Questions tagged [medications]

Questions related to intake, use, safety, side effects, pharmacokinetics, or any other aspect of a drug prescribed by a physician.

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1answer
31 views

Why do corticosteroids have few kidney-related side effects?

Prostaglandins are involved with promoting various renal functions. Therefore, NSAIDs, like indomethacin which inhibits protaglandin formation through COX enzyme inhibition, tend to have many side-...
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Does Nortiptyline stop migraines or just the feeling of the migraine occurring? [closed]

Does the medication actually stop the migraine from occurring or does it just stops the feeling of the migraine occurring?
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7 views

What's happening with Nexium discoloration? [closed]

My baby is prescribed Nexium for GERD. It comes in small packets of powder which are dissolved in water. I've noticed that if we forget to immediately rinse the measuring tube there will be a very ...
3
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1answer
33 views

Why is prothrombin time used to monitor warfarin and not aPTT?

Warfarin is said to change prothrombin time (PT) but not activated partial thromboplastin time (aPTT) (for practical purposes at least anyways, not really sure). But looking at the mechanism of action ...
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1answer
47 views

Is it useless to drip Vitamin D drops on your tongue? [closed]

One celebrity doctor in my country says that Vitamin D can be absorbed only in the small intestine and that dropping Vitamin D drops on your tongue is therefore useless, because most of the liquid ...
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23 views

Have any conclusions been made regarding the interaction of Covid-19 and ACE inhibitor medications? [duplicate]

About two months ago, I started to see articles appear regarding the potential interactions between ACE inhibitor medications (commonly used to treat high blood pressure) and the severity of Covid-19 ...
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3 views

What is the difference between clinical study and clinical trial study? [closed]

My question is that can every study that is focused on evaluating the effect of a drug in human be regarded as clinical trial study? For example: A study is conducted to find the effect of Azadirachta ...
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What exactly is the meaning of “No doping” sign on a drug package?

I noticed a "No doping" sign on the back of a pack of Dopamine HCl ampoules. It looks like this: I was wondering what is the purpose of this sign. I am guessing that it means that the drug should not ...
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1answer
47 views

Does Ivermectin treat COVID-19 coronavirus infection?

Does the anti-parasitic Ivermectin work in actual human studies versus the Petri dish in vitro studies, when treating coronavirus COVID-19 infection? And if so, is it safe in humans? An in vitro ...
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1answer
50 views

What is the difference between Dry cough, Wet cough, Chesty Cough, Barking cough?

I am doing some research on cough sounds but my background is not health sector and I am facing issues to identify the correct type of cough. I have two doubts : Is chesty cough Wet cough? Is ...
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How is Lopinavir + Ritonavir expected to stop COVID-19?

There are four drugs being tested for effectiveness against COVID-19 in the SOLIDARITY trial. Three of them have obvious potential mechanisms of action: Remdesivir is an RNA polymerase inhibitor. ...
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1answer
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Why are multiple courses of isotretinoin necessary to treat acne?

The following guidances don't detail why multiple courses are more efficacious? Aug 21 2019 PRODUCT MONOGRAPH on Accutane, Hoffmann-La Roche Limited, p. 13 of 36. Effects of multiple courses of ...
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2answers
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What are the special medications to treat Covid-19?

We know there is no cure for Covid-19 (currently) and the treatment focuses on managing symptoms as the virus runs its course. The main symptoms of Covid-19 are -Fever -Cough -Shortness of breath ...
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Study type/design used in an coronavirus article?

I came across an article given here While I was reading the article, I wasn't able to find the study type/ design? Can you please help me find out what is the study design/type here? Meaning we ...
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2answers
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Are there any central trackers for COVID-19 trials?

There are several aggregate central trackers for the spread of COVID-19. Like this one, for example. Is there anything similar for trials? Or trials in the pipeline? Either vaccines or treatments?
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1answer
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Can oseltamivir shorten the duration of COVID-19 and inhibit replication and transmission of the SARS-CoV-2 (2019-nCoV) virus?

