Questions tagged [medications]
Questions related to intake, use, safety, side effects, pharmacokinetics, or any other aspect of a drug prescribed by a physician.
324
questions
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9 views
How exactly can a drug affecting squalene epoxidase affect the methylation cycle, necessitating the use of 5-MTHF? [migrated]
I found a case report in which the authors say that Terbinafine might have possibly affected the methylation cycle in a patient, necessitating the prescription of 5-methylfolate to correct the ...
-2
votes
1answer
29 views
Side-effects or other medical conditions for diabetic patients
I have a database of diabetic patients and their medication/lab test data as well.
1) I am planning to run a simple analysis like finding out incidence rate
example: amongst the T2DM patients that I ...
1
vote
2answers
42 views
T2DM medication treatment pathway
I am looking at the T2DM medications specified here and have a few questions about them.
1) Why don't I see drugs like Troglitazone, Tolazamide, Acarbose, Acetohexamide, Chlorpropramide, Miglitol? ...
1
vote
1answer
22 views
Rationale for Pilocarpine instillation after retrobulbar haemorrhage
BACKGROUND: Retrobulbar haemorrhage may occur due to retrobulbar block. Immediate pressure bandage after instilling one drop of 2% pilocarpine and postpone of operation for a week is advised.
What is ...
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0answers
25 views
T2DM diagnosis vs disorder due to T2DM diagnosis?
I have a database of diabetic patients. Mostly 80 % are T2DM patients. Now I would like to identify the T2DM patients based on their conditions reported. I mean when patients visit hospital (diabetic ...
1
vote
1answer
32 views
How to interpret diabetic complications?
I have a database of diabetic patients. Mostly 80 % are T2DM patients. Now I would like to identify the T2DM patients based on their conditions reported. I mean when patients visit hospital (diabetic ...
0
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0answers
32 views
Is there a greater benefit as as to why an ob-gyn will prescribe a birth control with higher risk of Venous Thromboembolism?
It is already known that combined oral contraceptive (COCs) pills increase the risk of serious complications such as Venous Thromboembolism. However there are other options that have relatively much ...
3
votes
1answer
68 views
General purpose vomit response control?
Is there a general purpose antiemetic for vomit response control?
Many vomit control solutions are focused on specific causes for the vomiting. Some common causes of nausea/vomiting:
Cancer ...
0
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0answers
50 views
What is the process of calculating if a molecule is helpful and/or harmful to an organism?
From reading about pharmacology through the years I synthesized from my own prior research that What is the process of calculating if a molecule is helpful and/or harmful to an organism is this:
A ...
2
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1answer
34 views
How does Diabetic specialist clinic work?
I am from IT domain and would like to seek some help on certain medicine related questions
I would like to know how does Diabetic specialist hospital/clinic work for Diabetic patients when compared ...
3
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1answer
40 views
What is daily sedation interruption for ventilated patients?
I was reading about ventilator bundle here and came across this term called Daily Sedation Interruption.
Does this term mean break in giving the sedation drugs?
How can this help in reducing the ...
2
votes
1answer
57 views
T2DM Fasting glucose level - extreme cases
I am working on clinical data analysis and currently dealing with T2DM patients.
When I look at their Fasting glucose level readings, I see that their values range from 0.9 mmol\L to 64 mmol\L
The ...
2
votes
1answer
32 views
Does patients with VAE stay in ICU for longer time?
I was reading online that people when put in ICU under mechanical ventilation, can develop Ventilated associated events.
What I would like to know is does the stay in ICU increases for people who ...
1
vote
1answer
63 views
Fluid balance range for human
I am working on clinical data analysis with patients from icu who are mechanically ventilated and in ICU for 4 or more days.
Currently I tried to calculate their fluid balance based on the input and ...
0
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0answers
45 views
What are the main problems with non-injectable ways to administer molecules into the human body?
From past reading in various sources there seems to me to be many ways to administer molecules into the human body without injections that cause tissue trauma but that these ways generally aren't ...
0
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1answer
28 views
Drug dosage in pharmacology [closed]
Please give a overview about how the dosage of a particular drug (e.g. ciprofloxacin) is determined in pharmacology?
3
votes
1answer
55 views
Why did it take so long to notice that Zantac had carcinogenic ingredients?
