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The clinical trial for the treatment you're talking about is on ClinicalTrials.gov here: https://clinicaltrials.gov/ct2/show/NCT03410901 It says the trial started in April 2018, and is expected to end in October 2020; these estimates are sometimes off and it's possible other things like the COVID-19 pandemic could impact the timeline, as well as unexpected ...


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Firstly Stanislaw Burzynski (who I presume to be the "one person" you mention) isn't the only person to investigate antineoplastons, Ogata et al did a trial published in 2015, although that work is not without problems, it was completely unblinded for a start. Hardly top drawer science. Secondly what Burzynski does isn't really clinical trials, he ...


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The basic structure of tooth consists of Outermost layer, enamel Next layer, dentin Innermost vital, vascularised tissue, pulp Hard tissue layer covering the root ( root doesn't have enamel), i. e. Cementum Reference Now enamel is a non vital tissue, having no cells, and vasculature. Reference Similarly dentin too doesn't have any cells, but has processes ...


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The average human is rumoured to have around 30,000,000,000,000 cells in their body. Apoptosis kills around 60,000,000,000 cells a day. This is 0.002%, so I imagine a 5% kill rate would be at least fairly painful.


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When looking around to see if this exists all I found were articles about how to target cancer cells specifically, nothing about targeting all cells and using the fact that cancer cells divide quicker to distinguish between them. You've misinterpreted how radiation/chemotherapy work. Both are "poisons" in that they cause DNA damage or otherwise irreparably ...


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This is actually answered in my response to your previous question, but it is a good concept that can take some work to wrap one's head around, so I will go in more depth. Please note that no one other than the individual's physician can advise on what next steps to take once a positive finding is identified - regardless if the positive result was found ...


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In many cases yes, a tumor must be biopsied in order to determine exactly what type of tumor it is. Advanced imaging can, in some cases, diagnose a specific type of tumor. However, there are many chemotherapy agents that are very specific not just to a particular tumor, but a particular tumor with certain genetic factors (such as presence or lack of specific ...


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Not sure why I didn't think of this earlier, but back pain that is worse at night due to metastatic cancer to the spine is caused by tumor compressing spinal cord when lying on your back. Anything that worsens the compression, such as "when you cough, sneeze or go to the toilet", will also worsen the pain. Source: https://www.cancerresearchuk.org/...


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Studies with high resolution intravital microscopy have shown that cancer cells in circulation can deform and squeeze through vessels as small as capillaries, which are usually 5-10 µm in diameter. A large number of factors contribute to whether a circulating tumor cell actually forms a metastatic tumor, including characteristics of the tumor cell, ...


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Cancers that are derived from blood-related cells can still involve tumor growth - it is wrong to say they do not manifest as solid tumors. Leukemia does not typically manifest as solid tumors and is probably what you were thinking of but is not on your list. Drugs that inhibit angiogenesis can stop/slow the growth of such tumors. Jakob, C., Sterz, J., ...


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A double-blind crossover study of placebo and the antiestrogen tamoxifen in ten men with gynecomastia of diverse etiology showed that: The reduction of breast size was partial and may indicate the need for a longer course of therapy. A follow-up examination was performed in eight out of ten patients nine months to one year after discontinuing placebo and ...


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All chemical reactions including killing cancer cells with poisons occur at approximately twice the rate per ten degrees. So reducing the scalp by ten degrees while chemo is occurring will reduce the rate of poisoned hair follicles by half during the procedure. https://www.chemguide.co.uk/physical/basicrates/temperature.html


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As indicated in the first answer, the first figure is for a clinical trial. This kind of figure is often called a "Clinical Trial Design Schematic" or simply a "Schematic for a Clinical Trial." Here are some other examples of trials that present such figures and label them as “clinical trial design schematic” or “schematic.” https://www....


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The first one is a Treatment Schedule from the Acute Myeloid Leukemia - Berlin–Frankfurt–Munster Study of 2004. The image can be found on page 39 of the article found here: Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004 Ursula Creutzig, Martin Zimmermann, ...


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I think 'I' represents Intravenous infusion as it is mentioned in Clinical trial information sheet.


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The authors are fitting a regression model. It is common in regression with factors as predictors to consider one level of the factor as a "reference" level. Every other variable in the model expresses some difference relative to that reference level. Ultimately the choice of reference doesn't matter that much for the model, as long as appropriate ...


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Does it mean "typical survival shown by this kind of therapy in clinical trials?" Yes. They are saying that this is a typical median survival in trials of this treatment, but that real-world survival is lower. Therefore, there is a gap between real practice and the trials. Furthermore, that makes it unclear if the trials showing a benefit ...


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One study from 1985 shows that people who were in the top quintile of green and yellow vegetable intake had relative risk of 0.3 of dying from cancer compared to the lowest quintile. As far as risk for developing cancer, in another study from the 1980s, smokers who ate more carrots were less likely to develop lung cancer (this effect was only seen in smokers,...


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It's not a given, that they are not useful in solid tumors (also lymphoma are accounted among the solid tumors). There are pyrimidine-like antimetabolites, e. g. 5-FU: https://en.wikipedia.org/wiki/Fluorouracil, while some purine antimetabolites were in development, see e. g. here: https://www.ncbi.nlm.nih.gov/pubmed/4066218. There are some approaches that ...


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1) Global incidence for HCC, 2018: What is the global incidence of hepatocellular carcinoma (HCC) worldwide? (Medscape, 2019): Worldwide, liver cancer was the fifth most common cancer and the third most common cause of cancer deaths in 2018, with an estimated 841,080 new cases and 781,631 deaths. The incidence was highest in East Asia, at 17.7 per ...


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There is a large difference in survival depending on whether the cancer was caused by HPV or ( probably) tobacco/alcohol. The HPV cancers have significantly higher survival rates. I am surprised the ACS information does not point out this difference. I was diagnosed with oral cancer about 9 years ago ( age 74), I had likely had it for a couple years before ...


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