Regarding one of the topics of this subject: Why can’t painkillers be both safe and effective?
It should be duly noted that,
One of the most problematic conditions when using opioids in clinic is the respiratory depression that they can cause
The most common cause of opioid overdose and death is opioid-induced respiratory depression (OIRD)
essentially due ...
By asking a few people I had access to and also searching in some of my reference books like Katzung, Martindale, and finally looking at Newborn Services Drug Protocol, I think I may have reached a conclusion.
Respiratory depression is a possible side effect which could occur in neonates. The drug of choice is Naloxone, although it may not be used in the ...
The only one of those categories that should get the "general" modifier is anesthetic - this is to contrast them with local anesthetics, which are the "numbing agents" you describe.
General anesthesics are agents that cause loss of consciousness. They prevent conscious perception of pain by causing loss of consciousness, rather than ...
According to the U.S. Food and Drug Administration (FDA), 2017:
The GRASE dose for caffeine is established in the Stimulant Final
Monograph as 100-200 mg not more often than every 3-4 hours.
GRASE (generally recognized as safe and effective) is a safety designation the FDA uses for over-the-counter drugs (FDA.gov, Wikipedia).
According to a systematic ...