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To add to Chris' answer, if you consider heart attack and sudden cardiac arrest to be negative health effects, then the answer is almost any dose at any frequency. Cocaine is a powerful vasoconstrictor and also a powerful stimulant that raises your blood pressure and heart rate. So if you happen to have, say, an asymptomatic partial blockage of one of your ...


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Cocaine is highly addictive and an astonishing waste of money. You also come across as attempting to normalize or explain what is probably already an addiction. I have heard the same lines from dozens of people experimenting with addictive drugs. The main danger is cutting agents as these can include glass, crushed caffeine pills, pain-killers, amphetamines ...


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