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The Rhea et al. article on SARS-CoV-2 suggests that the S1 protein crosses the BBB by a specific mechanism (general albumin protein does not cross at the same time), so no general disruption of the BBB is indicated (See Fig. 1 in paper). The authors also note "Based on experiments with the glycoprotein WGA, we found that brain entry of I-S1 likely ...


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