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By "natural protein intake" they are referring to normal dietary protein intake, in contrast to amino acid supplements given as protein substitutes for people with disorders related to protein/amino acid metabolism. See for example from Wikipedia: Supplementary "protein substitute" formulas are typically prescribed for people PKU (...


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So, as far as I am aware there is no specific grading of severity of fracture. Severity in fractures can be individual and based on age, debility, etc. Most classification systems I am aware of are based on describing the fracture. Open/closed, oblique, longitudinal, etc. There are also specific common fractures with names, such as a tri-malleolar fracture ...


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The drug development process has several stages and before proceeding to human trials, parameters such as relative safety and probable therapeutic action are evaluated in order to assure safety and effectiveness on the treatment. Some information about the pharmacokinetics of a compound is also required before clinical evaluation is begun. - Katzung and ...


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