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A few types of reactions can take place that cause the degradation of mRNA, including the oxidation of the RNA molecules with water and certain metals. However, "the main degradative event is the spontaneous cleavage of the phosphodiester linkage through transesterification resulting from a nucleophilic attack of the phosphorus atom by the neighboring 2′...


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It does make sense for some women and men to get the HPV vaccination at age 27 through 45 years. In June 2019, the Advisory Committee on Immunization Practices (ACIP), which advises the CDC about vaccinations, made recommendations about HPV vaccinations that included recommendations about “catch-up vaccination” in adults up to age 26 years along with a ...


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It appears that the UK is actually planning a challenge trial. This is rather interesting from an ethical point of view. https://www.theguardian.com/world/2020/sep/24/uk-covid-19-vaccine-trial-set-to-infect-healthy-volunteers-with-virus


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