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6

Yes. Gene therapy is an active area of research; most gene therapy approaches that are studied use some sort of viral vector, those that don't are more the exception and it is unclear how several of those methods would be applied clinically. There have already been clinical trials of gene therapy with viral vectors, with mixed success. Edelstein, M. L., ...


5

Glucose and insulin could co-exist in the same container without reacting. Intravenous insulin has been used to treat hyperglycemia. There is a risk of severe hypoglycemia and even death after intravenous insulin (Diabetes Spectrum), which makes it inappropriate for use outside hospitals. What naturally happens during stressful physical work? Stress ...


3

Actually, ketoacidosis could occur also in Type 2 Diabetes. It's not common, but it's a possibility and should not be not omitted. In Type 2 Diabetes the insulin secretion is available but insufficient to meet the glucose needs. However, generally, can prevent sustained hyperglycemic states that could lead to ketoacidosis. When DKA occurs in patients ...


3

It is true that insulin stimulates the uptake of glucose, amino acids (from proteins) and fatty acids into the cells (PubMed, 2011: "Insulin effects in muscle and adipose tissue"). Diabetes.co.uk: Carbohydrates tend to be the largest factor accounting for changes in blood sugar. It’s worth noting that proteins can also affect sugar levels as well. ...


3

Triceba is actually Tresiba. It is a very long-acting basal insulin, that you take once a day. It is probably the best basal insulin today for people who do not have fast-changing basal needs like athletes: very insensitive to when you are taking it. Toujeo is a 3x concentrated version of insulin glargine -- i.e. 3x Lantus. It acts roughly like Lantus, but ...


2

The pump MiniMed 640G and the Contour Next Link 2.4 uses the IEEE 802.15.4 protocol with a proprietary data format. It uses the following operating frequencies 2420 MHz, 2435 MHz, 2450 MHz, 2465 MHz, 2480 MHz with a 5 MHz Bandwidth. There is yet no evidence of the compatibility of the MiniMed Connect with the 640g. If you're interesting in the ...


2

The manufacturer touts its ability to transmit data to its own apps via Bluetooth, so I'd say the answer is yes. The MiniMed Connect App for iOS is compatible for devices running iOS 8 and iOS 9 with Bluetooth® . The MiniMed Connect App for OS is compatible for devices running Android™5.0/5.1.1/5.1.2 (Lollipop) and Android™ 6.0/6.0.1/6.0.2 (...


2

GLP-1 is a hormone secreted by intestinal lining cells, which increases insulin sensitivity and slows down gastric emptying, which both help to control blood glucose levels after meals. There are diets that stimulate the secretion of GLP-1 from the gut. It's not that foods contain GLP-1, but some foods can stimulate its secretion. In some studies, virgin ...


2

The insulin price has grown significantly over the years, mostly from 2000-ish to 2014 for almost every major producer. The percentage of people that have to pay (and/or copay) more than 1000$ has for the first time since 1999 the 50% mark, and for a lifesaver medicine like insulin, this is a major problem that affects the 1.5 million people living in the ...


1

There have been few studies (on animals and humans) with multiple CGM sensors showing a more accurate estimation of the BG. [1][2] The site of application of the sensor, the discordance between multiple data sources and errors in the calibration of the sensors, are open challenges to be precisely addressed before having a system of this kind. Moreover, ...


1

The article you've linked mentions impaired magnesium uptake in diabetes mellitus type 2, not in healthy individuals. In cases when meals significantly affect bioavailability of a supplement, there will be likely an instruction on the information leaflet about the optimal time to take it.


1

It would be great to be able to keep an infusion set for that long. The reason why infusion sets cannot stay as long as CGM sensors is that the cannula used for injecting insulin in an infusion set is a lot more invasive and damaging than the very thin fiber that is used for measurement in a CGM sensor. CGM users often make their sensors last much longer ...


1

Unfortunately no, I have not found in my research any pumps which can be attached for a longer amount of time, although I did find a study which you may find relates to your question. Link to Study The following is the rationale behind site transfer and the suggested schedule. The manufacturers of IISs and insulin formulations used in insulin pumps ...


1

There are no inhaled insulin products that are long-acting, basal products. Today, Afrezza is the only type of inhaled insulin that is available, and it is of course bolus insulin. The only other inhaled insulin product that made it to commercialization, Exubera (PDF), only lasted a year, and was also a fast-acting bolus insulin. By its very nature, inhaled ...


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