62 votes
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Why will there be vaccines first before a cure for COVID-19?

Your question contains a lot of misconceptions. A cure is definitely possible A cure could be found, proved, and proved safe, more quickly than a vaccine People and firms that could be working on ...
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61 votes
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Do vaccines cause autism?

This has been a controversial dispute for a long time and it can involve a lot of personal opinion, but I will try to answer this as scientifically as possible. There hasn't been any viable evidence ...
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61 votes
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Is it advisable for a healthy male in his early 40s to take the influenza vaccine?

In general, the benefit of flu shots is to the general population. Taking the cited value of 40%-60% from the CDC, we can say that it might be a coin toss for you personally to be protected from ...
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48 votes
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Is SM-102 a safe ingredient in the Moderna vaccine, despite these safety warnings?

The MSDS linked to is for a product sold as a solution of 10% SM-102 in 90% chloroform. It's listed as "SM-102" because that's the interesting/useful thing that the company is selling. It's ...
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46 votes
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Are Covid-19 vaccines much more deadly than people (and scientists) think?

https://vaers.hhs.gov/data/dataguide.html provides a useful guide for interpreting these data. VAERS deaths are not causal reports, they're just a report where someone (doctor, family member) decided ...
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41 votes

Is it advisable for a healthy male in his early 40s to take the influenza vaccine?

Tackling your points in turn, in inverted order: flu is an irritant but nowhere near deadly You are probably confusing the flu (influenza) with the common cold, which is colloquially often called “...
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36 votes
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Why is the rate of circulating vaccine-derived poliovirus disease booming?

The short version is that in 2016 the polio vaccine changed. A more thorough explanation requires some background on the immunology of polio and its vaccines, which is not straightforward. Polio virus ...
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  • 476
33 votes

Father gets chickenpox, but doesn't infect his two children. How is this possible?

If there was close contact, if the 90% rate is accurate, and if occurrence is independent in related individuals, then you would expect 0.10 * 0.10 = 1% of contacts with 2 potentially vulnerable ...
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29 votes

Do vaccines cause autism?

You have already gotten an excellent answer on the scientific evidence for the autism-vaccination link (namely, that there isn't one). I would however like to address this part of your question ...
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  • 2,423
23 votes

Why will there be vaccines first before a cure for COVID-19?

Drugs are typically small molecules that interfere with some chemical process in the disease causing microbe, and therein lies the rub. Bacteria, fungi, protozoa, worms, etc. are sustained by their ...
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21 votes
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Why hasn't Russia's daily COVID-19 cases decreased as a result of its vaccine?

The initial Russian announcement was bluster. From the NYT's vaccine tracker: On Aug. 11, President Vladimir V. Putin announced that a Russian health care regulator had approved the vaccine, renamed ...
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19 votes
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A cheap and easy inactivated vaccine for COVID-19

The only approved inhaled vaccine is the flu vaccine delivered intra-nasally. It uses a live attenuated virus. There are a whole list of people who should not receive it because it's a live virus, ...
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17 votes

Is it advisable for a healthy male in his early 40s to take the influenza vaccine?

Influenza deaths are not specifically tracked in those over the age of 18 but they can be estimated from death certificates. CDC estimates that from 2010-2011 to 2013-2014, influenza-associated ...
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17 votes

How many people end up needing medical attention during the 15 minute window after receiving the Pfizer vaccine?

The most noteworthy complication, and most heard about in the news, is anaphylaxis. This article breaks down cases of anaphylaxis nicely: Reports of Anaphylaxis After Receipt of mRNA COVID-19 Vaccines ...
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  • 1,436
15 votes

Is it known how often unvaccinated children are contagious with symptom free diseases?

Unvaccinated members of a population contribute to the susceptibility of the rest of the population to disease, especially vulnerable people who cannot be vaccinated. This fact is true whether or not ...
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14 votes
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Why didn't smallpox develop resistance to its vaccine?

To answer this question, first it might be useful to talk about how a vaccine actually works: basically, through introducing dead or relatively harmless (attenuated) versions of a virus or bacteria (...
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14 votes

How cautious do I need to be with unvaccinated students around newborns?

There seems to be a link (as one would expect) between areas with a higher concentration of unvaccinated individuals and disease outbreaks (see this article and the source data map). The recent (2015)...
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14 votes

Is it advisable for a healthy male in his early 40s to take the influenza vaccine?

Influenza vaccines do not have satisfactory effective rates of preventing flu. Flu vaccination reduces the risk of flu illness by between 40% and 60% Vaccines aren't meant to stop diseases by making ...
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14 votes
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Father gets chickenpox, but doesn't infect his two children. How is this possible?

To add to @BryanKrause's answer re: rare events happen all the time, the children are not out of the woods yet. The mean incubation time for a primary VZV infection (the clinical syndrome known as ...
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  • 3,153
13 votes

How can a school be getting an epidemic of whooping cough if most of the students are vaccinated?

Per the CDC: A: Pertussis vaccines are effective, but not perfect. They typically offer good levels of protection within the first 2 years after getting the vaccine, but then protection ...
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13 votes

How many people end up needing medical attention during the 15 minute window after receiving the Pfizer vaccine?

The data on this aren't hard to find. Here are some more examples that specifically provide time frames to back up @A Rogue Ant's answer: For the Pfizer vaccine: During December 14–23, 2020, ...
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12 votes

Do vaccines cause autism?

Perhaps the question should be asked, can vaccines prevent autism? One fact of note is that postnatal infections with the vaccine-targeted infectious agents, including measles, mumps, and rubella, ...
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12 votes

Is it advisable for a healthy male in his early 40s to take the influenza vaccine?

Other answers have explained why being vaccinated is generally a good idea, and I fully support the ones that do. That said, the article you've linked to does indeed present some very scary points, ...
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12 votes

Why hasn't Russia's daily COVID-19 cases decreased as a result of its vaccine?

Answering my own question since I believe I've found the answer. According to this source, The senior minister at the department, Mikhail Murashko, announced last week that a nationwide mass ...
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11 votes

How cautious do I need to be with unvaccinated students around newborns?

If you are immunized, there is of course less risk of you contracting a given disease through contagion from an of an unvaccinated carrier. However, if your child is young enough (e.g. < 6 months ...
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10 votes

BNT162b2 mRNA Covid-19 Vaccine efficacy after 1st dose - explain the statistics

The paper itself describes how this is calculated (see the Methods section), but also see this Q&A at Biology.SE talking more broadly about how efficacy has been defined in these vaccine trials: ...
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9 votes
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Medical relevance of tetanus vaccination

Clostridium tetani is the causative organism in tetanus. It requires an anaerobic environment to grow so is found in soil and in the gut of animals. Person to person transmission is not possible. ...
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9 votes
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Delayed vaccination: effect on the immune system

The human immune system Basically, the human (and that includes all ages) immune system has two parts: The innate immune system is a very old part (which doesn't mean it's bad or superfluous, on the ...
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9 votes
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Can the HPV vaccine be effective if you are already infected?

The HPV vaccine is most effective when preventing you from initial infection. While common, it's possible you haven't been infected with HPV. Even if you are, there is some benefit to still being ...
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