Nociceptor sensitization and ACh release
Short answer Excessive Acetylcholine (Ach) release seems to be related Calcitonin Gene-Related Peptide (CGRP) inducing Ach leakage. CGRP is part of a general inflammatory response, in turn part of the ...
Sensitization and Ischaemia
Increased vascular permeability means fluid leaks more readily from blood vessels. That leakage builds up in the surrounding tissue, which causes edema. The edema squeezes veins, thereby compressing ...
Sensitization and Energy Crisis in Myofascial Pain Syndrome
A chain of events that leads to release of sensitizing substances, according to Dry needling — peripheral and central considerations (PubMed Central, 2011): ...muscle pain would cause spasm of ...
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