Yes, there is a big difference, it differs in our metabolism, the number of enzymes and the time of digestion. Why?
Let's break it down.
Stomach acid is a digestive fluid, formed in the stomach and is composed of hydrochloric acid (HCl) .05–0.1 M (roughly 5,000–10,000 parts per million or 0.5-1%)2 potassium chloride (KCl) and sodium chloride (NaCl).
The acid plays a key role in the digestion of proteins, by activating digestive enzymes, and making ingested proteins unravel so that digestive enzymes break down the long chains of amino acids.
Since we now know the meaning of stomach acid, let's categorize healthy foods and unhealthy foods. So by doing that let's give an example; fruits and vegetables are considered as healthy foods, right? and junk foods, noodles, and some processed foods are unhealthy.
So here's the thing, healthy foods like fruits and veggies contain enzymes that will help the process of digestion meaning, these enzymes plus the enzymes produced by our body can digest and break down these foods easily.
Whereas according to Mercola.com, the instant-noodle consumers
had a significantly lower intake of important nutrients like protein,
calcium, phosphorus, iron, potassium, vitamin A, niacin, and vitamin C
compared with non-consumers.7 Those who ate instant noodles also had
an excessive intake of energy, unhealthy fats, and sodium (just one
package may contain 2,700 milligrams of sodium).
Not to mention, refined carbohydrates like breakfast cereals, bagels,
waffles, pretzels, and most other processed foods quickly break down
to sugar in your body. This increases your insulin and leptin levels
and contributes to insulin resistance, which is the primary underlying
factor of nearly every chronic disease and a condition known to man,
including weight gain.
Not only that but remember… when you eat junk food you are not just
feeding yourself… you’re feeding your microbiome, too, and in so doing
altering its construction for better or worse. Your body’s diverse
army of microbes is responsible for many crucial biological processes,
from immunity to memory to mental health, so feeding it wisely, with
fresh unprocessed and naturally fermented foods is crucial to your
overall health and well-being.
"Research published in the Journal of Nutrition found that women who
consumed more instant noodles had a significantly greater risk of
metabolic syndrome than those who ate less, regardless of their
overall diet or exercise habits."
Study shows that processed foods are harder to digest than healthy foods like fruits and veggies.
By the way regarding with:
The endpoint is that I'm trying to find out will stomach acid combined
with healthy food make less damage to the esophagus
It is only possible if you have acid reflux.