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8 votes
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Are all kinds of liquor and alcohol equally bad for liver?

The only difference it makes to the liver how alcohol is consumed is how high the blood alcohol content becomes and for how long - the other particulars of the beverage will be filtered out by the ...
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7 votes

Can toxins accumulate in the liver?

Detoxification is one of the primary functions of the liver. When you ingest something, if it is absorbed, it enters the portal vein which delivers the blood directly to the liver. There, the liver ...
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7 votes

I have natural immunity to Hepatitis B. Do I pose risk to others?

The Hepatitis B core antibody test is positive for IgG but negative for IgM indicating that you had the hepatitis B infection a while ago. The negative hepatitis B surface antigen test means that they ...
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  • 13.2k
6 votes

Can superficial injury and exercise elevate AST and LDH levels?

Right now I can address the question on intensity, it seems that pushing things a bit too hard at the gym can cause elevated levels to trigger a detectable increase in AST and LDH, this is also ...
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  • 61
5 votes

How does alcoholism technically (chemically) kill you?

On the chemical level, the toxicity of ethanol is mainly mediated by its breakdown product acetaldehyde. Alcohol is metabolized like this: ethanol → acetaldehyde → acetate &...
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  • 15.6k
4 votes

Effects of microdosing alcohol on liver performance and the ability to metabolize toxins

What are effects of microdosing alcohol on the liver's ability to metabolize toxins? There seems to be no effect. Alcohol can induce the enzyme system CYP2E1 in the liver, which can speed up the ...
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  • 15.6k
4 votes

Tattoo on person with hepatitis b

A tattoo will be irrelevant to the person with Hep-B receiving it. The risks will be the same as anyone else receiving a tattoo, except of course that Hep-B won't be among those risks as it normally ...
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  • 9,345
4 votes
Accepted

What causes elevated liver function tests in a young asymptomatic patient?

Two important questions: Has AST/ALT elevation been present only once in blood sample? Is the elevation more than 3x the upper limit? Basis for "normal" values should be understood. "Normal" values ...
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  • 2,322
4 votes
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Do compounds absorbed through the skin bypass the liver?

It seems that your friend has confused first-pass metabolism with overall liver metabolism. Anything that goes into your digestive tract (including the medicines taken (per)orally) goes straight to ...
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  • 2,823
3 votes

What are the likeliest causes for rising indirect bilirubin levels?

It is impossible to make a definite diagnosis based solely on the given data. But there are some likely options which should all be checked. Here are the possibilities and test which should be done to ...
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3 votes

Is ethanol toxic to liver, in the absence of ethanol metabolites resulting from inhibiting alcohol dehydrogenase(ADH) enzyme?

Seems like you answered your own question. Lowering the threshold for intoxication lowers the threshold for toxicity. The likelihood of acute ethanol poisoning is increased by coadministering these ...
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3 votes

Does the liver produce less cholesterol if a person eats a lot of cholesterol?

"The net daily synthesis of cholesterol is equal to the amount of cholesterol lost in the feces minus the dietary cholesterol" The body synthesizes an amount approximately equal to the amount it ...
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  • 828
3 votes

Can acute liver failure be caused by an alcohol binge?

Can acute liver failure be caused by an alcohol binge? Yes Are the harmful effects of alcohol on the liver limited to chronic abuse? No. The harmful effects of alcohol on the liver are ...
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  • 6,747
3 votes

Can toxins accumulate in the liver?

No, these claims do not hold any validity. As you have said, the claims are vague, often saying that these "toxins" (not specified) are the cause of a catch-all list of symptoms. Unsurprisingly, they ...
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2 votes

Why is treating hepatic vein injuries so difficult?

The part of the question about passive euthanasia is an ethical question, which in my opinion does not fit for Health.SE. From INJURY SEVERITY SCORING: a Hepatic avulsion, which is given with ...
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  • 354
2 votes

Is it safer to take Naproxen once a day or twice a day?

Naproxen has a half-life of between twelve and seventeen hours.1 Constant steady-state serum levels of Naproxen are produced after four to five days..1 It stands to reason that the lower the dose the ...
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  • 1,390
2 votes

Quick way to determine if a medication is processed in the kidneys or liver?

drugs.com is a great resource. Go to the a Pro Edition header. Once you pull up the medication, scroll down until you find the Pharmacology Category. Once here, look for Metabolism and Elimination. ...
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  • 107
2 votes

What does it mean for a medication to be "hard for the liver" or "hard on the kidneys"?

"Hard on the liver or kidneys" means that the medication is making this organ work harder, damaging it or so potent that the medication is harder to rid from the body. Thinking about the liver: ...
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  • 2,952
2 votes

Pancreatitis and consumption of alcohol

In general, if the episode of acute pancreatitis was not due to alcohol consumption and has completely resolved, it would be relatively safe for an individual to resume limited alcohol consumption. ...
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2 votes

Why liver damage from Isoniazid (medicine of TB) is more in Africans? What is it that make Caucasians more immune?

Firstly the causes of liver failure in those taking the drug (1): The cause of liver injury due to Isoniazid is believed to be accumulation of a toxic intermediate of its metabolism. Rates of injury ...
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2 votes
Accepted

Does some ingredient in coffee actually help the liver break down fibrosis?

The conclusion of the mentioned systematic review with meta‐analysis: coffee consumption and the risk of cirrhosis (Alimentary Pharmacology & Therapeutics, 2016): This meta‐analysis suggests ...
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  • 15.6k
2 votes
Accepted

Can the liver not recover from cirrhosis caused by alcohol related damage?

At present time, hepatic cirrhosis is still an irreversible end stage chronic disease (Johnson and Sherding, 2006). In a nutshell its featured by successive cycles of injury/repair and inflammation ...
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  • 473
2 votes
Accepted

Could a living donor donate their liver multiple times in their lifetime?

Liver donation - an act of great honor - should only be done once. Liver regeneration occurs via compensatory hyperplasia. Regeneration of the liver can be more correctly defined as compensatory ...
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  • 362
2 votes
Accepted

How long after drinking alcohol is it safe to eat durian again?

This inability to mix durian with alcohol has the status of a food myth. To quote the dietetic department at Changi Hospital Eating durian and drinking beer at the same time may kill you There is no ...
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  • 13.2k
1 vote

How many people are affected by hepatocellular carcinoma (HCC) worldwide today?

1) Global incidence for HCC, 2018: What is the global incidence of hepatocellular carcinoma (HCC) worldwide? (Medscape, 2019): Worldwide, liver cancer was the fifth most common cancer and the ...
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  • 15.6k
1 vote

How many calories does it burn to regrow a liver?

To get the answers started, though admittedly with a very rough estimation, I'll add my own idea of a lower bound of calories burned to regrow an entire liver. Because basic laws of thermodynamics ...
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1 vote

Do compounds absorbed through the skin bypass the liver?

No. We'll go through two examples of why not. Dermal application of medicine. If the main goal of this is to get the medicine circulating in your blood for systemic applications, and the drug is ...
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  • 41
1 vote
Accepted

Sleeping position with Hepatitis A

I might hazard a guess that "don't put pressure on your liver" means don't take medications that might tax the liver, or drink alcohol, etc. I don't think they meant "don't squeeze the liver." ...
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