Quoting a line from Robbins and Cotran Pathology,
"Renal ablation FSGS, a secondary form of FSGS occurs as a complication of glomerular and non glomerular diseases...striking examples include unilateral agenesis"
Well since unilateral agenesis is akin to having a single functioning kidney, does it not make sanse that some of the remainging glomeruli overtime will have to undergo hypertrophy and eventually sclerose?
Does that happen? I'd love to be pointed towards the literature on this if possible.