9 votes
Accepted

Should chronic low cortisol be treated if the patient has no symptoms?

The disease associated with low cortisol is known as adrenal insufficiency (so-called because the adrenal glands are responsible for cortisol production). Morning cortisol is not a definitive test for ...
Susan's user avatar
  • 4,416
9 votes

Is adrenaline a coctail of hormones, rather than one hormone?

Adrenaline = epinephrine. Different name, same chemical. "Adrenergic receptors" is perhaps where things get more confusing. That is a family of hormone receptors (α1 α2 β1 β2...) that respond to ...
DoctorWhom's user avatar
  • 5,814
8 votes
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What happens to a woman if she takes testosterone?

The long-term impact of testosterone on women's health is still not clarified enough, so it's not easy to predict them exactly. Some common side-effects of high testosterone level are acne and ...
Elmer Hoffman's user avatar
7 votes
Accepted

What are the long-term side effects of melatonin?

In long term studies, the effects have been mixed but mild. In hemodialysis patients, after about six months - melatonin no longer seemed to have physiologic effects but could still be detected at ...
Praxiteles's user avatar
6 votes
Accepted

Could a high TSH level mean a problem with the pituitary gland?

When a physician is studying someone for a suspected disorder related to the thyroid hormones, he/she should not only study the thyroid, but evaluate the hypothalamus-pituitary-thiroid endocrine axis ...
MikeKatz45's user avatar
6 votes
Accepted

Why hormone replacement (e.g. Levothyroxine) for high TSH levels when T3 and T4 levels are normal

The lab parameters you describe (slightly elevated TSH, normal T3/T4) in isolation are an indication of latent hypothyroidism. In general, this is interpreted as a thyroid gland not functioning ...
Narusan's user avatar
  • 6,901
6 votes
Accepted

How quickly does ACTH deficiency cause adrenal gland atrophy?

Some Endocrinology The hypothalamic-pituitary-adrenal (HPA) axis can be summarised in this diagram, with the hormones released at each level creating a negative feedback loop with the level above. ...
Chris's user avatar
  • 3,332
5 votes

“There is a very strong correlation between consuming dairy products — such as milk — and acne, skin breakouts and aging.”

If the main thrust of the question is indeed expressed in the title and tags of the question: Q “There is a very strong correlation between consuming dairy products — such as milk — and acne, skin ...
LаngLаngС's user avatar
  • 6,907
5 votes

“There is a very strong correlation between consuming dairy products — such as milk — and acne, skin breakouts and aging.”

These are biologically plausible effects supported by moderate quality observational evidence. As a personal aside, I do not believe there is enough evidence for harm to recommend eliminating dairy ...
De Novo's user avatar
  • 3,178
5 votes
Accepted

What are the benefits of high testosterone in men?

What are the benefits of high testosterone in men? what benefits does high testosterone actually entail? Mental health discussion would be interesting too, if there's any association ...
Facebook's user avatar
  • 449
5 votes

Does hyperthyroidism affect serotonin levels?

Thyroid function and serotonin activity are highly linked. Serotonin stimulates hypothalamic TRH (Thyroid Releasing Hormone) production, leading to an increase in TSH (Thyroid Stimulating Hormone) ...
Taylor's user avatar
  • 958
5 votes
Accepted

What is the relationship between hormones and proteins?

According to this book "Endocrinology: An integrated Approach", which is freely available via the NCBI Bookshelf (http://www.ncbi.nlm.nih.gov/books/NBK20/) in Chapter 1: Hormones can be derived from ...
Felipe's user avatar
  • 882
4 votes

Lab test result meaning

Measurements will always have measurement errors, we distinguish between systematic errors and statistical errors due to noise, or other random effects than on average are zero. Usually the former ...
Count Iblis's user avatar
  • 2,270
4 votes
Accepted

Low dose and high dose dexamethason supression test

In a dexamethasone supression test, it is measured whether given the patient dexamethasone leads to lowered cortisol levels. Lowered cortisol levels are the normal response to dexamethasone; if the ...
YviDe's user avatar
  • 6,992
4 votes

Does a hormone PTSH exist?

In short: It seems, there is not enough evidence to say that parathyroid-stimulating hormone secreted from the pituitary gland exists in humans. A) Parathyroid Stimulating Hormone (PTH) Some texts ...
Jan's user avatar
  • 15.9k
4 votes
Accepted

Why is adrenaline typically not prescribed as pills?

