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Questions tagged [transplant-rejection]

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Why does a bone marrow transplant recipient need to match their donor if their own immune system is going to be entirely replaced?

I am new here at Medical Science SE (first ever question!) and perhaps I sound like an idiot, but... Why (or how) would a bone marrow transplant recipient's native immune system attack the new bone ...
Kurt Hikes's user avatar
2 votes
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What is the mechanism of immune privilege that prevents immunological damage in some organs?

I was reading about immune privilege in a paper called Immune Privilege of Heart Valves by Hill et al. Immune privilege is summarised as follows: Immune privilege is an evolutionary adaptation that ...
Chris's user avatar
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4 votes
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What advances have been made in liver transplants in the past 30 years?

Imagine someone needing a liver transplant 30 years ago versus today. What advances have been made to make the procedure safer now? My research I know that the constant in all organ transplants has ...
Rohit Pandey's user avatar
3 votes
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Why are anti-rejection drugs necessary in organ transplant? [closed]

A key step of the organ transplant process is matching, where blood type, leukocyte antigens, crossmatch antibodies, etc. are checked to ensure compatibility. If these tests pass, and the organ is ...
Tal's user avatar
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Effects of Garlic on Tacrolimus via CYP3A4

Garlic is said to be an inducer of CYP3A4, Tacrolimus is metabolized by CYP3A4. The list of drugs (and some foods) interacting with Tacrolimus is long but nowhere I found a note on garlic. Grapefruit ...
Llarian's user avatar
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3 votes
1 answer

How can a bone marrow transplant from a donor of a different blood type not get rejected?

As discussed here, one can change their blood type by getting a bone marrow transplant from a donor with a different blood type. Why would the bone marrow not be rejected, as the body's immune ...
DonielF's user avatar
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2 votes
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What factors, beside blood-type, are considered a "good match" for organ transplants?

Matchmaker, matchmaker, make me a match; find me a find; catch me a catch! I know there are probably a whole litany of factors that are considered to match organ donors with those needing organs so ...
Pills N Pillows's user avatar