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We don't have any controlled trials but the physicians of the time greatly doubted the efficacy of mercury salves and inhalation LW Harrison, a medical officer in the Royal Army Medical Corps during World War I, described the effectiveness of Salvarsan and Neosalvarsan on soldiers who contracted syphilis during the war. [18]  Arsenic however, while being ...

You're asking about the false positive rates of syphilis blood tests in primary syphilis. It's a biostatistics thing. The AAFP has a good article on the "clinical dilemmas of syphilis." The VDRL and RPR, respectively, are reactive in 78 percent and 86 percent of patients with primary syphilis. They become positive within approximately four to six weeks ...

Yes, it is true that Zika can be transmitted sexually (from the CDC). However, Zika is generally classified as a mosquito-borne disease, not an STD, as mosquitoes are by far the most common vector of passage. I am not aware of transmission of "typical" STDs by mosquitoes, most likely because, as you say, the amounts of pathogenic material are extremely small,...

Syphilis is transmitted from person to person by direct contact with a syphilitic sore, known as a chancre. Chancres can occur on or around the external genitals, in the vagina, around the anus , or in the rectum, or in or around the mouth. Transmission of syphilis can occur during vaginal, anal, or oral sex. See more here: https://www.cdc.gov/std/syphilis/...