Timeline for (Why) are there so few studies of ivermectin as an antiviral in animal models?
Current License: CC BY-SA 4.0
12 events
| when toggle format | what | by | license | comment | |
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| Jun 19, 2021 at 3:37 | answer | added | user1521620 | timeline score: -4 | |
| Feb 23, 2021 at 16:17 | answer | added | Blue Various | timeline score: 3 | |
| Feb 21, 2021 at 23:21 | comment | added | Blue Various | Is this what you mentioned "one animal trial"? This is not what covid19 is talking about. It would be too complicated to mention other viruses, so I would suggest limiting it to covid19 itself or the viruses which modeled after covid19 . | |
| Feb 21, 2021 at 22:48 | comment | added | Blue Various | I personally think that the results, including those in hamsters, are not clear-cut. It should also be noted that these papers are still in preprint. | |
| Feb 21, 2021 at 22:27 | comment | added | got trolled too much this week | @BlueVarious: interesting; one of those "found significant reductions in cytokine concentrations in the nasal turbinate’s and lungs of the treated animals despite the lack of apparent differences in viral titers". Which seem to indicate it wasn't perhaps working as an antiviral... but perhaps had some other effect similar to how some glucocorticoids help with Covid. | |
| Feb 21, 2021 at 22:18 | comment | added | Blue Various | The report seems to cite several studies in mouse and hamster models (see PP.5-6) covid19criticalcare.com/wp-content/uploads/2020/11/… | |
| Feb 19, 2021 at 14:39 | comment | added | Blue Various | Thanks for the reply. Thanks for the info on the animal studies regarding the vaccine. But I think it's unfair not to compare it with the same antiviral agents. There seem to be many different antiviral candidates, what about them? covid19treatmentguidelines.nih.gov/antiviral-therapy | |
| Feb 15, 2021 at 21:18 | comment | added | got trolled too much this week | @BlueVarious: Besides, the theory is that ivermectin is a broad spectrum anti-viral due to its mechanism of action (at least the one advanced by Jans & Wagstaff); the more direct mechanism envisaged by other don't seem to even have in vitro studies done. | |
| Feb 15, 2021 at 21:18 | comment | added | got trolled too much this week | @BlueVarious: there are plenty of animal models for Covid-19. And yeah Covid vaccines have been tested that way too. And continue to be. | |
| Feb 15, 2021 at 20:07 | comment | added | Blue Various | What is a reliable animal model for covid19? How is animal studies have been done on other covid19 therapeutic candiates? I don't think it's fair to not compare it to other covid19 treatment candidates. | |
| Feb 9, 2021 at 17:37 | history | edited | got trolled too much this week | CC BY-SA 4.0 |
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| Feb 9, 2021 at 17:23 | history | asked | got trolled too much this week | CC BY-SA 4.0 |