Oseltamivir (tamiflu) is an antiviral medication used to treat and prevent influenza A and influenza B (flu). It is said (https://www.ncbi.nlm.nih.gov/pubmed/27660842) to reduce symptom duration even ...
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1answer
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How do huge computer simulations help in medical research?

I found the there is a project Folding@home to fight against COVID-19. As far as I understand, it uses huge amount of computing power to find a cure. Why do we need such a huge number of potential ...
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19 views

Tilt table test and beta blockers

Is tilt table test indicative with beta blockers for dysautonomia diagnosis? Or is it require drug withdrawal?
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1answer
35 views

Side-effects or other medical conditions for diabetic patients

I have a database of diabetic patients and their medication/lab test data as well. 1) I am planning to run a simple analysis like finding out incidence rate example: amongst the T2DM patients that I ...
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2answers
51 views

T2DM medication treatment pathway

I am looking at the T2DM medications specified here and have a few questions about them. 1) Why don't I see drugs like Troglitazone, Tolazamide, Acarbose, Acetohexamide, Chlorpropramide, Miglitol? ...
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1answer
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Rationale for Pilocarpine instillation after retrobulbar haemorrhage

BACKGROUND: Retrobulbar haemorrhage may occur due to retrobulbar block. Immediate pressure bandage after instilling one drop of 2% pilocarpine and postpone of operation for a week is advised. What is ...
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25 views

T2DM diagnosis vs disorder due to T2DM diagnosis?

I have a database of diabetic patients. Mostly 80 % are T2DM patients. Now I would like to identify the T2DM patients based on their conditions reported. I mean when patients visit hospital (diabetic ...
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1answer
36 views

How to interpret diabetic complications?

I have a database of diabetic patients. Mostly 80 % are T2DM patients. Now I would like to identify the T2DM patients based on their conditions reported. I mean when patients visit hospital (diabetic ...
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33 views

Is there a greater benefit as as to why an ob-gyn will prescribe a birth control with higher risk of Venous Thromboembolism?

It is already known that combined oral contraceptive (COCs) pills increase the risk of serious complications such as Venous Thromboembolism. However there are other options that have relatively much ...
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1answer
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General purpose vomit response control?

Is there a general purpose antiemetic for vomit response control? Many vomit control solutions are focused on specific causes for the vomiting. Some common causes of nausea/vomiting: Cancer ...
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51 views

What is the process of calculating if a molecule is helpful and/or harmful to an organism?

From reading about pharmacology through the years I synthesized from my own prior research that What is the process of calculating if a molecule is helpful and/or harmful to an organism is this: A ...
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1answer
34 views

How does Diabetic specialist clinic work?

I am from IT domain and would like to seek some help on certain medicine related questions I would like to know how does Diabetic specialist hospital/clinic work for Diabetic patients when compared ...
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1answer
44 views

What is daily sedation interruption for ventilated patients?

I was reading about ventilator bundle here and came across this term called Daily Sedation Interruption. Does this term mean break in giving the sedation drugs? How can this help in reducing the ...
2
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1answer
57 views

T2DM Fasting glucose level - extreme cases

I am working on clinical data analysis and currently dealing with T2DM patients. When I look at their Fasting glucose level readings, I see that their values range from 0.9 mmol\L to 64 mmol\L The ...
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1answer
40 views

Do patients with VAE stay in ICU for longer time?

I was reading online that people when put in ICU under mechanical ventilation, can develop Ventilated Associated Events. What I would like to know is: does the stay in ICU increase for people who ...
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1answer
68 views

Fluid balance range for human

I am working on clinical data analysis with patients from icu who are mechanically ventilated and in ICU for 4 or more days. Currently I tried to calculate their fluid balance based on the input and ...
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54 views

What are the main problems with non-injectable ways to administer molecules into the human body?

From past reading in various sources there seems to me to be many ways to administer molecules into the human body without injections that cause tissue trauma but that these ways generally aren't ...
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1answer
31 views

Drug dosage in pharmacology [closed]

Please give a overview about how the dosage of a particular drug (e.g. ciprofloxacin) is determined in pharmacology?
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1answer
62 views

Why did it take so long to notice that Zantac had carcinogenic ingredients?

