Questions tagged [stem-cells]
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Alternative to Limb Lengthening
Some of you who are familiar with the current surgery for limb lengthening know the steps (link):
Break bones
Insert rod
Await callus formation
Lengthen
Consolidate
The issue is during the ...
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Can we develop milder drugs to eliminate hematopoietic stem cells?
Eliminating preexisting hematopoietic stem cells (HSC) is a necessary step before HSC transplant. Traditionally this "adjuvant" treatment is performed by means of high dose chemotherapy and ...
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Is there any clinical evidence that PRP or MSC injections help spinal arthritis or disc problems?
I'm 40 years old, and remember the years in my youth when stem cells were touted as the great new miracle discovery. And like most promising new discoveries I've seen the press quietly died away and ...
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Chronic Myeloid Leukemia blast percentage
I'm trying to understand the oncogenesis of CML. I have a question about CFC cells and blast cells. Are those the same? I know that in the chronic phase of CML there is a blast percentage of 1-10% of ...
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Is the MSC-based regenerative medicine promising for Ischemic stroke stroke patients? ; two points difference in the 47-point test
Many papers says, regenerative medicine using MSCs are promising for Ischemic stroke stroke patients. But in my layman's sense, various data don't seem promising. So, I want to hear the opinions of ...
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How can a potential patient grow tissues from their stem cells to have surgically implanted?
It is common knowledge that stem cells, including adult stem cells, can be used to create any other type of cell from the individual it comes from. There are many examples going back decades of stem ...
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The role of growth factors in haemopoiesis
I am currently studying the textbook Hoffbrand's Essential Haematology, eighth edition, by A. Victor Hoffbrand and David P. Steensma. Chapter 1 Haemopoiesis says the following:
SCF, TPO and FLT3 ...
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Why are there no "ethically unobjectionable" alternatives to HEK-293, WI-38, MRC-5, etc?
The cell lines in the title all come from aborted fetuses. This presents an ethical quandary for those opposed to abortion. It seems straightforward to obtain new cell lines from sources other than ...
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Transplant in combination with stem cell transplant
I was wondering, if you transplant a kidney from person A to person B and combine it with a stem cell transplant, would you then need no/less immunosuppressive drugs? Since you would have an antibody ...
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What happens when a candidate drug becomes an ATMP？ What's the list of ATMPs?
According to The Alliance for Regenerative Medicine, the following six Tissue-Engineered Products are available in Europe.
Spherox
Novocart 3D
ReNovaCell
ReGenerCel
Vergenix FG
Vergenix-STR
I ...
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Why has the Notch1 intracellular domain-transfected MSC expected as the greater regenerative medicine for ischemic stroke?
In Japan, SanBio's investigational regenerative medicine product, SB623, become a hot topic.
The 'active ingredient' of SB623 seems to be gene-modified mesenchymal stem/stromal cells. That cells ...
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What’s keeping us from growing organs from stem cells?
If we know how to cause embryonic stem cells to differentiate into different tissue types, and we know how embryonic development turns those tissues into organs, why can’t we yet grow entire human ...
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How can I preserve my stem cells?
I'm considering preserving (banking / cryopreserving) stem cells while young on in off-chance it becomes useful in the future.
I couldn't find any organizations providing this service. Is it because ...
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Is it technically possible to replace aging body part and live forever? [closed]
I heard that iPS cells can be used to make some human organs (Takebe, et al. 2013).
If we make young organs using regenerative medical techniques and replace aging organs with them, can we live ...
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What if we replace the DNA in stem cells with ours and we place the cells inside damaged organs to heal them?
I don't know a lot about stem cells or if a person's DNA could affect them in such a manner that if a person would have a damaged limb or organ, it would make it grow back with stem cell treatment.
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Can fasting destroy our adaptive immune system?
Fasting for 72 hours been shown to lead to white blood cell regeneration (1). The cells basically die after several days, and are created again from stem cells upon feeding. This article describes how ...
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Bone marrow donation vs. peripheral blood stem cell transplantation
There are two ways of donating to help patients with destroyed stem cells: one surgical (bone marrow donation) and one nonsurgical that is done with a process that is similar to donating blood (...
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Is there any clinical evidence supporting or infirming the usefulness of stem cell therapy to treat a lateral epicondylopathy for humans?
I have read some claims about the usefulness of stem cell therapy to treat a lateral epicondylopathy.
Example (mirror):
Innovative treatments that include stem cell therapy, supplements, growth ...
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