Questions tagged [organ-transplant]

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4
votes
1answer
44 views

Can tacrolimus creme cause tacrolimus toxicity?

Tacrolimus is a medication given to patients who underwent organ transplantation. Increased serum level of tacrolimus may cause overdose symptoms. Apparently the normal tacrolimus serum level is ...
0
votes
1answer
35 views

What’s keeping us from growing organs from stem cells?

If we know how to cause embryonic stem cells to differentiate into different tissue types, and we know how embryonic development turns those tissues into organs, why can’t we yet grow entire human ...
0
votes
0answers
15 views

What is the longest kidney-exchange cycle yet?

What is the longest kidney-exchange cycle yet? I.e. the longest cycle of simultaneous surgeries "donor1-recipient2-donor2-recipient3 ... donorXX-recipient1" I am preparing a lecture on the Roth-...
3
votes
1answer
40 views

Why can’t we just transplant donor organs into pigs to preserve them?

I’m a newbie and utterly unfamiliar with biomedicine, but I’ve been reading a few scientific articles recently and a question has been nagging me ever since. So apparently preserving donor organs ...
1
vote
0answers
41 views

Effects of Garlic on Tacrolimus via CYP3A4

Garlic is said to be an inducer of CYP3A4, Tacrolimus is metabolized by CYP3A4. The list of drugs (and some foods) interacting with Tacrolimus is long but nowhere I found a note on garlic. Grapefruit ...
2
votes
0answers
48 views

Is it technically possible to replace aging body part and live forever? [closed]

I heard that iPS cells can be used to make some human organs (Takebe, et al. 2013). If we make young organs using regenerative medical techniques and replace aging organs with them, can we live ...
1
vote
0answers
24 views

What could cause a stroke soon after a lung transplant? Is it even known?

Recently a youtuber died of a thrombotic stroke a week after a lung transplant operation. Skimming over abstracts on Pubmed, it appears that strokes and more generally thrombosis is a frequent ...