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I have had a pain management course a couple of years ago - this was my research topic. As you pointed out the reasons are still unknown, also the treatment is basically aimed at treating symptoms an managing life with pain. This might be interesting to read if you are interested in this procedure called multimodal pain therapy [1]
The tender points are ...
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Uptodate discusses secondary failure after an initial response to drug therapy.
FACTORS LIMITING TREATMENT EFFICACY — Several factors may limit the degree of benefit achieved with prescribed medications or other interventions, including nonadherence to treatment interventions or comorbidities that cause peripheral pain and that require additional ...
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The following is what I have found, which shows promise on your hypothesis.
Yanmaz, at al. (2012) found
an increased prevalence rate of [Fibromyalgia Syndrome] in patients with [diabetes mellitus] type 2 and [rheumatoid arthritis]. There was no correlation between the prevalence rate of [Fibromyalgia Syndrome] and good [diabetes mellitus] disease control.
...
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Medicine, more than almost any other discipline, requires continuing education through the entire career. It changes rapidly, and whatever a doctor was taught 20 years ago in med school, or even 10 years ago at a conference, may not be true today. So if they're not keeping up, they're going to be ignorant on some issues. I've seen that myself more than once ...
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Here's a brief description of tests for babesiosis (PubMed, 2003):
A CBC [Complete Blood Count] is a useful screening test since anemia and thrombocytopenia are
commonly observed and parasites may be visualized on blood smear.
Conclusive diagnosis of this disease generally depends upon
microscopic examination of thin blood smears. Babesia frequently ...
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According to Drug.com, Fibromyalgia can cause pain and stiffness in the muscles and joints almost anywhere in the body, including the trunk, neck, shoulders, back and hips. People often have pain between the shoulder blades and at the bottom of the neck. Pain may be either a general soreness or a gnawing ache, and stiffness is often worst in the morning.
...
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There are several theories on the cause of fibromyalgia but you have to keep in mind that these theories about the causes of myalgia are merely speculative.
One of the theories states that it may be caused by the reduced effectiveness of the body's natural endorphin painkillers and the increased presence of a chemical called "substance P." Substance P ...
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In general, for various kinds of pain, you can re-train your brain to block some of the pain signals coming from your body in various ways: TENS, biofeedback, meditation, massage, guided imagery are some methods.1 Most use mental and physical distraction. Listening to music is an example of mental distraction; TENS is a physical distraction. Some you can ...
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