Why did it take so long to notice that Zantac had carcinogenic ingredients?
Sanofi is recalling the popular heartburn drug Zantac.
The generic name for the drug is Ranitidine.
Apparently, the ...
1
vote
1answer
105 views
Why many usually-very-painful medical processes aren't done under conscious, generally painless-painkilling?
Many usually-very-painful medical or medical-defined processes such as:
Hair transplant
Lip botox
Fecal impaction removal
Dental cleaning (stone removal)
Aren't being done under conscious, generally ...
3
votes
0answers
29 views
Why/how are some drugs nephrotoxic?
I want to know the (more or less) exact mechanism by which specific nephrotoxic medications damage the kidneys. For some drugs it seems relatively intuitive that they interfere with the function of ...
3
votes
1answer
751 views
Is there an interaction with methamphetamine and dental anesthetic?
According to the sign shown in this post on Reddit, using methamphetamine and dental anesthetic together is lethal.
If you use Methamphetamines (Crystal Meth, Crank, Speed, Glass, Tweak, Yaba)...
0
votes
0answers
10 views
Ergotamine v Sumatriptan for migraine without aura
A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Caferg... - PubMed - NCBI
It is concluded that oral ...
2
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0answers
31 views
Why was Ergotamine (trade name: Cafergot) discontinued in Canada and UK?
My mom in HK was prescribed Ergotamine, but I'm unnerved discontinuation in Canada and UK! Something wrong with it?
Asked
13 Oct 2012 by lucyglitters
i live in the uk and i've been taking it for ...
1
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1answer
33 views
what is the advantages (for patients) in delayed and extended release drugs?
What are the advantages for patients between extended and delayed release drugs?
i understand the difference between these two drugs, but i want to know the advantages to the patients itself between ...
1
vote
0answers
24 views
Lucidity and pain reduction link [closed]
I am a layman, so this is no doubt an overly broad and probably dumb question, but if someone will humor me and attempt to answer, I would greatly appreciate it. Why is it that studies tend to show a ...
2
votes
1answer
38 views
Is Racemic Epinephrine Compatible as Treatment For Anaphylaxis?
I am writing a work of fiction and want it as scientifically accurate as possible.
In theory, is racepinephrine (the active ingredient in Asthmanefrin) compatible as an emergency replacement for ...
4
votes
1answer
48 views
Citrate vs EDTA
What is the difference between the use of «citrate» and «EDTA» as an anticoagulant in medicine (I know that each one is used for some dosages but not the other, but I need to know why)?
2
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0answers
41 views
What is the expected life span of vascular stents?
What is the expected life span of vascular stents?
For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel.
How many pulsating contractions ...
2
votes
0answers
60 views
Can blood flow destroy part of the metal stent in 10 to 40 years?
If a part of the metal stent has not grown into a vessel, can this part of the stent be washed out by the blood flow in 10 to 40 years (theoretically)?
Also are such cases known that blood flow ...
2
votes
3answers
226 views
Why is it that psychoactive drugs tend to be dangerous?
I'm personally not a big fan of recreational drugs, illicit or otherwise, but there's an interesting medical question buried in their use.
Why is it that substances that make you feel good tend to be ...
5
votes
1answer
54 views
How are the administration times for medications determined?
Many prescribed medications give a rate at which to apply the medication, and "over-the-counter" medications often have a minimum time period between dosages the users of the medications are not to go ...
7
votes
1answer
106 views
Why isn't paracetamol routinely combined with n-acetylcysteine?
Whether it's acute large dose paracetamol or long term regular dosage of paracetamol usage, it is a problem for the liver, ototoxic and even potentially life-threatening.
While one might question the ...
4
votes
1answer
59 views
Is it dangerous to administer valproic acid to an adult with an autism spectrum disorder?
I read that the administration of valproic acid to pregnant mothers can cause fetal developmental problems, such as autism spectrum disorder (ASD) (Miyazaki et al, 2005).
Can its administration to an ...
2
votes
1answer
101 views
Please explain the algebraic reasoning in this textbook
I am reading Dennis M. Brown “Drug Delivery Systems in Cancer”. On Page 29 when referring to monotonic increase or decrease of n (being the number of cells n(t) I believe) then how are they getting
...
