De Novo
  • Member for 3 years, 6 months
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How is "histologically invasive diameter" assessed in live patients?
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4 votes

These patients were staged on surgery. Typically whole tumor is excised with clear margins confirmed intraoperatively. Note the measurement is diameter of the primary tumor. Nodes and mets are ...

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How do the MOAs differ that ACE-Inhibitors might not work, but Calcium Channel Blockers (CCB) do work
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As @DoctorWhom says, there is a great deal of variability in the effectiveness of single agents for blood pressure control. There are some subgroups of patients who are more likely to respond or not ...

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What are some conditions that would cause severe exercise intolerance?
3 votes

If you're looking for a disease with childhood onset that requires exercise restriction, Long QT Syndrome (LQTS) may work, specifically LQT1. Here is a lay overview. For more detail, see this review. ...

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What is Clinical Decision Support (CDS)?
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3 votes

What is Clinical Decision Support? This ends up getting a little bogged down in compliance mumbo jumbo, but Clinical Decision Support is defined by the US centers for medicare and medicaid services as:...

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Is rabies virus infectious outside host?
3 votes

Can rabies virus remain infectious on environment i.e on soil, grasses, leaves and water? Generally, an exposure requires a bite from an infected animal, or saliva or neural tissue to be introduced ...

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Can a medical doctor write a prescription which has not gone through a formal diagnosis to identify as needed?
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2 votes

Writing a script for someone so you can "get physical" with them is, of course, an ethical problem. As far as prescribing off the cuff for family and close friends, that depends. It may be quite ...

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What causes a notch in the atrial pressure?
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2 votes

The left atrial pressure tracing here is not the best part of this figure. It might have some pedagogical value if it were discussed in the text, but it's not. Measuring left atrial pressure ...

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How to avoid the diuretic effect of caffeine or green tea?
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Caffeine intake is associated with increased urination, but controlled studies (e.g., here and here) demonstrate fairly rapid adaptation and no chronic diuretic effect. For most people, if you want ...

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