I’m a newbie and utterly unfamiliar with biomedicine, but I’ve been reading a few scientific articles recently and a question has been nagging me ever since.
So apparently preserving donor organs long enough for transplant is a huge challenge. If cryopreservation or ex vivo perfusion can, at best, prolong organ survival by a few hours/days, why not just put them into host animals such as pigs? Xenotransplantation has become really successful in recent years, with graft survival for over 100 days, so why can’t we just put the human donor organs inside genetically-engineered immunodeficient pigs to preserve their function?
I’ve read about this guy who did something similar: https://onlinelibrary.wiley.com/doi/full/10.1111/ajt.13149 But he was using fetal organs harvested from aborted fetuses, rather than adult donor organs.