

I have always been fascinated with our immune system and, although it is not my specialization, I have been reading about it lately. Auto immune diseases are particularly interesting because it seems ...
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How does ELISA test for COVID antibodies detect antibodies specific to SARS-CoV-2?

I know how ELISA can be used to detect particular antigens by using antibodies specific to the antigen. How is it being used to detect SARS-CoV-2 specific antibodies? I realise that one possible ...
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Can this method of immunization for horses serve as a COVID-19 vaccine for humans?

A group of scientist developed Equine polyclonal antibodies (EpAbs) obtained after immunization of horses with the receptor-binding domain of the SARS-CoV-2 viral Spike glycoprotein. https://ri....
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The placebo effect [closed]

Is it possible to eliminate the groups of placebos in all those clinical trials that have a precision medicine nature? Since if it is precision medicine, it is supposed to cure 100% of those affected ...
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The relationship between the rate of decrease of antibody production and long term immunity

I am seeing a large number of COVID-19 articles which point to low levels of antibody production 2-3 months after infection. They all point to this being an indicator that infection may not provide ...
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1answer
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False Positive PCR - COVID-19 and possible reinfection when antibodies value is +7.0

A friend of mine was detected COVID-19 positive through PCR one month back. He was asymptotic as per doctors and had no symptoms. He quarantined himself and increased his intake of water. After 1 ...
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Is there any information on the lifespan of SARS-CoV-2 antibodies?

Like all cells, antibodies die off after a period of time. A human body may (or not) be able to efficiently replace or replicate these antibodies. Whether the original antibodies were generated ...
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Can the specificity of a COVID-19 antibody test be improved by testing twice?

My question is fairly simple: There is a COVID-19 antibody test with a worst-case specificity of 98%, meaning that it yields potentially up to 2% false positives. While that number is not bad it is ...
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159 views

Why are antibodies not used as treatments for infectious diseases?

It seems like human monoclonal antibodies would be the ideal treatment for any serious infectious disease. Unlike vaccines, they don't depend on having the immune system recognize the right epitope, ...
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Are there any other reasons than mutation that could cause a virus to be able to infect the same person twice?

If you are infected by a virus, and subsequently survive it and get completely rid of the infection, are there any other possible reasons for the same virus to be able to infect you again any time in ...
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935 views

Does the blood removed from the body still have immunity?

I know that blood contains white blood cells (which attack pathogens). Suppose we take half a liter of blood out of the body and implant the virus into it. Can the white blood cells in that half a ...
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Why can't simple blood transfusions be used for treatment of COVID-19, instead of plasma transfusions? [closed]

It has been recently been shown that convalescent plasma from previously infected patients can be used to help others gain immunity against the disease. But why do we need to use plasma for this ...
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1answer
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What does it mean when someone has Coronavirus antibodies?

I'm a bit confused reading articles like this: https://www.nytimes.com/2020/04/23/nyregion/coronavirus-antibodies-test-ny.html One of every five New York City residents tested positive for antibodies ...
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Ratio of PCR to antibodies positive Covid-19 tests in studies outside USA?

CNN reported: Two studies involving antibody blood tests in California -- one in Los Angeles County and the other in Santa Clara County -- so far have suggested that the number of people already ...
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A cheap and easy inactivated vaccine for COVID-19

Suppose a person with COVID-19 coughs into a bag. Let the bag sit in the sun for, say, 72 hours -- so as to make the virus inactive. Could a healthy person breathe in the inactivated virus from the ...
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439 views

Do coronavirus antibodies give you any immunity?

According to Coronavirus antibodies may not make you immune, WHO warns There is no evidence to suggest that recovered coronavirus patients and former asymptomatic carriers who have coronavirus ...
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1answer
67 views

If COVID-19 binds to GRP78 could a GRP78 dose inactivate the virus?

This research found that the COVID-19 spike protein binds to the cell surface receptor GRP78. If we could inject a large amount of GRP78 into patients could it saturate the virus particles, and ...
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Are false positives from Cellex’s Coronavirus antibody test systemic?

The FDA just approved the first antibody test for the Coronavirus, made by Cellex. The test has a significant false positive rate though (see here). Now for a lot of tests, false positives can be ...
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67 views

Allowing persons having sars-cov-2 antibodies to move freely

Would it make sense from the public safety point of view to allow the persons already having the antibodies to move more freely than the persons not having the antibodies? Or it is more of an ethical ...
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1answer
258 views

Is there a way to test for covid 19 after recovery?

I had symptoms that could have been corona symptoms last week. Unfortunately the testing capacity in my country (Germany) is not sufficient to test every person with symptoms at the moment, so only ...
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Is there a limit to the number of different antibodies one individual can have in their body? [duplicate]

If my understanding is correct, we create antibodies after vaccines and after getting infections. So, after 10 vaccines and 2 contracted diseases, I can have in my body antibodies for 12 types of ...
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121 views

“AGE” meaning in the term AGE-associated autoantibodies?

What is the "AGE" in AGE-associated autoantibodies? Please describe it if you can. It was mentioned in the book "The End of Alzheimer's: The First Programme to Prevent and Reverse the Cognitive ...
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What are some better alternatives to HIV antibody test?

I've been having HIV symptoms for more than 4-5 months, I reran the antibody test for five times it all became negative, the doctor said that you didn't have to worry about HIV anymore as all the ...
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1answer
134 views

Is the second vaccine dose necessary if seroconversion occurred after the first dose?

My question is applicable to all multi-dose vaccines with vaccination intervals of several weeks, though the specific case that triggered my question was the chickenpox vaccine Varilrix/GSK. My ...
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Does the saliva of a person just recovered from an infectious disease help to cure another persons having the same disease?

I have always had this 'weird' thought (But could never quite test it...). Would the saliva contain antibodies, or other immuno-boosting substances that can help fight off the same pathogen in another ...