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First of all, anorgasmia can be either a primary effect caused by depression itself, along with decreased libido. But then it may also be a side-effect of the medication itself, adding to the underlying problem and quite likely decreasing not only libido, erectile function or ability to orgasm but also having a negative effect on compliance with the whole ...


3

This is currently impossible to answer definitely. There is further a difference between 'could become a risk' and 'will likely be a risk'. Only now are even the warnings about the long established connection between SSRI/SNRIs and several forms of sexual dysfunction, including persistent symptoms of discontinuation required to be included on the drug's ...


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First, a correction. ADHD is NOT caused by a dopamine deficiency. It is way more complex than that, but i won't go into detail here. The best treatments for ADHD alter dopamine activity (and they are very effective), but that doesn't mean the cause for ADHD is a dopamine deficiency. So the question is how vortioxetine can help in ADHD. Well, the short ...


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Pharmacology: Inhibits reuptake of serotonin, causes adrenoreceptor subsensitivity, acts as a 5HT2a receptor antagonist and induces significant changes in 5-HT presynaptic receptor adrenoreceptors. Trazodone also significantly blocks histamine (H1) and alpha1-adrenergic receptors. Insomnia (off-label use): Oral: Immediate release: Usual dose: 50 mg to 100 ...


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All Anti-Depressants poop out equally for TR patients. Having just now signed up on this site, it seems a prerequisite to post is that you ought to have at least minimally researched the question, since the site compels ME not to ask for clarification. Either your or Kramer's interpretation (or both) of the phenomenon of tachyphylaxis, especially related to ...


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Its primary action is as NaSSA (a noradrenergic and specific serotonergic antidepressant), not as 5-HT3 inhibitor. If you have a look at e. g. the Wikipedia page (https://en.wikipedia.org/wiki/Mirtazapine#Pharmacodynamics), you will see that nausea is listed as side effect under "discontinuation syndrome", i. e. sudden withdrawal from continuous 5-...


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First of all, you have to be aware that most studies cited are on animals, not humans. Applicability of that data for humans is limited. Second, this molecule is interacting with all kinds of tissues thoughout the entire body. Its pharmacology is quite complicated, but it shows a lot of potential. In general. Its use for depression is not yet among the ...


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The main use of St John's Wort is for depression but there are supposedly other uses (WebMD, n.d.) which may or may not work. The only study I can find on the effectiveness of St John's Wort against mild to moderate depression is Brattström (2009) which you linked to in the comments. The study looked at safety (adverse event frequency) and influence on ...


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