Why did it take so long to notice that Zantac had carcinogenic ingredients? Sanofi is recalling the popular heartburn drug Zantac. The generic name for the drug is Ranitidine. Apparently, the ...
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1answer
113 views

Why many usually-very-painful medical processes aren't done under conscious, generally painless-painkilling?

Many usually-very-painful medical or medical-defined processes such as: Hair transplant Lip botox Fecal impaction removal Dental cleaning (stone removal) Aren't being done under conscious, generally ...
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Why/how are some drugs nephrotoxic?

I want to know the (more or less) exact mechanism by which specific nephrotoxic medications damage the kidneys. For some drugs it seems relatively intuitive that they interfere with the function of ...
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1answer
1k views

Is there an interaction between methamphetamine and dental anesthetic?

According to the sign shown in this post on Reddit, using methamphetamine and dental anesthetic together is lethal. If you use Methamphetamines (Crystal Meth, Crank, Speed, Glass, Tweak, Yaba)...
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Ergotamine v Sumatriptan for migraine without aura

A randomized, double-blind comparison of sumatriptan and Cafergot in the acute treatment of migraine. The Multinational Oral Sumatriptan and Caferg... - PubMed - NCBI It is concluded that oral ...
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35 views

Why was Ergotamine (trade name: Cafergot) discontinued in Canada and UK?

My mom in HK was prescribed Ergotamine, but I'm unnerved discontinuation in Canada and UK! Something wrong with it? Asked 13 Oct 2012 by lucyglitters i live in the uk and i've been taking it for ...
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1answer
35 views

what is the advantages (for patients) in delayed and extended release drugs?

What are the advantages for patients between extended and delayed release drugs? i understand the difference between these two drugs, but i want to know the advantages to the patients itself between ...
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0answers
24 views

Lucidity and pain reduction link [closed]

I am a layman, so this is no doubt an overly broad and probably dumb question, but if someone will humor me and attempt to answer, I would greatly appreciate it. Why is it that studies tend to show a ...
2
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1answer
39 views

Is Racemic Epinephrine Compatible as Treatment For Anaphylaxis?

I am writing a work of fiction and want it as scientifically accurate as possible. In theory, is racepinephrine (the active ingredient in Asthmanefrin) compatible as an emergency replacement for ...
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1answer
51 views

Citrate vs EDTA

What is the difference between the use of «citrate» and «EDTA» as an anticoagulant in medicine (I know that each one is used for some dosages but not the other, but I need to know why)?
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What is the expected life span of vascular stents?

What is the expected life span of vascular stents? For example: Universal (coronary/venous) stent WALLSTENT-UNI Boston Scientific, metal: nitinol = titanium + nickel. How many pulsating contractions ...
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0answers
62 views

Can blood flow destroy part of the metal stent in 10 to 40 years?

If a part of the metal stent has not grown into a vessel, can this part of the stent be washed out by the blood flow in 10 to 40 years (theoretically)? Also are such cases known that blood flow ...
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3answers
238 views

Why is it that psychoactive drugs tend to be dangerous?

I'm personally not a big fan of recreational drugs, illicit or otherwise, but there's an interesting medical question buried in their use. Why is it that substances that make you feel good tend to be ...
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1answer
57 views

How are the administration times for medications determined?

Many prescribed medications give a rate at which to apply the medication, and "over-the-counter" medications often have a minimum time period between dosages the users of the medications are not to go ...
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1answer
112 views

Why isn't paracetamol routinely combined with n-acetylcysteine?

Whether it's acute large dose paracetamol or long term regular dosage of paracetamol usage, it is a problem for the liver, ototoxic and even potentially life-threatening. While one might question the ...
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1answer
61 views

Is it dangerous to administer valproic acid to an adult with an autism spectrum disorder?

I read that the administration of valproic acid to pregnant mothers can cause fetal developmental problems, such as autism spectrum disorder (ASD) (Miyazaki et al, 2005). Can its administration to an ...
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1answer
101 views

Please explain the algebraic reasoning in this textbook

I am reading Dennis M. Brown “Drug Delivery Systems in Cancer”. On Page 29 when referring to monotonic increase or decrease of n (being the number of cells n(t) I believe) then how are they getting ...

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