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Towards safer chemotherapy: What is the current state of cancer therapy using targeted drug-delivery?

I work in the biophysics of making non-viral drug-delivery vectors, which can encapsulate the drug molecules and release the drugs at targeted sites. The release mechanism at targeted sites are ...
user35952's user avatar
  • 101
4 votes
1 answer
118 views

Can we develop milder drugs to eliminate hematopoietic stem cells?

Eliminating preexisting hematopoietic stem cells (HSC) is a necessary step before HSC transplant. Traditionally this "adjuvant" treatment is performed by means of high dose chemotherapy and ...
哲煜黄's user avatar
  • 143
0 votes
1 answer
30 views

Why aren't purine analogs effective in non-hematological malignancies?

FDA has approved many purine analogs e.g. thioguanine, cladribine, pentostatin, mercaptopurine for various forms of leukemia and/or lymphoma, but none for non-hematological malignancies. What makes ...
odnerpmocon's user avatar
1 vote
1 answer
33 views

How exactly does induced Scalp Hypothermia prevent alopecia (hair loss) during chemo therapy?

Recent studies 1 of women getting chemo for early-stage breast cancer have found that at least half of the women using one of these newer devices lost less than half of their hair. 2 Scalp ...
Bob Ortiz's user avatar
  • 1,059
2 votes
1 answer
44 views

What kind of cell kill probabilities per division you get with chemotherapy?

As I understand it, many chemotherapeutic drugs target cell division, with the theory that a constant kill probability per cell division kills fast-replicating cancer cells faster than slow-...
Sami Liedes's user avatar
2 votes
1 answer
55 views

Immune system recovery from chemotherapy

I'd like to know if your immune system will recover from chemotherapy, say, after x years, or will your immune system forever be weakened/compromised from chemotherapy?
Jason's user avatar
  • 21
7 votes
1 answer
146 views

Bleomycin and Oxygen

Do patients exposed to bleomycin as a part of their chemotherapy regime have to avoid exposure to concentrated levels of oxygen for the rest of their life? If not, how long after treatment ceases ...
Ron2781's user avatar
  • 101
3 votes
1 answer
633 views

Bleomycin and Cannabis

To my understanding, bleomycin has a considerably detrimental effect on the lungs of a patient taking it as a part of their chemotherapy regime. However, my question is, if a patient smokes cannabis (...
Ron2781's user avatar
  • 101
6 votes
2 answers
139 views

What are survival rates of male patients in stage IV throat cancer that has metastasised to the lower pallet?

The patient is receiving a combination of radiotherapy and chemotherapy. The surgery to remove the cancerous throat tissue was not entirely successful as the surgeon discovered that the cancer had ...
Sympa's user avatar
  • 779
3 votes
1 answer
158 views

Morning nausea after Chemo

I am 22, and my mom is 59. So, my mom got diagnosed with breast cancer back in 2005, and took radiation and chemotherapy in late 2005/2006. Anyway, she's doing well now except for red-green color ...
Chris Koro's user avatar