From Furukawa, C. T., & Lodewick, M. J. (2007). β-adrenergic agonists. In Allergic Diseases (pp. 335-342). Humana Press.: Epinephrine has both α- and β-adrenergic actions, which make it the drug ...
Bryan Krause's user avatar
  • 14.1k
3 votes
Accepted

Does elevated potassium lead to elevated cortisol?

National Institutes of Health - Health Professionals Fact Sheet on Potassium Dietary potassium In healthy people with normal kidney function, high dietary potassium intakes do not pose a health risk ...
Gordon's user avatar
  • 392
3 votes

What is the relationship between hormones and proteins?

A protein is a long folded chain of amino acids. A chain of two or more amino acids is called a peptide. Now, hormones are grouped into three classes based on their structure: Peptides: like insulin ...
Lamia Kouba's user avatar
3 votes
Accepted

Refrigeration for peptides

As I've said in the comments it depends on the specific product, so I can't really give a straight yes or no answer. But I'll give a few examples, and I hope that will help. Peptides that are already ...
Lucky's user avatar
  • 2,833
3 votes
Accepted

What is the rationale of using Metformin in Pre-Diabetes and Type 2 Diabetes?

Metformin has effects on many body systems and its many effects are not completely understood, as explained in this 2019 review article discussing use of metformin to treat Type II diabetes mellitus. ...
Diana Petitti's user avatar
3 votes

What is the specific relationship between Prehormones, Prohormones and PreProHormones?

I agree with Bryan Krause that the terms are used inconsistently in the literature. However, at least to a subset of authors (and to me), the biologic difference is clear. Preprohormones ...
Ian Campbell's user avatar
  • 3,256
2 votes

Does inhibiting prolactin levels cause any health problems?

Prolactin is a peptide hormone that, in addition to modulating the hypothalamic–pituitary–gonadal axis, functions as a cytokine in the immune system and as a growth factor in the vascular system ...
Andrew McKinlay's user avatar
2 votes
Accepted

"Narrow" Pure Androgen-secreting Adrenocortical Adenoma

These patients were all female, and the tumors are described as exceedingly rare. Were you looking for males? https://www.ncbi.nlm.nih.gov/pubmed/14668717 METHODS: A retrospective chart review ...
Graham Chiu's user avatar
  • 13.3k
2 votes
Accepted

Thyroid Peroxidase (TPO) Ab Test- normal or abmormal

Normal. A result of 9 where the reference range is 0 - 34 indicates that you're within the normal range. For this test, an abnormal result would be a value over 34 because it's not possible to have a ...
Highly Irregular's user avatar
2 votes
Accepted

Is there any risk from eating meals before/after HGH shots?

1) Human growth hormone (HGH) shots, meals and glucose and insulin spikes. HGH shots increase blood glucose and therefore insulin, both of which can be further increased by having meals shortly ...
Jan's user avatar
  • 15.9k
2 votes

If a man occasionally wakes up after five hours of sleep, is it safe for him to take melatonin even though the night is almost over?

According to research published in the British Journal of Clinical Pharmacology and cited below, the serum half-life of immediate release melatonin ranges from 0.54 to 0.67 hours. Assuming you take ...
Lucas Thomas's user avatar
2 votes

Impact of Various "Feminizing" Hormones on Metabolism

There is peer-reviewed scientific research article "Sex hormones, appetite and eating behaviour in women" by Angelica Lindén Hirschberg from Karolinska Institutet, which states already in abstract ...
Zui Muss's user avatar
2 votes

Amount of phytoestrogens in processed soy like tofu

Below are the amounts of phytoestrogens content calculated from results of several analyses. DAIDZEIN Tofu - 76µg/g Soy sauce - 8µg/g Soy milk - 18µg/g Tempeh - 190µg/g Soy hot dog, tempeh burger - ...
Prince's user avatar
  • 1,868
2 votes
Accepted

Can an elevated TSH and normal T3 and T4 biologically cause fatigue?

These hormones and their interconnectedness are quite complicated in al their details. TSH is not only connected to the regulation of T3 and T4. TSH receptors are found elsewhere, not least in the ...
LаngLаngС's user avatar
  • 6,907

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