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4 votes

Nociceptor sensitization and ACh release

Short answer Excessive Acetylcholine (Ach) release seems to be related Calcitonin Gene-Related Peptide (CGRP) inducing Ach leakage. CGRP is part of a general inflammatory response, in turn part of the ...
AliceD's user avatar
  • 393
2 votes

Sensitization and Ischaemia

Increased vascular permeability means fluid leaks more readily from blood vessels. That leakage builds up in the surrounding tissue, which causes edema. The edema squeezes veins, thereby compressing ...
Carey Gregory's user avatar
  • 9,946
1 vote

Sensitization and Energy Crisis in Myofascial Pain Syndrome

A chain of events that leads to release of sensitizing substances, according to Dry needling — peripheral and central considerations (PubMed Central, 2011): ...muscle pain would cause spasm of ...
Jan's user avatar
  • 15.9k

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