5 votes
Accepted

Dr. prescribed Ondansetron/Zofran for migraines & says it'll help with weight loss too. How effective is it for either (migraines/weight loss)?

Your question contains two parts. So I will address them separately. First here a small background on ondansetron: Ondansetron is a selective antagonist at 5-HT3 receptors. It is most frequently used ...
M. Arrowsmith's user avatar
5 votes
Accepted

Migraines and tryptophan

Sumatriptan activates vascular 5-HT1 receptors. This results in vasoconstriction, which is what is thought to help the migraines. This is the same idea for giving caffeine, which is also a ...
Thomas TJ Checkley's user avatar
4 votes
Accepted

Can lumbar/sacral/thoracic spinal injury cause migraines?

The headache after lumbar puncture is common (~30%) and is not migraine headache. The mechanism is not entirely clear but likely involves a drop of cerebrospinal fluid volume and/or pressure (PubMed): ...
Jan's user avatar
  • 15.9k
4 votes

Can a headache be caused solely by a smell?

Certainly, headaches can be caused by a variety of smells, perfumes, paints, gasoline, bleach and yes, air fresheners. A study in 200 migraine patients showed perfumes were the first most common ...
Scientificpr's user avatar
3 votes

Do painkillers cure headaches or just stop us from feeling it?

Are painkillers curative for migraine headaches? No, they are not, but they are therapeutic. Similarly to user @De Novo's comment, the main problem in migraine headaches is the pain. Although the ...
nash's user avatar
  • 61
3 votes

Why is there no triptan on the WHO's list of essential medicine?

The following is from the 2007 WHO Expert Committee meeting regarding the addition of sumitriptan: The Committee noted that the application was generally of poor quality and provided only a ...
faustus's user avatar
  • 785
3 votes

Are botox injections approved by the FDA to treat chronic migrraines?

BOTOX is a prescription medicine that is injected into muscles and used to prevent (not treat) headaches in adults with chronic migraine who have 15 or more days each month with headache lasting 4 or ...
Pramanik MDMC's user avatar
2 votes

Why are chocolate and cheeses common triggers for migraines?

There are numerous papers on foods that appear to induce headaches. One recent paper (part 1) is Martin & Vij (2016). It goes into detail into the major players in foods that induce headaches. ...
Thomas TJ Checkley's user avatar
2 votes

Do painkillers cure headaches or just stop us from feeling it?

How do painkillers work? When part of your body is injured, special nerve endings send pain messages back to your brain. Painkilling drugs interfere with these messages, either at the site of the ...
Krishna Mohan's user avatar

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