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5

I would say that the guideline gives physicians quite a bit of leeway in determining a death is caused by COVID-19. The standard is not "any positive test + death = COVID-caused death"; it gives 2 necessary criteria and two exclusions: a clinically compatible illness in a probable or confirmed COVID-19 case unless there is a clear alternative ...


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I'm not fully sure I understand your question but I believe the answer is "yes", that the syncytia-inducing S proteins are different from the S protein fragments presented by MHC molecules. Remember, in the antigen presentation pathway, some proteins are cleaved into peptide fragments inside the cell, then those peptides bind to MHC molecules and ...


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I'm not sure on your question - the protein produced from translation of the viral mRNA is all the same. Vast quantities are produced to generate the amounts needed to make up the numerous progeny virions. Some of this protein will end up at the cell surface, some will end up on the MHC, but it is all the same protein. There is no differentiation during ...


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