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Questions tagged [genetics]

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Genectics differencces between veg vs non-veg [closed]

I have one doubt from my childhood. The person who is strictly vegetarian by birth, and another person who is non-vegetarian by birth, are their genetics are totally different or same?
D. S.'s user avatar
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3 votes
1 answer
364 views

Why is gene therapy more effective in children than in adults, if proteins can be recreated once the genes have been corrected?

As someone with significant bilateral hearing loss for several years, I was really disappointed to learn that the Progenitor Cell Activation procedure from Frequency Therapeutics had failed horribly, ...
HeavenlyHarmony's user avatar
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0 answers
44 views

Does drug resistant cancer eventually lose its drug resistance?

Does a cancer cell population eventually lose its drug resistance, if you give it enough time? For example, if you take some cancer cells in vitro, make them drug resistant to a certain drug, then ...
Some Guy's user avatar
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3 votes
0 answers
73 views

Partial UPD in Diamond-Blackfan syndrome patients

I got the following question on a practice exam: "In a 9-year-old patient, a diagnosis of Diamond-Blackfan syndrome is made. Exome analysis reveals the presence of a pathogenic de novo ...
Sara's user avatar
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3 votes
0 answers
102 views

Why can't Asian flush be treated in a similar way to lactose intolerance?

I have been reading about the Asian flush, which is caused by a histamine reaction to a toxic byproduct of alcohol metabolism, acetaldehyde. Some individuals are able to suppress the histamine ...
Jacob T's user avatar
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1 vote
1 answer
51 views

How to determine the chances of inheriting an autosomal recessive disease if the carrier status of parents is unknown?

My question is about determining the carrier chances of an autosomal recessive disease without actually testing for it and to validate my understanding about autosomal recessive disorders. In order to ...
Bob Ortiz's user avatar
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1 vote
1 answer
72 views

How did hereditary diseases originally start?

(To preface this, I've 0 knowledge of medicine) If diseases such as Huntington's are hereditary and you can't develop/catch them later in life, how did the original person in the family bloodline get ...
JamesM's user avatar
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1 answer
83 views

Decide parent and child from DNA

Given the DNA of a parent and the DNA of a child of the parent, is it possible to tell which DNA belongs to the parent and which to the child? I've tried looking this up online, but could only find ...
domotorp's user avatar
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2 votes
1 answer
50 views

Is there any statistical overlap between people who identify as non-cis and people who have an unusual number of sex chromosomes?

The title kind of says it all. I'm wondering if there has ever been a study of non-cis identifying individuals to see how many have sex chromosomes that were something other then XX or XY and if so ...
dsollen's user avatar
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2 votes
0 answers
50 views

May subclinical Acatalasemia cause premature gray hair in an otherwise healthy human and if so, how is it normally treated?

It was written in the current version of the Wikipedia article Catalase: Low levels of catalase may play a role in the graying process of human hair. Hydrogen peroxide is naturally produced by the ...
Georgelucas's user avatar
1 vote
1 answer
71 views

What is cloning used for?

I am reading an article about a novel splice-site mutation in the ELN gene that suggests an alternative mechanism for vascular elastinopathies. Below, there is one part of the article which refers to ...
user108385's user avatar
4 votes
1 answer
9k views

Child has A+ blood group when both parents are O+

Based on my understanding of blood group tables, such as the one below a child can only get O blood group when both parents have O as their blood group. In a close relative's case, while her parents ...
Chethan S.'s user avatar
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1 answer
86 views

Is there a real life genetic disorder that can be considered as the opposite of achondroplasia?

Achondroplasia is a form of dwarfism that is characterized by short limbs, normal-sized abdomen, torso, and neck, and macrocephaly. Could there be a form of gigantism that is characterized by long ...
mammifereviolet4694's user avatar
4 votes
1 answer
1k views

What is the difference between mutation and variant?

What is the difference between mutation and variant? News reports last week called Omicron a mutation of SARS-CoV-2; but this week they are calling it a variant and they are adding that it has a lot ...
Rahul Khimasia's user avatar
-3 votes
2 answers
66 views

What is the probability that a couple has no common defective gene?

If a couple has no common defective gene, they can produce a big healthy population from just two people, right? What is the probability that a human couple (especially of different races) has no ...
porton's user avatar
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0 answers
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Result of Inclusion-cells in the I-cell disease

What happens to the cells once the body doesn't have the lysosomal enzymes to degrade lipids and such. Inclusion bodies appear, but how do they provoke so many symptoms like hepatomegaly motoric delay ...
Basho's user avatar
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3 votes
1 answer
104 views

Is the code from the mRNA vaccine executed by the cells as a one-off? [closed]

Is the code from the mRNA vaccine executed by the cell that has taken it up as a one-off or does the cell produce the spike proteins endlessly (like a programming loop) until the cell is killed by the ...
Lukasz Korzybski's user avatar
10 votes
2 answers
527 views

Why is the new mRNA vaccine unable to modify human DNA?

