9

The disease associated with low cortisol is known as adrenal insufficiency (so-called because the adrenal glands are responsible for cortisol production). Morning cortisol is not a definitive test for the diagnosis of adrenal insufficiency.1 That is because cortisol varies according to a circadian rhythm (i.e. with your body's sleep-wake cycle). The x ...


6

At this point in time no one can say for sure why many people appear to have asymptomatic infection, and figures range from 20-80% though part of the problem appears to be from false positives in antibody tests. Nevertheless there have been large numbers picked up on rt-PCR who carry the virus but at the time do not show symptoms. Some, if not most, go on ...


5

The reason why many people who contract COVID-19 are asymptomatic is simple. It is because your immune system can kill the pathogen before you show symptoms. In other words, your body overwhelms the virus before it takes over larger areas of your body. The answer to your second and third question is yes and no. Most people, that recover quickly without ...


3

Yes, it is possible to have no symptoms and be infected, various sources, e. g. https://www.ncbi.nlm.nih.gov/pubmed/32179137. As for testing after 'clearing the infection', this would be what a serological scarring test would look for, e. g.: https://www.statnews.com/2020/03/27/serological-tests-reveal-immune-coronavirus/ https://www.contagionlive.com/...


3

Asymptomatic refers to a state of no symptoms at a particular time. One can be asymptomatic in the incubation period, and/or, in the period following the infection as shown by positive rtPCR which shows that an infection is present. It doesn't mean that they'll remain asymptomatic forever. Presymptomatic means during the incubation period for the virus ...


2

Why is surveillance not implemented at scale in the USA? Not enough test kits. If the USA does not have testing at scale, why is this the case? Didn't go through MERS and SARS, unlike South Korea. E.g see https://www.theguardian.com/world/2020/mar/15/experience-of-sars-key-factor-in-response-to-coronavirus


2

As of May 2020, evidence suggests that coronavirus infection periods are related to viral load, viral shedding and symptoms of disease (although some asymptomatic people can still spread the infection), such as coughing, which would disperse the virus into the air. In one case series of mild infection, 90 percent had negative viral swabs at 10 days after ...


2

I'm not aware of any study that only looked at viral loads in asymptomatic infected persons but if you look at mild to severe patients, their viral loads all tend to follow a similar pattern whereby 21 days the viral load drops below the threshold of detection. The image above goes to Ct of 40 (amplification cycles of PCR). The exact RT-PCR Ct values ...


2

With a virus, there are 2 separate things that happen at different speeds, and not at the same time: Live virus comes in contact with your body, and starts replicating, and your body is emitting copies of the live virus in exhalation etc. You are contagious and can spread it to other people at this point. The virus starts damaging the body badly enough ...


1

The symptoms caused by a virus come from a combination of the actual damage done by the virus and side effects of the immune system's response to the virus. Once a virus enters your body there is effectively a race between the reproduction of the virus, and the immune system developing a targeted response to the virus. Also going on in the background, the ...


1

Yes, estimating the prevalence of latent tuberculosis infection using the TST is not trivial. Use only of the TST to define latent tuberculosis infection requires specification of a cut-point for positivity. There is a trade-off between sensitivity and specificity when selecting this cut-point. In prevalence surveys, this is usually >10 mm induration. ...


1

Recent studies have reported that about 80% of people infected with SARS-CoV2 are asymptomatic, it means they are "silent carriers". These patients show no or very mild symptoms. As it is known that viruses need to get into living cells to divide and survive. Same applies with SARS-CoV2, this virus attaches its spike protein present on the outer shell with ...


1

If the person is well, and investigations show no structural defects, then: Early-onset cardiac conduction defects in the absence of structural heart disease should prompt consideration of CCD genetic testing, especially if a positive family history of conduction abnormalities and pacemaker implants is identified. HRS/EHRA Expert Consensus Statement on ...


1

From {1}: In COVID-19, The University of Padua, Veneto Region and the Red Cross tested the populationof Vò, Italy, 3300 people, to establish the natural history of the virus, the transmission dynamicsand categories of risk. "they found >50 of those who tested positive to be asymptomatic” according to Professor Sergio Romagnani. FYI: How can one predict ...


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