3

If you think of committing suicide, you can find help here: 1-800-273-8255 No, it is not painful. In fact, opiates and and benzodiazepines are used for assisted suicide and for Palliative medicine. A 1992 nationwide study by one of the authors (G. van der Wal) on drugs used by Dutch general practitioners in euthanasia and physician-assisted ...


2

Yes, it is safe. The mechanism that ibuprofen and paracetamol use are different and don't interact negatively. In fact, the two drugs (medicines) can be used in conjunction for a synergistic effect so that it will provide greater pain relief than either drug alone. With that said, still follow the standard dosing instructions for each drug. That means don't ...


2

I viewed your question in the Biology Stack and I think the answers you received are quite good. I´ll try sum up those long answers in the Biology Stack and present them more clearly. Major factor influencing to the presumed effects of any drug is the first pass effect (Wikipedia). That means that every substance taken orally must absorb from intestine to ...


2

How do painkillers work? When part of your body is injured, special nerve endings send pain messages back to your brain. Painkilling drugs interfere with these messages, either at the site of the injury, in the spinal cord or in the brain itself. Many painkillers are based on one of two naturally occurring drugs: aspirin and opiates. Aspirin uses a ...


2

I had shingles in the last quarter of 2013. It was on the facial and trigeminal nerves. There were times when it felt like someone was boring a hole in my ear with a dull drill bit and pouring 90% isopropyl alcohol on an open wound on my left cheek. It was damn painful.I have been taking gabapentin every since, and I'm not sure NSAIDs would be very helpful. ...


2

Yes, taking too much painkiller can be harmful. Two common painkillers are acetaminophen (brand name Tylenol) and ibuprofen (brand name Advil). They each have different risks. Paracetamol / Acetaminophen The maximum daily dose is 3,000 mg. With the 650 mg extended release pills, the daily limit is just 4 pills. Never consume more than 4,000 mg in a 24 hour ...


1

By asking a few people I had access to and also searching in some of my reference books like Katzung, Martindale, and finally looking at Newborn Services Drug Protocol, I think I may have reached a conclusion. Respiratory depression is a possible side effect which could occur in neonates. The drug of choice is Naloxone, although it may not be used in the ...


1

The only one of those categories that should get the "general" modifier is anesthetic - this is to contrast them with local anesthetics, which are the "numbing agents" you describe. General anesthetics General anesthesics are agents that cause loss of consciousness. They prevent conscious perception of pain by causing loss of consciousness, rather than ...


1

According to the U.S. Food and Drug Administration (FDA), 2017: The GRASE dose for caffeine is established in the Stimulant Final Monograph as 100-200 mg not more often than every 3-4 hours. GRASE (generally recognized as safe and effective) is a safety designation the FDA uses for over-the-counter drugs (FDA.gov, Wikipedia). According to a systematic ...


1

Lidocaine1 is not categorized as a painkiller but as a (local) anesthetic; it can be used during minor procedures where the patient has full awareness by injecting it to the preferred site of action. It inhibits the sodium channels on the nerve endings in the skin. Therefore it provides insensibility of ALL nerve fibers, both causing numbness in the skin ...


1

1. NSAIDs can increase the chance of heart attack or stroke. This risk may be greater if you have heart disease or risk factors (for example, smoking, high blood pressure, high cholesterol, diabetes) for heart disease. However, the risk may also be increased in people who do not have heart disease or those risk factors. Heart problems caused by NSAIDs can ...


1

I am really happy that I found Krill oil. It's an omega 3,6,9 oil made from krill. (a sea creature similar to shrimp but much smaller). It makes this choice the strongest choice in benefits of any fish oil, but no yucky taste if you burp. I can't take NSAIDS anymore, but I found that after a few days of taking krill oil, it works as an anti-inflammatory pain ...


1

At first I want to note arkiaamu's answer is very good. If you also need a shorter answer take this: Naproxene and Aspirine do not only 'directly' relieve pain, they also work antiinflammatory. In many cases the inflammation itself causes pain, so these drugs have different targets to work. See this Tramadol is not antiinflammatory, neither is paracetamol. ...


Only top voted, non community-wiki answers of a minimum length are eligible