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I am answering this almost two years after it was asked, but I hope an answer can still be useful! Hashimoto’s Disease You are correct that Hashimoto’s disease (also known as Hashimoto’s thyroiditis) is the most common cause of hypothyroidism in those aged over six. In younger children hypothyroidism is most often congenital. So yes, you almost certainly ...


3

The relation between TSH and free T4 is bidirectional and complex [1–4]. TSH stimulates the secretion of T4 from the thyroid gland. Immediately after being released into the bloodstream the vast majority of T4 is bound to plasma proteins including albumin, thyroxin binding globulin (TBG) and transthyretin (TTR, formerly called thyroxine-binding prealbumin or ...


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This also depends on the question if hypothyroidism is subclinical or overt. Recently, the European Thyroid Association has published a guideline on the management of subclinical hypothyroidism. In asymptomatic patients thyroid function tests (TFTs) should be repeated in 6 months intervals. Decisions shouldn't be based on TSH levels alone, but also on ...


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The hypothesis is that the free hormone is the fraction which is available for uptake into the cells and interaction with nuclear receptors. The bound hormone represents actually a circulating storage that is not immediately available for such an uptake. Since some drugs and illnesses can alter concentrations of binding proteins or the binding capacity, the ...


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This study from Australia https://www.mja.com.au/journal/2010/193/7/iodine-toxicity-soy-milk-and-seaweed-ingestion-associated-serious-thyroid indicates that iodine toxicity has been documented in people consuming soy milk made with kombu and illustrates the dangers of importing a foreign diet or manufactured food substance. We report a series of cases of ...


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Hypothyroidism - low levels of thryroid hormones are produced. There are many diseases where hypothyroidism arises. E.g. Graves Disease, Hashimotos disease. Early observations of Hypothyroidism showed two girls that were born without thyroid glands. "growth was severely stunted... very little power of locomotion; but could manage to walk from chair to ...


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