7

The short answer is maybe, but rarely, and the whole Covid virus has never been seen to integrate into the cell's DNA intact. Any integration requires "helper" molecules not found in the Covid virus, and only very rarely found in a normal cell. It's been known for many decades that RNA in a cell can be converted into DNA and integrated into the ...


7

This is probably as good as it gets for now, but experts quoted by AP have dismissed the idea as highly improbable, basically on the argument that the common sequence is too short to be of concern and that other viral fusion proteins e.g. used in the flu vaccine haven't been observed to cause such an effect (on fertility): Experts say there is no evidence ...


3

It's unclear to me what tissue you expect to be sampled. SARS-CoV-2 is a respiratory virus and like similar viruses it's (differentially) diagnosed by "nasal" (more accurately: nasopharyngeal) swabs and PCR or at most by doing the same (PCR) on the more invasive (to obtain) BAL samples, which are more commonly used in pneumonia cases. (The latter ...


3

Even assuming the same ecological conditions, efficacy of a vaccine is in a (dose-dependent trade-off with side effects. (This was e.g. easily shown in the phase I/II trials of Moderna's vaccine.) Even for the exact same tech/vaccine, manufacturers may choose different points along this curve. Furthermore, the amount of "training" and thus ...


2

The India-produced Covishield vaccine and the AstraZeneca COVID-19 Vaccine (codenamed AZD1222) are intended to be identical. Covishield is manufactured by Serum Institute of India under license from AstraZeneca, in the same manner as manufacturing of AZD1222 has been licensed to companies in Thailand and South Korea.1 The agreements include transfer of the ...


1

Well, it's hard for me to say how closely this matches the Chinese testing methods, but there is one study from Nigeria that compared the methods: Diagnosis of coronavirus disease 2019 (COVID-19) is currently established with a polymerase chain reaction (PCR) test by means of oropharyngeal-, nasopharyngeal-, anal-swabs, sputum and blood plasma. However, ...


1

The Rhea et al. article on SARS-CoV-2 suggests that the S1 protein crosses the BBB by a specific mechanism (general albumin protein does not cross at the same time), so no general disruption of the BBB is indicated (See Fig. 1 in paper). The authors also note "Based on experiments with the glycoprotein WGA, we found that brain entry of I-S1 likely ...


1

This fact sheet on the Elecsys Anti-SARS-CoV-2 S test from Roche, the test manufacturer, has useful information. In particular it notes: You should not interpret the results of this test as an indication or degree of immunity or protection from infection.


1

From Wikipedia: The spikes are the most distinguishing feature of coronaviruses and are responsible for the corona- or halo-like surface. On average a coronavirus particle has 74 surface spikes.[54] Each spike is about 20 nm long and is composed of a trimer of the S protein. The S protein is in turn composed of an S1 and S2 subunit. So, a spike protein in ...


1

Dry heat sterilization is fairly inefficient, time-wise, in general. According to Wikipedia, which cites the CDC for this: The proper time and temperature for dry heat sterilization is 160 °C (320 °F) for 2 hours or 170 °C (340 °F) for 1 hour or in the case of High Velocity Hot Air sterilisers 190°C (375°F) for 6 to 12 minutes. But this is for all mirco-...


Only top voted, non community-wiki answers of a minimum length are eligible