9
votes
What determines whether an influenza virus causes the flu or a cold?
Is Influenza the disease simply a shorthand for a disease caused by an
Influenza virus that happens to clinically present as worse than a
cold?
Pretty much. You have to bear in mind that until the ...
4
votes
Why should the hepatitis B infection last more than six months to be regarded as chronic?
Acute infections of Hepatitis B viruses (actually other types too) tend to be duration limited to 4-8 weeks, though it can last as long as 6 months post-infection in rare cases (1). Chronic infection ...
1
vote
Why the FDA-approved drug label for sofosbuvir mentions "Without cirrhosis or with compensated cirrhosis" as indication?
TL;DR: No, decompensated cirrhosis is not a contraindication.
However, the safety and efficacy of Sovaldi have not been established in patients with decompensated cirrhosis:
Hepatic Impairment
No ...
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