13 votes
Accepted

Do Benadryl and Loratadine contain the same active ingredient?

No, they do not contain the same active ingredient. Benadryl (trade name) is also known as diphenhydramine (generic name); loratidine (generic name) is also known as Claritin (trade name). Both drugs ...
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  • 4,355
7 votes
Accepted

Why isn't Tylenol safe?

The main risk of Tylenol (aka acetaminophen/paracetamol) is liver damage, as this article from the FDA advises: This drug is generally considered safe when used according to the directions on its ...
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  • 1,390
7 votes

Baby aspirin interaction with other NSAIDs

Is it right and safe to prescribe this combination (NSAID like diclofenac + baby Aspirin) specially with the knowledge that this combination gonna be used for a long time? While NSAID are ...
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  • 905
6 votes
Accepted

What are the health risks of drinking Diet Coke while chewing Mentos?

There is a myth that drinking Diet Coke while chewing Mentos causes your stomach to explode, though this has been disproved by MythBusters and Snopes. Both sources say that the reason for the ...
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  • 7,727
5 votes
Accepted

ADD medication (Dexadrine) safe to drink with low-caffiene (Mountain Dew)?

Micromedex does not list any precautions or patient educations notes for Dexedrine and caffeine. However both substances can have an effect on heart rate and blood pressure. Large amounts of caffeine ...
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4 votes

Quantify third-hand smoke exposure risk

The following are studies which indicate cancer risks from third hand tobacco smoke which to me seems non-ambiguous. Sleiman, M., Logue, J. M., Luo, W., Pankow, J. F., Gundel, L. A., & ...
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  • 5,872
3 votes

Is the interaction between alcohol and benzodiazepines additive or multiplicative?

The common saying that alcohol (ethyl alcohol in alcoholic beverages) and benzodiazepines shouldn't be consumed together is well-recommended considering that both compounds fall under the Central ...
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  • 411
3 votes
Accepted

What is it like to go under with Succinylcholine?

Succinylcholine, or Suxamethonium chloride, is an 'interesting choice' for this kind or purpose. As a muscle relaxant with a relatively short duration it will paralyse the victim, cause breathing to ...
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  • 6,747
3 votes

Why isn't paracetamol routinely combined with n-acetylcysteine?

Several combinations between analgesics and other compounds could be interesting for medical treatment and used in pain treatments, however, the logic isn't only effectiveness. For a medication to be ...
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3 votes
Accepted

As ICD is a global standardization of diseases, is there a global standardization of drugs and if not, why?

I think the closest thing to a "standardization of drugs" are the pharmacopeia: USP European Pharmacopoeia Japanese Pharmacopoeia (just some examples) As you will notice, these are not global ...
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  • 12k
3 votes

Do doxycycline and ciprofloxacin decrease each others effectiveness?

I searched for an answer on several different levels and here's what I found: FDA's presrcibing information for CIPRO(R) and for DORYX(R). Neither document mentions an interaction between these two ...
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  • 1,598
2 votes
Accepted

Does Mirena IUD help with acne control too? Is it safe to take concurrently with Accutane?

When someone is considering to take 2 drugs both of which can have severe side effects, he/she should discuss this with a doctor, so this part of the question CANNOT be properly answered here. Mirena ...
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  • 15.6k
2 votes
Accepted

Can ibuprofen and paracetamol be taken together?

Yes, it is safe. The mechanism that ibuprofen and paracetamol use are different and don't interact negatively. In fact, the two drugs (medicines) can be used in conjunction for a synergistic effect so ...
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2 votes

As ICD is a global standardization of diseases, is there a global standardization of drugs and if not, why?

The idea that the International Statistical Classification of Diseases and Related Health Problems (ICD) forms an international standard on health problems is contentious within some groups of people ...
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  • 5,872
2 votes
Accepted

Why are some tablets Telmisartan, Amlodipine and Hydrochlorothiazide bilayered and some are not?

There are good reasons why some drugs are bilayered. A company could decide to produce a bilayered drug formulation for the same drug if it's necessary to produce a formulation in which the drug in ...
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  • 186
2 votes

Does L-theanine increase caffeine's half-life?

The mechanism of action of L-Theanine is not quite well understood and at some degree recent studies find themselves in contradictory with the results, nevertheless I think the essencial is this ...
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  • 473
1 vote
Accepted

Is there a standard about maximal caffeine concentration for synergistic painkiller preparations?

According to the U.S. Food and Drug Administration (FDA), 2017: The GRASE dose for caffeine is established in the Stimulant Final Monograph as 100-200 mg not more often than every 3-4 hours. ...
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  • 15.6k
1 vote
Accepted

Why many usually-very-painful medical processes aren't done under conscious, generally painless-painkilling?

Lidocaine1 is not categorized as a painkiller but as a (local) anesthetic; it can be used during minor procedures where the patient has full awareness by injecting it to the preferred site of action. ...
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  • 34
1 vote
Accepted

Dextroamphetamine vs Dextroamphetamine Salt Combo

In order to substitute lawfully, the 2 drugs must be bioequivalent and in the same dosage form. Therefore the 2 drugs not only must be chemically equivalent, but also therapeutically equivalent. In ...
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1 vote

Taking Benadryl after Claritin

Benadryl (aka diphenhydramine) is strongly anticholinergic1. That means it blocks acetylcholine activity in the body's cells. It does this by binding with the cells' acetylcholine receptors, which ...
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  • 1,390
1 vote

Do dietary potassium and sodium interact with eachother?

Dietary sodium stimulates the excretion of potassium into the urine and potassium stimulates the excretion of sodium, but when consumed in usual amounts, this does not result in abnormal blood ...
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  • 15.6k

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