63

Your question contains a lot of misconceptions. A cure is definitely possible A cure could be found, proved, and proved safe, more quickly than a vaccine People and firms that could be working on cures are choosing to work on vaccines None of these are correct. Most virus-caused diseases have no cure: colds, Zika, Dengue, and so on. A tiny handful have ...


31

The seasonal coronaviruses attach exclusively to cells with a ciliated epithelium. Coronaviruses invade the respiratory tract via the nose. After an incubation period of about 3 days, they cause the symptoms of a common cold, including nasal obstruction, sneezing, runny nose, and occasionally cough (Figs. 60-1 and 60-2). The disease resolves in a few days, ...


23

Drugs are typically small molecules that interfere with some chemical process in the disease causing microbe, and therein lies the rub. Bacteria, fungi, protozoa, worms, etc. are sustained by their own complex systems of chemical reactions, largely independent of chemical systems that sustain us. That makes it easier to find a chemical that attacks ...


12

The confusion exists because there are conflicting pronouncements from various authoritative sources but also conflicting pronouncements from the same authority. Covid-19 is a respiratory infection spread by droplets that can be aerosolized (nuclear droplets) in certain situations such as by flushing toilets or in certain medical procedures such as ...


11

Covid-19 is the result of a zoonotic outbreak from bats to an intermediate ( and unidentified host ) thence to humans. It is thought that bats don't suffer the disease themselves as they carry low levels of virus but the intermediate host modifies the virus, and amplifies it so that it vastly increases the amount of virus that can shed into the environment ...


10

This is something people have been studying since 1847 when Ignaz Semmelweis hypothesized that childbed fever was caused by physicians assisting at deliveries without cleaning their hands (sometimes coming directly from autopsies or cadaver dissections). Since then there have been thousands of experiments performed to find the best methods of hand ...


9

Roman Zieliński seems to be intentionally misleading you by making an implausible circumstance that is technically possible sound like a likely outcome. This strategy is not unusual among people who argue against vaccination, because they have very little actual science to argue based on. The Central Dogma as stated by Crick says nothing about RNA vs DNA. It ...


7

TL;DR: please WEAR A MASK! (unless your nearby hospitals are out of it, in which case give your masks to them and stay at home) The link you mentioned provides the reason that the CDC likely has in mind (though I agree it doesn't identify it clearly as the reason): The worldwide supply of masks is limited. It's critical that we use them appropriately. [...


7

I don't believe we have the data to say that vaccines will be deployed earlier than an effective treatment. Vaccine technology is old technology and the go to for most infectious diseases as there is a desire to prevent preventable illness. However, HIV was discovered in 1984 but we still don't have a vaccine against it though we have effective treatments. ...


7

To supplement Bryan's answer (although I'm not going to say anything fundamentally different here), according to their proponents, mRNA vaccines are considered the safest genetic vaccines (in this integration regard) because mRNA transcription ("transfection") to proteins happens outside the nucleus. Quoting from a review mRNA vaccines do not ...


6

Let's not get ahead of ourselves here.. chloroquine/hydroxychloroquine (and possibly in concert with azithromycin) have been touted over the past few days as a possible treatment regimen. And there's some cause for that - the antiviral properties of chloroquine/hydroxychloroquine in vitro are broad and it's been trialed against various things (HIV, Ebola ...


6

You're asking some completely different questions here from sources talking about completely different aspects of antibody-mediated immunity. The first statement, from WHO, is talking about people who have antibodies now and whether they will have immunity in the future. Antibodies are produced by particular immune system cells. Someone can recover from ...


6

At this point in time no one can say for sure why many people appear to have asymptomatic infection, and figures range from 20-80% though part of the problem appears to be from false positives in antibody tests. Nevertheless there have been large numbers picked up on rt-PCR who carry the virus but at the time do not show symptoms. Some, if not most, go on ...


5

You should read the whole article: Things You Should Never Microwave ... - Clothing and other large fabric items The problem with microwaves is that they are not heating any item put inside them homogeneously but create "hot spots" instead. The image shows a simulation of the electric field inside a microwave oven (taken from wikipedia). Therefore, ...


5

The reason why many people who contract COVID-19 are asymptomatic is simple. It is because your immune system can kill the pathogen before you show symptoms. In other words, your body overwhelms the virus before it takes over larger areas of your body. The answer to your second and third question is yes and no. Most people, that recover quickly without ...


