41 votes
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Why is thalidomide a current drug on the market?

Because leprosy and multiple myeloma are conditions for which other treatment options are limited. All treatments have side effects, some more debilitating than others. The trick with pharmacology is ...
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  • 526
37 votes
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Why should I avoid milk when on antibiotics?

Products high in calcium and magnesium should not be taken at the same time as antibiotics of the tetracycline (tetracycline, doxicycline, etc.) class, and milk should also be avoided with the ...
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29 votes
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Why do doctors prescribe steroid tablets even though they know the side effects?

I think a missing bit of information that might help you get a better sense of this practice is: steroids are miracle drugs. OK, that was in jest - no miracles here. Truth be told, though, if there ...
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  • 4,355
20 votes
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What can you learn from the parts of the name of a drug?

Stems and affixes tell you the class of drug (and sometimes other properties). Drugs in the same class work in a very similar way, so therefore you can tell what other drugs it's related to. This is ...
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  • 5,693
14 votes
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Why is it so much harder to swallow pills than it is to swallow food?

The human (and other animals) upper digestive tract is 'designed' to ingest relatively large (compared to most pills), soft, moist boluses. The muscles of the tongue and pharynx can propel these ...
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14 votes

Is there any evidence for health benefits from cannabis?

Marijuana as medicine Its usage in modern times is controversial, however studies of chemicals in the plant (cannabinoids such as THC, CBD) has lead to two FDA-approved medications and more research ...
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  • 4,697
12 votes
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Do we have a general system of class of drugs that a layman can understand?

There is no need for any person to learn any drug taxonomy, unless this person is creating or extensively using clinical or pharmacological documentation. I don't doubt that somewhere, a single ...
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  • 2,770
12 votes
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Why does the weight matter when consuming a certain amount of a specific drug?

I think the centre of confusion for you is this question: If the active substance finally goes to the brain, where is the weight's role in this process? The thing is, when a substance has a ...
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  • 2,803
12 votes
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What are the best ways to increase fertility?

I will try to answer your question by using another perspective (risk factors for infertility). MALE Among the main causes of male infertility, "idiopathic" causes (ie not du to endocrine problems, ...
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11 votes
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Does Benadryl (=diphenhydramine) lead to tolerance? Can I use it to help with sleep?

First generation H1-antihistamines (such as diphenhydramine = Benadryl) are well known for their sedative effects explaining their limited use in patients with allergic rhinitis. Several ...
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10 votes
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How exact are the times for how long to wait between pills?

Good question though a broad one! Well, it all depends on the 'pill' or 'medicine' you are on. Different medicines have different half-lives. And 'half-life' is the factor that mostly decides the '...
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  • 559
9 votes
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What makes Cialis cure Erectile Dysfunction permanently?

Is the above result believable? The results show treatment of symptoms of ED, if the medication stops then the symptoms will come back. So yes the results are believable one could say, but they are ...
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  • 2,952
9 votes
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Has there been any medical studies as to whether drinking a 'Hot Toddy' can help to ward off or to help heal someone who has COVID-19?

To my knowledge no, nobody has specifically studied this in relation to COVID-19. I can't really prove the negative but I tried a few combinations of search terms in to PubMed and came up with nothing....
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  • 1,252
8 votes
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Can an antipyretic (I.e. Aspirin) lower normal body temperature?

It is not possible. The regulation of human body temperature (thermoregulation) is very subtle. Wikipedia article about thermoregulation contains a very nice graph about that mechanism. The labels ...
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  • 2,322
8 votes
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Is there a technical term for the phenomenon known as "brain zaps"?

Antidepressant Discontinuation Syndrome Affects approximately 20% of patients who experience abrupt discontinuation of an antidepressant that has been taken for at least 6 weeks. There are a myriad ...
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  • 346
8 votes

Alternative to caffeine - same effects, different chemical

There is a substance similar to caffeine - theobromine, found in cocoa. They are chemically similar, and have some similar effects*: the formula above shows theobromine, and this is caffeine. Of ...
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  • 2,803
8 votes

How to get rid of erectile dysfunction?

Before going directly into the topic, firstly, it is necessary to comprehend the mechanism of erection, because small fault due to different factors in the mechanism gives rise to its dysfunction. ...
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  • 725
8 votes
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Is the drug's effectiveness directly proportional to the half life formula?

Two key serum concentrations to know about in pharmacodynamics and pharmacokinetics are the Minimum Effective Concentration (MEC) and Toxicity Concentration (TC). Some medications have stronger ...
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  • 5,693
7 votes
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Does keeping different types of medications in one pill bottle affect their quality?

No, this does not alter them, or make them less effective. There are problems with a scant amount of medicine crumbling, as you've noticed. The only real concern I'd have for anyone doing this is ...
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7 votes
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Can oral contraceptives prevent ovarian cysts from forming?

[I]s it logical/healthy to take in oral contraceptives on a regular basis even if one is not engaged in intercourse? There are several reasons to take oral contraceptive pills (OCPs) that have ...
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7 votes
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How do anti-gas remedies work?

I cannot speak of all possible gas medicines. But there is a class of them which is indeed low risk and over the counter. These are silicones, and they work in a purely mechanical way, not getting ...
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  • 2,770
7 votes
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Topical nifedipine cream and hypotension

Nifedipine is a dihydropyridine calcium channel blocker. As you point out, it is used via oral administration for treatment of hypertension. Its effects are mediated primarily by blocking voltage-...
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  • 4,355
7 votes
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Use of antibiotics and the night gap

There are very few (but there are some) medications that need to be taken at very strict time intervals; early drugs for AIDS needed to be taken even in the middle of the night. No one expects four ...
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7 votes

Why is medicine used to treat symptoms which are our body's way of telling us something is wrong?

I presume you're taking the teleological view that symptoms are "good" and have a beneficial (if not fully understood) purpose, and therefore should not be messed with. That is a cognitive bias (a ...
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7 votes
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Tips to improve the sleep during the night

You should keep an eye on the sleeping environment's temperature and restrict the amount of light entering the space you sleep in. Eye masks are a cost-effective solution to reducing excessive light ...
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7 votes
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Top medications to treat symptoms of Lupus?

Your question is difficult to answer (but still interesting) because lupus is a highly heterogeneous condition which can present various symptoms and organ involvement. Choice of therapy will be ...
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7 votes
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Fact or Hoax : Unconventional method of saving human life from stroke?

My Grandmother died of a ischemic stroke (TIA followed by blockage) after weaning herself off of blood thinners because she didn't "need the medicine". Huge issue with his advice - the large majority ...
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  • 1,089
7 votes

How can I learn to swallow pills without gagging?

If you are able to swallow pills but find it difficult, the following tips will help: take a sip of water before putting the pill in your mouth, and drink more water after putting the pill in as well ...
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  • 3,744
7 votes
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Where does Ibuprofen inhibit COX-1, and what is its MoA?

I'm not clear why you're asking this as this information is readily available unless I missed something in your question. As for anticoagulant activity, my recollection is that if anything Ibuprofen ...
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