6
votes
2answers
212 views
Are there beneficial compounds in cigarette smoke?
The UKPDS 50 study suggested that smokers experience lower rates of diabetic retinopathy
Somewhat counter-intuitively, smoking status was inversely related to the development of new lesions and to ...
6
votes
1answer
50 views
Barrett's esophagus (BO) and proton-pump inhibitors (PPIs)
I have come across an interview with a European gastroenterologist (apparently from 2006) where he argues that in cases where a reflux disease does not cause typical symptoms even the presence of a ...
2
votes
1answer
56 views
How (un)suitable are veterinary products for human health?
We've all seen movies in which gangsters are treated by (paid or coerced) veterinarians in order to avoid law enforcement in hospitals. How bad are animal-grade pharmaceuticals for human health, in ...
1
vote
1answer
34 views
Longterm effects on DNA of aciclovir
Since aciclovir works by decreasing the production of the virus's DNA, one might fear that it also damages DNA of healthy cells. I know that it is usually said that aciclovir doesn't affect healthy ...
4
votes
2answers
101 views
Why does acne get worse during the first two weeks of treatment with isotretinoin?
I've heard and read from multiple sources that acne gets worse during the first two weeks of treatment with isotretinoin, but I haven't been able to find an explanation as to why this happens.
From ...
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0answers
64 views
Prozac, Ritalin and Valium..together [closed]
There is a certain movie in which one the characters takes Prozac, Ritalin and Valium..together. When someone asks him what it is, he states the composition, adding "Breakfast of Champions".
Being ...
5
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1answer
99 views
Why is hydrocortisone mixed with clotrimazole in anti-fungal medication?
Considering clotrimazole is the active ingredient killing the fungus.
2
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1answer
33 views
What does JP mean after a medicine/compund name?
I take Methycobalamin (Vitamin B12) supplements.
I noticed the tablet packaging reads "Each Sugar coated tablet contains Mecobalamin JP 500 mcg"
What does JP mean here?
Thank you.
0
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0answers
37 views
Why aspirin dose is reduced in gastric achlorydia?
Aspirin remains in unionised form in acidic $pH$ but this unionised form is a diffusible form which is helpful in absorption across lipid membrane.
My reasoning almost tries to contradict the ...
2
votes
1answer
52 views
Do all Eye drops for dry eyes contain steriods?
Do all eye drops for the dry eyes contain steroid?
How can you check if the eye drops include steroids in it?
3
votes
0answers
44 views
How much does what you eat impact medication absorption? [closed]
Some medications advise being taken with food, generally either to prevent stomach irritation as is the case with NSAIDs, or to improve absorption, as is the case with numerous other medications.
How ...
3
votes
0answers
73 views
Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion?
Must one take anticoagulants lifelong after stenting of deep veins with a non-thrombotic lesion, for example, aorto-venous conflict (May-Thurner syndrome)?
Or is it enough to take anticoagulants only ...
3
votes
1answer
62 views
Is cannabidiol safe to treat depression of a patient with a schizoaffective disorder?
According to wikipedia CBD might be useful as an antidepresant:
"CBD has been shown to act as a serotonin 5-HT1A receptor partial
agonist,[33] and this action may be involved in its
...
5
votes
2answers
227 views
Why does Melarsoprol have to be injected in glass syringes?
A WHO document, contains the statement
[Melarsoprol] injections must be performed using glass syringes.
Why is this the case?
2
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0answers
22 views
Meaning of “potential pharmacogenetic characterisation might also be evaluated so that these syndromes are treated at an earlier age.”
This could be offtopic because this might be just a case of sloppy phrasing and a case of "asking to guess what the authors really meant". A quote from an abstract (GTP-cyclohydrolase deficiency ...
3
votes
1answer
56 views
Why do doxycycline pills also contain lactose?
Prescriptions in the UK contain doxycycline as doxycycline hyclate. They are also listed as containing lactose.
Why is the lactose helpful?
4
votes
1answer
148 views
Migraines and tryptophan
One theory about migraines is that it is triggered by dropping serotonin levels.
One medication, sumatriptan, acts by raising serotonin acting as a reuptake inhibitor.
Since tryptophan is converted ...
