Questions tagged [hematology]

Questions about the study, treatment, prevention, and diagnosis of blood-related diseases. See also [blood]

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Is there a modern term for "pessary cell"?

I was reading about the vitamin B12, and came across the description of a rare syndrome, with a mention of the "pessary cell" (a red blood cell in which the hemoglobin has disappeared from ...
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For what investigations is an RBC pipette used?

While performing total RBC count we have to use an RBC pipette.But for what other investigations we can use the RBC pipette?
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Why isn't there a notable "graft versus host" effect in lymphoma?

In other words, why don't we use allogenic hematopoietic stem cell transplantation (in general) for lymphomas? (with the exception of being occasionally used in highly selected lymphoid malignancies ...
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What is the normal range of platelet count and does this differ with age and sex?

I am trying to study the normal range of platelet counts and there are various sources out there on the internet on this topic. The article What do high or low platelet count levels mean? suggests ...
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Susceptibility of β-Thalassemia Heterozygotes to COVID-19

A recent study by medical researchers in Greece (https://pubmed.ncbi.nlm.nih.gov/34441941/) concluded that β-Thalassemia Heterozygotes (carriers) are more susceptible to severe symptoms of COVID-19 as ...
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3 votes
2 answers
246 views

Is there evidence that vaccine-related blood clots could be due to injection technique?

Recently, Danish health authorities including Denmark's SSI issued new guidelines for intramascular vaccination to be done with aspiration, in case some of the vaccine-induced blood clot cases are due ...
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Transplant of haematopoietic stem cells, how do they get back into the bone marrow?

I read about Hematopoietic stem cell transplantation. However, under "Graft types", "Autologous", it states: The patient's own stored stem cells are then transfused into his/her ...
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1 answer
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Does erythrocyte aggregation serve a useful function?

Wikipedia states that erythrocyte aggregation causes disease: Conversely, the presence of rouleaux is a cause of disease because it will restrict the flow of blood throughout the body because ...
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1 vote
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Chronic Myeloid Leukemia blast percentage

I'm trying to understand the oncogenesis of CML. I have a question about CFC cells and blast cells. Are those the same? I know that in the chronic phase of CML there is a blast percentage of 1-10% of ...
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Is low immature reticulocyte fraction after an acute hemolytic crisis normal?

All following data are theoretical and not real: A patient had a hemolytic crisis without anemia proven by elevated reticulocytes, elevated unconjugated bilirubin and normal hemoglobin and erythrocyte ...
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3 votes
1 answer
217 views

The role of growth factors in haemopoiesis

I am currently studying the textbook Hoffbrand's Essential Haematology, eighth edition, by A. Victor Hoffbrand and David P. Steensma. Chapter 1 Haemopoiesis says the following: SCF, TPO and FLT3 ...
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1 answer
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What happens when you put O+ blood in O- body

What happens when you put O+ blood in a O- body? I know O- can be put in everywhere but what happens, when you put a blood group in a body that would fit the group, but mismatches the rhesus factor. I ...
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Why is prothrombin time not used to monitor the effects of heparin?

Unfractionated heparin (UFH) is an anticoagulant that main works "by inactivating thrombin and activated factor X (factor Xa) through an antithrombin (AT)-dependent mechanism". Prothrombin time (PT) ...
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Why does hydrops fetalis occur in erythroblastosis fetalis?

I understand the pathophysiology of hydrops fetalis and erythroblastosis fetalis independently, but not why the edema occurs during erythroblastosis fetalis. For example, Langman's Embryology has ...
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1 answer
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How reliable is the determination method of reference ranges for blood tests?

A reference range is usually defined as the set of values 95 percent of the normal population falls within (that is, 95% prediction interval). It is determined by collecting data from vast numbers ...
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Citrate vs EDTA

What is the difference between the use of «citrate» and «EDTA» as an anticoagulant in medicine (I know that each one is used for some dosages but not the other, but I need to know why)?
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How is anaemia commonly diagnosed?

