13
votes
Does an organ of a male donor work on a female patient?
The Chromosomes are not the main Factor in this. The immune system (and antibodies) is, this is a bit different. For example females have a higher HLA antigens and therefore rely on more ...
- 381
6
votes
Does an organ of a male donor work on a female patient?
@NilsPawlik has addressed the issue of a donor/recipient gender mismatch (it's not the most important factor, but it is something to consider). I thought I'd clarify the point about donor/recipient ...
- 3,188
6
votes
Which one is more harmful for your kidneys, drinking more or less water?
Background reading
Even though your fluid intake can be highly variable, the total volume of fluid in your body normally remains stable. Homeostasis of body fluid volume depends in large part on the ...
- 209
5
votes
Accepted
How can a ruptured ulcer all the way in the duodenum, cause kidney failure?
Your stomach may contain bacteria that are harmless as long as they are in your digestive tract, but are potentially lethal if they get into other organs. A ruptured ulcer means that it's possible for ...
- 911
5
votes
Accepted
Why does GFR have such a strange unit of measurement?
From the National Kidney Foundation:
Kidney function is proportional to kidney size, which is proportional to body surface area (BSA). Adjustment for BSA is necessary when comparing a person’s GFR to ...
- 488
5
votes
Blood in urine without seeing it...?
Yes. what you are describing sounds like microscopic hematuria (1). Sometimes red blood cells(RBC) are not numerous enough to be visible in urine. Yet, when tested, RBCs are detected.
(1) http://www....
- 116
5
votes
Accepted
Why does caffeine raise your blood pressure when it's a diuretic?
Caffeine increased plasma renin activity by 57 per cent, plasma norepinephrine by 75 per cent and plasma epinephrine by 207 per cent. Urinary normetanephrine and metanephrine were increased 52 per ...
- 13.2k
5
votes
Accepted
To what degree does a Vitamin D course mitigate the effects of Primary Hyperparathyroidism?
If you see a low vitamin D level in conjunction with a raised PTH level, then I think you need to think secondary hyperparathyroidism (HiPTH). But since vast numbers of most western populations have ...
- 13.2k
4
votes
Accepted
Is E. coli contagious?
Yes, E. coli is definitely contagious through direct contact. In fact your girlfriend's pyelonephritis could have come from you after sexual intercourse.
The general mechanism for this would be that ...
- 1,846
4
votes
Eating egg shells: advantages v.s. disadvantages?
Not allowed to comment, so just a partial answer from my part:
Salmonella bacteria are commonly found in the excrements of birds and egg shells are usually contaminated with them, and even let them ...
- 101
3
votes
Accepted
Can holding pee cause kidney damage?
My career choice (primarily Emergency Medicine) guaranteed that it would be necessary to postpone micturition on a regular basis. A nights-only colleague in our very busy ED would succinctly sum up ...
- 9,384
2
votes
Is it safer to take Naproxen once a day or twice a day?
Naproxen has a half-life of between twelve and seventeen hours.1 Constant steady-state serum levels of Naproxen are produced after four to five days..1 It stands to reason that the lower the dose the ...
- 1,390
2
votes
Does consuming Creatine harm the kidneys, or does it artificially elevate serum Creatinine?
Can it be falsely elevated? Yes: according to this study, creatine in the bloodstream peaks between 1 and 3 hours after consumption, depending on the form in which it is consumed.
Is it possible ...
- 2,003
2
votes
Quick way to determine if a medication is processed in the kidneys or liver?
drugs.com is a great resource. Go to the a Pro Edition header. Once you pull up the medication, scroll down until you find the Pharmacology Category. Once here, look for Metabolism and Elimination. ...
- 107
2
votes
Can I donate a kidney later and recieve one now?
"for someone else, of course"
Of course not. You haven't read or understood the rules. The point is that you donate a kidney and then the intended recipient gets a voucher to redeem your kidney in ...
- 1,094
2
votes
What does it mean for a medication to be "hard for the liver" or "hard on the kidneys"?
"Hard on the liver or kidneys" means that the medication is making this organ work harder, damaging it or so potent that the medication is harder to rid from the body.
Thinking about the liver:
...
- 2,965
2
votes
Supersaturation vs Undersaturation of the Urine | Kidney Stones
If you have kidney stones or you are at increased risk of developing them, ask a doctor if your urine is super- or under-saturated with any substance, such as calcium, oxalate, uric acid, cystine or ...
- 15.8k
2
votes
Accepted
How can a significant increase in survival not be interpreted as a significant decrease in mortality?
In the paper it says
Survival
Overall survival at day 180, as shown in Figure 3, was 42.9% (n = 24/56) vs 37.5% (n = 21/56) for terlipressin and placebo, respectively (P = .839).
That is a ...
- 6,154
2
votes
Accepted
Is salt bad for kidneys?
Having kidney stones alone entails a recommendation for low-sodium diet:
Reduce sodium: A high-sodium diet can trigger kidney stones because it increases the amount of calcium in your urine. So a ...
- 5,928
2
votes
Urine glucose testing for diabetes control
In short, glucose in urine is useful but not completely reliable test for diabetes mellitus, because:
It is possible to have diabetes mellitus without glucose in the urine.
Rarely, glucose in urine ...
- 15.8k
2
votes
Why does kidney disease result in some things being filtered out but not others?
Healthy kidneys practically completely excrete creatinine, which means it is not reabsorbed in the kidneys. In kidney damage, less blood is filtered by the kidneys (decreased glomerular filtration), ...
- 15.8k
1
vote
Accepted
Different names for eGFR measurement
The eGFR is calculated differently based on several factors, including sex and race. So there are different calculation formulas based on male vs female, and African American vs Caucasian. There are ...
- 86
1
vote
Accepted
Why do corticosteroids have few kidney-related side effects?
Corticosteroids block the enzyme Phospholipase A2 (PLA2) which catalyses the first step in arachidonic acid synthesis pathway. But, NSAIDs blocks activity of cyclooxygenases (COX 1 and COX 2).
So, ...
- 460
1
vote
When would estimates of renal function based on serum and urine measurements differ as greatly as one being normal and the other suggesting CKD 3b?
A lot of creatinine clearance calculations exist, and a lot depends on the patient (ethnic origin, sex, age, height, weight), so any discrepancies can be considered normal.
The point of multiple ...
- 1,513
1
vote
Why is Polycystic Kidney Disease(PKD) so difficult to cure?
Polycystic Kidney Disease (PKD) is caused by mutation in genes namely PKD1, PKD2, and PKHD1. In this disease cysts are formed in kidneys. The growth of cysts can result in kidney failure. Cysts may ...
- 460
1
vote
What can cause foamy urine other than protein?
Source: Bel Marra Health
Proteinuria: This is a condition in which protein is released in the
urine in high amounts. Protein is normally released in the urine but
in small amounts. When these ...
- 61
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