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The primary endpoint is the thing you design your study around. You choose a sample size based on a statistical power analysis, making sure you have enough participants that you will be able to detect a statistically significant effect if there is a large enough actual effect. Your p-value for your primary end point should be a good p-value if you've pre-...


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The answer to this question is for classification as Type 1 or Type 2 in adults (age >20 years) known (or believed) to have diabetes. Distinguishing Type 1 from Type 2 diabetes in children (age < 20 years) would require a different approach and has a separate literature. Here are citations and links to three publications that describe the use “...


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