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Corticosteroids block the enzyme Phospholipase A2 (PLA2) which catalyses the first step in arachidonic acid synthesis pathway. But, NSAIDs blocks activity of cyclooxygenases (COX 1 and COX 2). So, by blocking this pathway at first step completely prevents the formation of of Arachidonic acid, but when this pathway is blocked later at step performed by COX ...


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