5

This question may a bit too broad (e.g. there are some separate questions about Covid-19 and food) but on the topic of transmission in an office-like setting there have been some studies/reports, some more systematic/formal than others. I know of a study in South Korea in an office building, call center more precisely, (this has received widespread press ...


4

To add to Philipp Leitl's good and cautionary answer: Microwave ovens work by causing polar molecules in the food being cooked, e.g. water and fats, to rotate, according to: Why does microwave heat up things so much more quickly than visible light? This rotational movement provides the heating effect. I would not be sure that the chemical make-up of ...


4

Since the virus replicates via human cells, how do you expect it to proliferate inside a refrigerator? And if you had human tissue (lungs, hearts, kidney, bowel) in your fridge, it still needs to be alive to proliferate as it hijacks the living cells intra-cellular machinery. So, you're not going to get any more virus out than you put in. Therefore if you ...


4

One of the issues with COVID-19 is the fact that it is transmissible even by people who are asymptomatic. You've probably heard about R0, which is the basic reproduction rate of a disease, that takes into account transmission modes and contact rate, among other things. I'm not an epidemiologist, but I'm operating under the assumption that someone who is ...


4

The text does not say that more diluted bleach is more effective at killing viruses (or bacteria, or yeast, for that matter). I'm quoting: ...A tenfold dilution of bleach, which subsequently mixed with an equal volume of RSV-containing medium (so in fact a twentyfold dilution) eradicated all of the virus. A 100-fold dilution of bleach killed 100% of the ...


4

I should add here that there has been a case of ARDS reported for the alphacoronavirus 229E (i.e. a "common cold" coronavirus) in 2018. But ARDS occurrences are of course, much less common in these "common colds" than in Covid-19 infections. The case report for 229E discusses the few other such occurrences: HCoV-229E has been associated with bronchitis, ...


4

This must depend on the local situation. At the beginning of the pandemic Japanese Hospitals were admitting PCR positive asymptomatic patients. Then as the disease spread Chinese authorities in Hubei were creating field hospitals (sixteen Fang Cang hospitals in Wuhan ) to house the less symptomatic patients and leaving the hospitals with ICU facilities to ...


4

Masks with exhalation valves are meant to be used to protect against particulates like sawdust or smoke. They must not be used in a pandemic because a large part of the usefulness of masks is preventing people who are infected and don't know it from spreading the virus. If you have an exhalation valve on your mask you're exposing everyone around you. Public ...


4

You are confused. The VUI-202012/01 strain has some 17 mutations, some of which have been seen separately before. See COG UK summary: COG UK suspects that that many mutations have accumulated in a chronic case of infection which served as a "living lab". ECDC give this approximation of the spread of the new kid: In contrast G614 has been dominant ...


3

Household bleach is usually at 5% concentration of sodium hypochlorite. Data from disinfection of other coronaviruses indicates that dilutions of 1:100 are still effective. Higher concentrations of bleach are difficult to manage as they release chlorine gas and are irritant to the mucous membranes, lungs and eyes. The bleach works as a potent oxidizer of ...


3

does that mean every one in the world at some point has to get infected until a vaccine is invented? No. There are many infectous diseases which are only regional, or have been almost eradicated. Countries free of (this or that) disease need to act quickly on imported cases, if the disease is highly infectuous. On the other hand, if the spread of a ...


3

University of Washington (UW Medicine) suggests Testing Criteria on their site: https://covid-19.uwmedicine.org/Pages/default.aspx The following patients with COVID-19 symptoms should be tested for COVID-19: • Patients hospitalized with severe lower respiratory illness • Healthcare workers • Patients in other public safety occupations (e.g., law enforcement,...


3

When you say slow down the rate of transmission indoors, most countries that I know of with this condition are in lock-down or practicising social distancing to reduce the risk of spread. So, I presume that you must mean the spread of disease from an infected person to another in the same household. We have some data to suggest that virus viability is ...


3

It's true for practically every virus that they are viable for longer at lower temperatures. Unless they are cultured, storing [freeze dried] viruses below -20C is the only way to keep them viable for decades. (More typically they are held below -70C as a safety margin.) The ability to store viruses for long periods of time with minimal loss of viability ...


Only top voted, non community-wiki answers of a minimum length are eligible