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20

One of the primary purposes of corticosteroids is to suppress immune activity and inflammation: that's exactly why they are used in asthma. Of course the immune system has an actual job besides causing nuisance inflammation: fighting infection. For some infections, the harm to the infected person caused by the immune reaction itself is worse than that of ...


7

To answer this question you would need to find the source of the information. I found the study mentioned in the article in the Toronto Star (Chen, et al. 2017); and while studying risks of dementia, Parkinson's disease and multiple sclerosis, with emphasis mine, they said: In this population-based cohort study, we assembled two population-based cohorts ...


7

Asthma can lead to shortage of breath and in severe cases to death by suffocation (called asthmatic asphyxia). Failure of breathing inherently involves that the heart rate stops (called cardiac arrest). A victim who is unresponsive and not breathing normally is in cardiac arrest and requires CPR. European Resuscitation Council, New Guidelines 2015 p. 82 So,...


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In a sudden asthma attack you can take more salbutamol, up to 10 puffs, but you should wait 30 seconds and always shake the inhaler between doses. You can repeat this dose 10 minutes later. NHS.org.uk This would warrant even up to 40 puffs in an hour. The dose of salbutamol administered in severe emergencies can be up to 5mg, and even more as long as the ...


5

This is very dependent on what one defines as a disease. There are people who only count acute conditions and/or infections as "diseases" though I wouldn't have expected a doctor to make this distinction. Under this definition, asthma would not be a disease, but a "chronic condition", for example. I found an interesting article What is a disease which ...


4

There are many factors to consider. The pollution level (and risk) depends on at least the following: typical wind direction during rush hour density of trees between you and the road elevation difference between you and the road presence of a noise wall between you and the road level and type of traffic on the road This page aggregated a large number of ...


4

Yes. There are scientific reasons and treatments involving worms and allergies or other immune system disorders. But the results are not overly conclusive and still understudied. This is based on the so called hygiene hypothesis in immunology. Short version to this: our immune system evolved in a world full of dirt and germs where it had to be quite ...


3

There are long-term medications, those that will get asthma under control: long-acting beta-agonists: bronchodilators, they open the airways leukotriene modifiers: they block the components that cause inflammation mast cell stabilizers: they prevent / reduce the release of chemicals (from your body) that cause inflammation theophylline: is a bronchodilator, ...


3

Drinking cold water having asthma can cause bronchial spasm, a sudden constriction of the muscles in the walls of the bronchioles (tightness in the chest), causing difficulty in breathing. This can be also triggered by Exercise-induced asthma (EIA). The neurotransmitter acetylcholine is known to decrease sympathetic response by slowing the heart rate and ...


3

There are numerous causes and sources of irritation for Asthma exacerbations. Your objective is finding out whether it's irritants (smoke, chemicals, lint, etc) or allergies (pollen, pet dander) that is setting you off. Once you identify the source, you can then take steps to prevent it. It also appears that you've been exposed to poor air quality for a ...


3

Well, PEF (peak expiratory flow) varies thorough the day and it's at its lowest in the morning (which is when patients are usually instructed to take it x3, before their meds), so taking the highest value balances that out a little. Also, we are measuring PEF i.e. maximum speed of expiration, not average speed of expiration ;) And a patient's personal best ...


3

1) How likely is intracranial thrombophlebitis after nasal hair removal? Cavernous sinus thrombosis (Stat Pearls, 2019) after nasal hair removal (or from any cause) seems to be rare but possible: ...annual incidence of cavernous sinus thrombosis might be approximately 0.2 to 1.6 per 100,000 per year. Cavernous sinus thrombosis (CST) is a rare, ...


2

This depends a little on whether the inhaler is a metered-dose inhaler (MDI - aerosol) or dry powder inhaler (DPI). DPI inhalers require adequate inspiratory flow rates. Metered dose inhalers Propellants in MDIs typically make up more than 99% of the delivered dose and are usually hydrofluoroalkanes (HFA). These a gaseous and are usually exhaled. I cannot ...


2

There are apps to help you distinguish Covid-19 versus other diseases so in your question your mention a runny nose which is a rare or infrequent manifestation of covid-19. Shortness of breath is a more advanced symptom than cough whereas in asthma shortness of breath is usual. Furthermore shortness of breath in asthma is due to reversible narrowing of ...


1

The Lancet article you referenced in your question answered the questions you asked. In the trials of high dose corticosteroids used to treat SARS patients Corticosteroids use was: not associated with a difference in 90-day mortality (adjusted odds ratio 0·8, 95% CI 0·5–1·1; p=0·12) associated with delayed clearance of viral RNA from respiratory tract ...


1

Your question can basically be extended to all studies related to statistics. In simple terms you are generally looking for a relationship (e.g. between an increased number of deaths and air pollution levels). Of course finding such a relationship ALONE doesn't tell you anything about cause and effect. Even if you are only looking at deaths from diseases ...


1

Since all of the studies on this specific product seem not only mussel-like but downright fishy when reporting large effects the following is a bit speculative and just assumes that it actually works: Two aspects of action seem possible: EIB is often seen as "even cases of asthma in which exercise appears to be the only trigger of bronchial obstruction (...


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