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47 votes
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Does COVID-19 have a case fatality rate of 41%? Is this formula correct?

The definition of mortality rate that you've given does not match any practical definition I'm familiar with.* When people talk about the mortality rate of a disease, what they usually mean is the ...
Ilmari Karonen's user avatar
38 votes
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Why is the rate of circulating vaccine-derived poliovirus disease booming?

The short version is that in 2016 the polio vaccine changed. A more thorough explanation requires some background on the immunology of polio and its vaccines, which is not straightforward. Polio virus ...
timeskull's user avatar
  • 496
33 votes

Father gets chickenpox, but doesn't infect his two children. How is this possible?

If there was close contact, if the 90% rate is accurate, and if occurrence is independent in related individuals, then you would expect 0.10 * 0.10 = 1% of contacts with 2 potentially vulnerable ...
Bryan Krause's user avatar
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20 votes

Does COVID-19 have a case fatality rate of 41%? Is this formula correct?

The equation you use for mortality is only really useful in the very long term for a known disease, when most cases have resolved. It's not very informative in the short-term, when the vast majority ...
Bryan Krause's user avatar
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19 votes
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A cheap and easy inactivated vaccine for COVID-19

The only approved inhaled vaccine is the flu vaccine delivered intra-nasally. It uses a live attenuated virus. There are a whole list of people who should not receive it because it's a live virus, ...
Graham Chiu's user avatar
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14 votes

Does COVID-19 have a case fatality rate of 41%? Is this formula correct?

I'd like to chime in with an explanation of what exactly is wrong with the calculation offered in the question, rather than just saying "it's a wrong formula". Understanding the "whys" of the fallacy ...
Igor G's user avatar
  • 241
14 votes
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If a SARS-CoV-2 asymptomatic infected individual is exposed to a high viral load, could they develop COVID-19 disease?

What your government is proposing is a lot less than what was actually done in China. There, and perhaps that is still the case, large numbers of asymptomatic infected people were housed together in ...
Graham Chiu's user avatar
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13 votes
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Father gets chickenpox, but doesn't infect his two children. How is this possible?

To add to @BryanKrause's answer re: rare events happen all the time, the children are not out of the woods yet. The mean incubation time for a primary VZV infection (the clinical syndrome known as ...
De Novo's user avatar
  • 3,178
8 votes

Father gets chickenpox, but doesn't infect his two children. How is this possible?

Apart from not getting infected due to pure chance (as mentioned already) there is one highly probable explanation (explanation, not overall chance). People get, but don't show it: asymptomatic ...
LаngLаngС's user avatar
  • 6,908
7 votes

I have natural immunity to Hepatitis B. Do I pose risk to others?

The Hepatitis B core antibody test is positive for IgG but negative for IgM indicating that you had the hepatitis B infection a while ago. The negative hepatitis B surface antigen test means that they ...
Graham Chiu's user avatar
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7 votes
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Can the Coronavirus be spread via public toilet seats?

The virus causing COVID-19 infects the respiratory tract. It is spread in droplets of moisture when an infected person sneezes, coughs, and exhales. These droplets can be inhaled directly and can also ...
Bryan Krause's user avatar
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6 votes

Is there scientific evidence that spacing out vaccines have any positive effects?

There is evidence that delaying or refusing immunization puts children at risk of disease here and here. There is also evidence that delaying or spreading out MMR or MMRV in particular puts children ...
De Novo's user avatar
  • 3,178
5 votes

Are motorcycle helmets effective in preventing Corona?

It's better to use some guidelines from reputable sources rather than coming up with your own. The WHO does not recommend masks for healthy people in most circumstances, only when directly dealing ...
Bryan Krause's user avatar
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4 votes

Does being infected protect one from further infection?

In general: No. Having ulcers does not protect you from catching the flu. But that "no" is an oversimplification. The devil is indeed in the details. The innate immune system and the ...
LаngLаngС's user avatar
  • 6,908
4 votes

Are any infectious diseases 100% fatal?