One of the most common worries expressed against the new coronavirus vaccine is that, supposedly, injecting mRNA into a cell has the potential to alter the human genome. I am constantly bombarded by ...
gaazkam's user avatar
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1 vote
0 answers
34 views

Who's RNA does the rRT-PCR test for SARS-CoV-2 target?

The official guide for laboratory testing for coronavirus disease in suspected human cases by the WHO explains the procedure for testing a sample. On page two it states that the test is based on ...
bitmask's user avatar
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1 answer
33 views

What does NKX2-5 do?

Where is the gene 'NKX2-5' located and what is its function? How is it relevant to developmental disorders?
Andrew's user avatar
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Why do common diseases tend to be polyfactorial, while rare diseases often involve a single gene?

This answer by xiota to Why do gene therapies so often target rare disease? states: Common diseases tend to be polyfactorial, while rare diseases often involve a single gene. Many involve just a ...
Franck Dernoncourt's user avatar
0 votes
1 answer
68 views

COVID-19 and genomic sequencing

The most common explanation given for the large amount of COVID-19 infections in Victoria (Australia) is that it has been transmitted from inbound people in quarantine via security guards to their ...
Ben Martin's user avatar
0 votes
1 answer
49 views

Is it possible that there are some people who cannot get Type 2 diabetes?

I have read this answer to a different question which discusses a theory of the cause of type 2 Diabetes. It describes insulin resistance leading to a runaway positive feedback loop. The answer also ...
Ryan1729's user avatar
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3 votes
1 answer
191 views

Is being of direct African ancestry a risk factor for severe COVID-19 disease?

In the initial outbreak of COVID-19 in Asia, the populations affected were fairly homogenous though ethnicity data isn't available from the studies published from China. However, Chinese are ...
Graham Chiu's user avatar
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2 votes
1 answer
133 views

What are the genetic predispositions, if any, for covid-19?

What are the genetic predispositions, if any, for covid-19? For example, https://www.express.co.uk/news/science/1258244/Coronavirus-symptoms-COVID19-susceptibility-genetic-transmission-latest-...
Franck Dernoncourt's user avatar
0 votes
0 answers
26 views

Pedigree disease risk calculation IRL - how difficult/expensive?

The probability of a child being affected by genetic diseases like Spinal muscular atrophy or Canavan disease (and many other) depends solely on the parents being carriers of such disease. Suppose ...
Alexander Mikhalchenko's user avatar
1 vote
0 answers
17 views

Why can't we use genomic libraries for gene therapy or making transgenic animals

My text says we have to use expression libraries (cdna libraries) for constructing transgenic animals or for gene therapy, Now I can't understand why genomic libraries can't because for gene therapy ...
Physicsapproval's user avatar
1 vote
0 answers
32 views

How do melanin or pigment related genetics from Vitiligo patients compare to or differ from Albinism patients?

The definition of Albinism is: Albinism is a congenital disorder characterized in humans by the complete or partial absence of pigment in the skin, hair and eyes. 1 The definition of Vitiligo is: ...
Bob Ortiz's user avatar
  • 1,039
3 votes
2 answers
156 views

Technology prospects for genome sequencing at home and data protection

Ever since the end of the Human Genome project we have been witnessing the steady advance of genome sequencing technology and the decline of the price required to perform it. This lead to the advent ...
healtech's user avatar
3 votes
0 answers
82 views

Is vitiligo inherited from one generation to a later one?

There seem to be many testimonies on the internet that suggest that vitiligo is heritable 1. According to a Quora answer 2, there is apparently a 5% chance of transferring vitiligo to your kids. Yet, ...
Bob Ortiz's user avatar
  • 1,039
7 votes
1 answer
223 views

Why is Down Syndrome so common relative to other chromosomal conditions?

According to the National Down Syndrome Society, Down Syndrome is the most common chromosomal condition, with roughly one in 700 children born in the United States affected. The genetic disease ...
TheEnvironmentalist's user avatar
2 votes
1 answer
77 views

What effect would a sperm containing XX have on a ovum and fetus?

So this is just a random thought I had, while writing a story, but I assume this is likely impossible currently, and likely in the far future aswell, but let's assume a scenario where the body that ...
MartinArrJay's user avatar
2 votes
1 answer
72 views

"Disease X is allelic with disease Y" - what is the meaning of "allelic" here?

From a review on Cerebral Folate Deficiency: A disorder initially reported as folinic acid responsive epilepsy was subsequently shown to be allelic with PDE – both are caused by biallelic mutations ...
CowperKettle's user avatar
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0 votes
0 answers
106 views

What is the difference of a physician specializing in cytology and a physician specializing in medical genetics?

