Questions tagged [stem-cells]
The stem-cells tag has no usage guidance.
18
questions
4
votes
1
answer
106
views
Can we develop milder drugs to eliminate hematopoietic stem cells?
Eliminating preexisting hematopoietic stem cells (HSC) is a necessary step before HSC transplant. Traditionally this "adjuvant" treatment is performed by means of high dose chemotherapy and ...
- 143
0
votes
0
answers
21
views
Why isn't there a notable "graft versus host" effect in lymphoma?
In other words, why don't we use allogenic hematopoietic stem cell transplantation (in general) for lymphomas? (with the exception of being occasionally used in highly selected lymphoid malignancies ...
- 101
3
votes
2
answers
77
views
Is there any clinical evidence that PRP or MSC injections help spinal arthritis or disc problems?
I'm 40 years old, and remember the years in my youth when stem cells were touted as the great new miracle discovery. And like most promising new discoveries I've seen the press quietly died away and ...
- 131
1
vote
0
answers
24
views
Chronic Myeloid Leukemia blast percentage
I'm trying to understand the oncogenesis of CML. I have a question about CFC cells and blast cells. Are those the same? I know that in the chronic phase of CML there is a blast percentage of 1-10% of ...
- 11
1
vote
0
answers
45
views
Is the MSC-based regenerative medicine promising for Ischemic stroke stroke patients? ; two points difference in the 47-point test
Many papers says, regenerative medicine using MSCs are promising for Ischemic stroke stroke patients. But in my layman's sense, various data don't seem promising. So, I want to hear the opinions of ...
- 437
1
vote
1
answer
42
views
How can a potential patient grow tissues from their stem cells to have surgically implanted?
It is common knowledge that stem cells, including adult stem cells, can be used to create any other type of cell from the individual it comes from. There are many examples going back decades of stem ...
anon
3
votes
1
answer
220
views
The role of growth factors in haemopoiesis
I am currently studying the textbook Hoffbrand's Essential Haematology, eighth edition, by A. Victor Hoffbrand and David P. Steensma. Chapter 1 Haemopoiesis says the following:
SCF, TPO and FLT3 ...
- 197
1
vote
2
answers
116
views
Why are there no "ethically unobjectionable" alternatives to HEK-293, WI-38, MRC-5, etc?
The cell lines in the title all come from aborted fetuses. This presents an ethical quandary for those opposed to abortion. It seems straightforward to obtain new cell lines from sources other than ...
- 133
1
vote
0
answers
11
views
Transplant in combination with stem cell transplant
I was wondering, if you transplant a kidney from person A to person B and combine it with a stem cell transplant, would you then need no/less immunosuppressive drugs? Since you would have an antibody ...
- 21
2
votes
1
answer
126
views
What happens when a candidate drug becomes an ATMP？ What's the list of ATMPs?
According to The Alliance for Regenerative Medicine, the following six Tissue-Engineered Products are available in Europe.
Spherox
Novocart 3D
ReNovaCell
ReGenerCel
Vergenix FG
Vergenix-STR
I ...
- 437
3
votes
0
answers
72
views
Why has the Notch1 intracellular domain-transfected MSC expected as the greater regenerative medicine for ischemic stroke?
In Japan, SanBio's investigational regenerative medicine product, SB623, become a hot topic.
The 'active ingredient' of SB623 seems to be gene-modified mesenchymal stem/stromal cells. That cells ...
- 437
1
vote
1
answer
246
views
What’s keeping us from growing organs from stem cells?
If we know how to cause embryonic stem cells to differentiate into different tissue types, and we know how embryonic development turns those tissues into organs, why can’t we yet grow entire human ...
- 3,256
1
vote
1
answer
74
views
How can I preserve my stem cells?
I'm considering preserving (banking / cryopreserving) stem cells while young on in off-chance it becomes useful in the future.
I couldn't find any organizations providing this service. Is it because ...
- 59
2
votes
0
answers
51
views
Is it technically possible to replace aging body part and live forever? [closed]
I heard that iPS cells can be used to make some human organs (Takebe, et al. 2013).
If we make young organs using regenerative medical techniques and replace aging organs with them, can we live ...
- 121
1
vote
0
answers
21
views
What if we replace the DNA in stem cells with ours and we place the cells inside damaged organs to heal them?
I don't know a lot about stem cells or if a person's DNA could affect them in such a manner that if a person would have a damaged limb or organ, it would make it grow back with stem cell treatment.
- 11
4
votes
0
answers
84
views
Can fasting destroy our adaptive immune system?
Fasting for 72 hours been shown to lead to white blood cell regeneration (1). The cells basically die after several days, and are created again from stem cells upon feeding. This article describes how ...
- 171
3
votes
1
answer
91
views
Bone marrow donation vs. peripheral blood stem cell transplantation
There are two ways of donating to help patients with destroyed stem cells: one surgical (bone marrow donation) and one nonsurgical that is done with a process that is similar to donating blood (...
- 6,998
5
votes
0
answers
63
views
Is there any clinical evidence supporting or infirming the usefulness of stem cell therapy to treat a lateral epicondylopathy for humans?
I have read some claims about the usefulness of stem cell therapy to treat a lateral epicondylopathy.
Example (mirror):
Innovative treatments that include stem cell therapy, supplements, growth ...