First a clarification: The Milwaukee Protocol is now considered a failure. As a treatment option it not considered valid option any more. There are vaccines for rabies and port exposure prophylaxis ...
LаngLаngС's user avatar
  • 6,908
4 votes
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Are any infectious diseases 100% fatal?

Creutzfeldt-Jakob disease is considered 100 percent fatal. https://www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Creutzfeldt-Jakob-Disease-Fact-Sheet CJD is classified as a ...
Graham Chiu's user avatar
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4 votes
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Are motorcycle helmets effective in preventing Corona?

I think it's a great idea. It protects your eyes from respiratory droplets and keeps you from touching your face. I don't know how well it would work from keeping droplet from reaching your mouth, but ...
Quinn Zacharias's user avatar
4 votes
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What is daily sedation interruption for ventilated patients?

Yes, daily sedation interruption means a break in giving the sedation therapy. According to a 2014 Cochrane review: Daily sedation interruption versus no daily sedation interruption for critically ...
Jan's user avatar
  • 15.9k
4 votes

Does COVID-19 have a case fatality rate of 41%? Is this formula correct?

According to earlier answers, in this early phase of 2019-nCoV, Nd/(Nd+Nr) is an overestimator, and Nd/Nc is an underestimator. Since the currently bantered about rate matches the underwestimator ...
Mick's user avatar
  • 101
4 votes

Does bleach have to be diluted to be more effective to kill virus?

The text does not say that more diluted bleach is more effective at killing viruses (or bacteria, or yeast, for that matter). I'm quoting: ...A tenfold dilution of bleach, which subsequently mixed ...
PejoPhylo's user avatar
  • 141
4 votes

Does wearing gloves help against being infected with COVID-19?

My research search-fu is rather weak, and it's also quite likely that such research doesn't exist as it's not really how latex (or equivalent) gloves work. The gloves will support infectious agents ...
cpcodes's user avatar
  • 167
4 votes
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Does wearing gloves help against being infected with COVID-19?

If you are dealing with an infectious agent transmitted by bodily fluids, HIV or Ebola say, then gloves are an important element of personal protective equipment. Gloves help prevent infectious fluid ...
Charles E. Grant's user avatar
4 votes
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What receptors are targeted by the seasonal coronaviruses that primarily present as winter colds?

The story for these "common cold" coronaviruses is a slightly complicated. Mostly, these target different receptors (than the SARS family), except for NL63. The host receptor is a major determinant ...
got trolled too much this week's user avatar
4 votes

Why are antibodies not used as treatments for infectious diseases?

Where do you get the antibodies from? You could theoretically use donor blood from infected patients, but apparently it is still unclear if the transmission of those antibodies is safe. Also, those ...
Narusan's user avatar
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4 votes
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Does infectious hemophilia exist?

I would not call it hemophilia, but viral hemorrhagic fevers involve coagulopathy (quote from Wikipedia): small blood clots form in blood vessels throughout the body, removing platelets necessary for ...
Bryan Krause's user avatar
  • 14.2k
3 votes
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How useful are incubation periods when making a diagnosis of an infectious disease?

Incubation periods of common infections SKIN: Hand/foot/mouth disease..........3-6 days Measles, chickenpox..............7-21 days Rubella...................................14-23 days Lyme ...
Jan's user avatar
  • 15.9k
3 votes

Why is it not possible to get HIV by touching a contaminated surface?

There is a similar question from biology section(https://biology.stackexchange.com/questions/15712/how-do-viruses-or-bacteria-survive-outside-the-body-long-enough-to-spread) but your question focuses ...
kit's user avatar
  • 828
3 votes
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How to disinfect your laundry

A scholarly report discusses the matter Some years ago, a scholarly report was published. The report's "Appendix A" discusses, among other things, how to clean your laundry if there's a risk ...
3 votes
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What are the actual symptoms of the common cold?

Common cold is one of the labels used to describe non specific infection of the upper respiratory tract. Other labels include acute rhinitis, acute rhinopharyngitis or acute coryza. Upper respiratory ...
M. Arrowsmith's user avatar

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