I am reading from the Australian Medical Council, Anthology of Medical Conditions (2003). Under the key objectives for presenting anaemia and pallor it says: "By considering the clinical context, ...
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High lyphocytes count in blood test

What is the lymphocytes counts limit which discriminates a recent infection from a CLL (Chronical Leukaemia Lymphocytosis)?
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Defining CPT 88184 Flow cytometry 1st marker

There are differing opinions in my office about how to bill for flow cytometry testing. To elucidate the difference, I need to give an example: A patient has blood drawn in the morning. The doctor ...
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1 vote
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Difference between Contusion, Haemorrage and Hematoma?

As per wikipedia these are the definitions: A contusion, commonly known as a bruise, is a type of hematoma of tissue[1] in which capillaries and sometimes venules are damaged by trauma, allowing ...
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Venous PO2 and anemic hypoxia [closed]

Why does venous PO2 decrease in anemic hypoxia? Shouldn't it be constant as PO2 is a measure of the dissolved oxygen?
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22 views

Side Effects of Monitoring Blood Stream for Weeks?

Is there currently some safe method to monitor arterial blood for weeks while "living normally"? Essentially, do doctors monitor some people's bloods contents by attaching some device that constantly ...
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2 votes
2 answers
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What should be done if a person is stabbed?

I have seen in almost all video-games and movies that when someone is stabbed by a sharp knife, the victim "takes out" the knife from his body. Does it help the victim in anyway? What should be the ...
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0 votes
1 answer
658 views

Hemeatology vs Hematology

Is there a difference between "Hemeatology" and "Hematology" as physician medical specialties? Or are these spelling variants, like "Haematology" vs "Hematology"?
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Plausibility of 30 gauge draw?

What are the risks, complications, and problems associated with using a 30 gauge needle to draw blood from someone with otherwise average veins? What is the certainty of hemolysis and would it be even ...
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3 votes
1 answer
36 views

Thrombotic events and antiphospholipid syndrome

If my understanding is correct, patients with antiphospholipid syndrome are at increased risk for thrombotic events 1 but in the same time, it is possible for these patients to have a thrombocytopenia ...
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1 vote
1 answer
633 views

Explanation of normal CRP during neutrophilia?

Let us assume we have a patient with this history and let us try to explain his/her normal CRP values on the end of this post given the fact of commorbid high fever and neutrophilia. The questions to ...
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2 votes
1 answer
42 views

Take different blood components from different people

My aunt needs blood urgently, but she happens to be 0- and neither the hospital nor family and friends are able provide this blood type to her. However, I was wondering if it makes sense to take only ...
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4 votes
1 answer
379 views

Decisions about anticoagulation in atrial fibrillation: how to factor in thrombocytopenia?

The benefit of anticoagulation for prevention of stroke in patients with atrial fibrillation has been well established. However, the benefit is always to be weighed against the risk, in this case, ...
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6 votes
2 answers
234 views

What did people do before the discovery of blood groups? [closed]

Today, we transfer our blood easily as we know our blood group. But what did people do before that discovery (in 1901 by Karl Landsteiner, then independently in 1906 by Jan Jansky and 1910 by William ...
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3 votes
1 answer
482 views

Does a person's healthy hemoglobin level vary from country to country?

Every time I get my hemoglobin tested, I am always below average. The doctors here say that the "average" has been calculated according to values from western countries, and that they don't apply to, ...
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7 votes
1 answer
253 views

How to deal with pale fingers in cold weather?

What is this condition called when one or more fingers go pale every time when being in a cold environment? Is it something that can be handled without having to relocate to exotic countries?
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9 votes
2 answers
5k views

Why do toenails turn black after impact?

What does it mean when a toenail turns black after a minor physical impact? Would this disappear by itself (it's already over a month)?
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18 votes
1 answer
321 views

Does blood donation reduce the risk of cardiovascular disease?

While answering this question about the possible detrimental effects of iron deficiency caused by frequent blood donation, I was reminded of a theory I heard long ago about a possible benefit of mild ...
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