Is cell biology much broader than just genetics or am I conjecturing nonsense? Who is the specialist in the molecular biology of cancer? I am a cancer patient since 16, a medical student aiming for ...
George Ntoulos's user avatar
3 votes
0 answers
39 views

Is lean non-hyperandrogenic polycystic ovary syndrome genetic?

I read many papers that address the genetic factor of polycystic ovary syndrome (PCOS). But all the papers I have been through focus on classic PCOS with hyperparathyroidism and insulin resistance. I ...
megan m's user avatar
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2 votes
0 answers
52 views

Online Genetic Test Repositories

I've found out that NCBI's Genetic Testing Registry database holds quite a large collection of genetic/genomic tests available. However, it is a database where producers/researchers submit their ...
ekokrek's user avatar
  • 21
7 votes
1 answer
136 views

Is it possible for obesity to occur as a result of medical conditions and not just over-eating?

I am not obese myself as I've always been interested in sports since childhood, and put effort into living a healthy and active lifestyle. However, obesity is clearly a growing issue worldwide (no pun ...
Will Appleby's user avatar
5 votes
1 answer
134 views

Revealing a murderer based on a genetic condition

I'm writing a story, in which the detective will recognize a prescription for the victim is for relief of some genetic condition. He then claims that another character was the murderer because she ...
IchabodE's user avatar
  • 151
3 votes
0 answers
260 views

Relation between phlegm and hair loss [closed]

I know hair loss can be created by many reasons such as genetic, air pollution and so forth. But, I want to know whether there is a relationship between hair loss and removing phlegm from throat ...
ThisIsMe's user avatar
2 votes
1 answer
84 views

23andMe DNA Test is reliable?

Does the 23andMe DNA Test is reliable and worth to get ? Or there is nothing like the actual physical dna tests at laboratories. Does 23andMe DNA Test provide the exact information provided by ...
alim1990's user avatar
  • 273
2 votes
1 answer
112 views

Strange hair growth behavior

My hairs started to grow white when I was about 18. After that, I notice some of them grow black again, but mostly they are turning into white. At this age (24 y/o) almost half of my hairs are white....
Johansson's user avatar
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2 votes
0 answers
38 views

Where can I find information about this deletion?

Consider the following chromosomal formula 46,XX,del(7)(q11q36)[12]/46,XX[13] It indicates that the patient has 46 chromosomes, is a female and has a deletion on the long arm of chromosome 7 ...
Remi.b's user avatar
  • 483
2 votes
1 answer
198 views

on what metabolism depends

Some people have fast metabolism (high basal metabolic rate), but some slow one. Usually it's high for men and decreasing with age. And fast metabolism is considered as good one, because it keeps ...
Alexan's user avatar
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3 votes
0 answers
52 views

Hyper Magnetism?

Didn't know where to post this one but this forum seemed the most suitable. So about a year ago I've discovered that my mom can "glue" metalic spoons and forks to her hand and mechanic watches slow ...
Harry Zalessky's user avatar
4 votes
1 answer
792 views

Can viruses be inherited?

In theory, any virus capable of infecting germ cells can plant its genetic load into the sperm/ova that will eventually become offspring. So are most viruses inheritable? Really, if your parents ever ...
TheEnvironmentalist's user avatar
0 votes
1 answer
4k views

Are dimples and cleft-chins (aka dimple chins, butt chins) genetic?

Are dimples and cleft-chins (aka dimple chins, butt chins) genetic? How rare are cleft chins or dimples?
Pills N Pillows's user avatar
1 vote
0 answers
6 views

Can Steinert syndrome be developed passed the thirties?

Can a person carrying the gene responsible of developing the Steinert syndrome start suffering it passed his/her thirties? What are the chances of developing the syndrome if a person carries that gene?...
Claudi's user avatar
  • 111
2 votes
0 answers
50 views

Determination of probiotic regimen based upon genomic profile?

I have been amazed at the accurate and pertinent results from some services such as NutriHacker (via data from 23andMe.com or DNA.Ancestry.com). This has allowed me to take my nutritional ...
ylluminate's user avatar
6 votes
1 answer
102 views

Is it possible to not have BRCA1 and BRCA2 genes?

I had DNA analysis from 23andMe, however in the results there was no information about the BRCA1 and BRCA2 genes. Does that mean that I do not have these genes? Does every human have these genes, or ...
nikolaos vougiouklis's user avatar
5 votes
1 answer
228 views

Rheumatoid arthritis heritability

Is there any scientific information available on how likely it is that a child with one parent with rheumatoid arthritis will have the same condition? I know there's probably not going to be any hard ...
YviDe's user avatar
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