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Metformin has effects on many body systems and its many effects are not completely understood, as explained in this 2019 review article discussing use of metformin to treat Type II diabetes mellitus. Foretz, M., Guigas, B. & Viollet, B. Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus. Nat Rev Endocrinol 15, 569–589 (...


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This is a reasonably recent review of old and new treatments for polycystic ovary syndrome (PCOS). Bednarska S, Siejka A. The pathogenesis and treatment of polycystic ovary syndrome: What's new? Adv Clin Exp Med. 2017 Mar-Apr;26(2):359-367. doi: 10.17219/acem/59380. PMID: 28791858. https://pubmed.ncbi.nlm.nih.gov/28791858/ As indicated in this review, ...


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The hypothesis is that the free hormone is the fraction which is available for uptake into the cells and interaction with nuclear receptors. The bound hormone represents actually a circulating storage that is not immediately available for such an uptake. Since some drugs and illnesses can alter concentrations of binding proteins or the binding capacity, the ...


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As you found, HbA1c is glycated Haemoglobin (Hb) the A1c bit refers to the type of Haemoglobin. POCT is Point of Care Testing. (See https://dx.doi.org/10.1177/1932296814538940 IFCC is International Federation of Clinical Chemistry and Laboratory Medicine (https://www.ifcc.org/) a standardisation program for HbA1c testing DCCT is the Diabetes Control and ...


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