6 votes
Accepted

Could a nerve agent be used recreationally?

Okay, this is the closest you're going to get to a "military grade" nerve agent that elevates your mood: using botox as an antidepressant. Botulinum toxin A (botox) is a nerve agent. In fact, it's ...
faustus's user avatar
  • 785
6 votes

Could a nerve agent be used recreationally?

"Recreational drugs" have "psychotropic effects," which means they affect the mood and perception of stimuli in the brain. Both alcohol and heroin are psychotropic drugs. Alcohol acts mainly on the ...
Jan's user avatar
  • 15.9k
5 votes
Accepted

Is there an interaction between methamphetamine and dental anesthetic?

Catecholamines This interaction relates to a broad family of hormones called catecholamines. There are many examples and they share a common structure. Dopamine Adrenaline (epinephrine) Notice the ...
Chris's user avatar
  • 3,332
5 votes
Accepted

Appearance of heroin addicts

What in the world is going on? Are they injecting themselves in the middle of their cheek or forehead? That sounds unlikely. Or what would be an explanation... Perhaps a disease of some kind, not the ...
faustus's user avatar
  • 785
5 votes
Accepted

How does a blind person react to hallucinogenic drugs

I guess the best way would be to convince a blind person to take some psilocybin mushrooms or LSD. Perhaps they would actually see some fractals and stuff, since those visions are generated in the ...
user2361's user avatar
  • 236
5 votes

Is amyl nitrite used for sex?

Amyl Nitrite Treats and prevents chest pain (angina pectoris). And more pertinent for the question: On the street, this medicine and others like it are sometimes called "poppers." They have ...
Pobrecita's user avatar
  • 2,965
4 votes

What are the risks LSD microdosing?

Here are the sources you can use: The main issue is that due to government controls on substances like LSD, very little research ends up being conducted with/about them due to the difficulties and ...
Alexander Eichner's user avatar
4 votes
Accepted

Do the derivatives of cannabis have the same effect on the brain?

Hemp has a highly heterogenous chemical composition. ∆9Tetrahydrocannabinol (THC) is just one of many active substances. Although THC is the most psychotropic 'ingredient' in cannabis it is by far not ...
LаngLаngС's user avatar
  • 6,897
4 votes
Accepted

Why some people experience no side effects from a drug?

Most drugs have wanted (main) and unwanted (side) effects, but neither of them are guaranteed. For example, aspirin may or may not relieve your headache and may or may not upset your stomach. The ...
Jan's user avatar
  • 15.9k
4 votes

What is the cause of the vaping-related outbreak of lung injuries?

There are some data about possible causes of vaping-related lung damage, the type of the damage and symptoms, but not about the changes in medical history questionnaires, vaping habits or e-cigarette ...
Jan's user avatar
  • 15.9k
4 votes

Quantify third-hand smoke exposure risk

The following are studies which indicate cancer risks from third hand tobacco smoke which to me seems non-ambiguous. Sleiman, M., Logue, J. M., Luo, W., Pankow, J. F., Gundel, L. A., & ...
Chris Rogers's user avatar
  • 6,185
3 votes

Are there tables that compare deadly effects of various psychoactive drugs?

These tables you wish for are not quite exactly in the format you would seem to like them and as far as I know not available for a "global every substance we know" analysis. It is also quite difficult ...
LаngLаngС's user avatar
  • 6,897
3 votes

Early signs of cocaine addiction

Some signs of addiction are enlarged pupils, increased alertness and energy, loss of interest in food and sleep, increased talkativeness, rapid mood changes, increased heart rate, nasal congestion. ...
Elmer Hoffman's user avatar
3 votes

Could drug abuse possibly make eyes smaller?

Yes What you are taking is somewhat 25-times the recommended amount for medication. You are probably experiencing a fairly strong addiction to the drug. Yes, addiction can do many things to your body,...
Narusan's user avatar
  • 6,891
3 votes

Is ethanol toxic to liver, in the absence of ethanol metabolites resulting from inhibiting alcohol dehydrogenase(ADH) enzyme?

Seems like you answered your own question. Lowering the threshold for intoxication lowers the threshold for toxicity. The likelihood of acute ethanol poisoning is increased by coadministering these ...
Brian Ó Maoláin's user avatar
2 votes

Could a nerve agent be used recreationally?

Contra to Jan's answer, "so they do not have psychotropic effects"... actually they do. First, acetylcholine is a CNS neurotransmitter as well. Second, nerve agents aren't that selective (like many ...
the gods from engineering's user avatar
2 votes
Accepted

What is the cause of the vaping-related outbreak of lung injuries?

While it could still be a mixture of acute reasons: metals, dust, plainly unknown toxins; the underlying reason seems not to be that plant matter is vaped, nor that liquids are vaped. It also seems ...
LаngLаngС's user avatar
  • 6,897
2 votes

When does cocaine begin to induce negative health effects?

To add to Chris' answer, if you consider heart attack and sudden cardiac arrest to be negative health effects, then the answer is almost any dose at any frequency. Cocaine is a powerful ...
Carey Gregory's user avatar
  • 9,862
2 votes

When does cocaine begin to induce negative health effects?

Cocaine is highly addictive and an astonishing waste of money. You also come across as attempting to normalize or explain what is probably already an addiction. I have heard the same lines from dozens ...
Chris's user avatar
  • 121
2 votes
Accepted

Is non-smoked nicotine a smoking cessation-aid?

Yes, nicotine replacement therapy is used in multiple forms, including a skin patch and oral dosing with gums and lozenges. The purpose is to help avoid the side effects of nicotine withdrawal, while ...
Bryan Krause's user avatar
  • 14.1k
2 votes

Why some people experience no side effects from a drug?

One of the major things about heroin is that it is metabolized by the body as morphine and, if this person in the throes of heroin withdrawal were given medication like methadone, it couldn't be done ...
Angelfirenze's user avatar
2 votes

How does a blind person react to hallucinogenic drugs

There are TONS of trip reports on various sites—namely Reddit, Erowid, and DMT-Nexus. And while much of this is anecdotal evidence, one could do a lit review of these as a first step toward a more ...
Shannon Scott Schupbach's user avatar
2 votes

What are the risks LSD microdosing?

The 2022-02-10 study {1} didn't find any risks for LSD microdosing: We conclude that within the context of a controlled setting and a limited number of administrations, repeated low doses of LSD are ...
Franck Dernoncourt's user avatar
1 vote

Why is it that psychoactive drugs tend to be dangerous?

the illicit drug supply chain has an incentive to make drugs addictive but safe, as a dead client is a bad client Theoretically yes, however, safety is a cost factor. Everything from packaging to ...
life-on-mars's user avatar
1 vote

Why is it that psychoactive drugs tend to be dangerous?

Question: Why is it that psychoactive ("feel good") drugs tend to be dangerous? The question implies that psychoactive drugs are 1) dangerous and that 2) the reason is in their low therapeutic ...
Jan's user avatar
  • 15.9k
1 vote

Drug abuse and hair loss

Some amphetamines can cause hair loss. The mechanism how this happens does not appear to be known. Also some anabolic steroids (AAS) can cause it, presumably through conversion to DHT. The situation ...
the gods from engineering's user avatar
1 vote

What are the side effects of habitual cocaine usage, particularly the visually noticeable ones?

Cocaine is a highly addictive substance. What starts off as seemingly harmless experimentation can quickly develop into a potentially life-threatening addiction with devastating personal, professional,...
Chris Pentecost's user avatar

Only top scored, non community-wiki answers of a minimum length are eligible