**The consumption of food that contains 150% Daily Value or 27 mg of iron *only once* by a healthy person should not result in any side effects.** This is because Tolerable Upper Intake Levels (maximum daily intake unlikely to cause adverse health effects) for iron for individuals age 0-13 is 40 mg and for those age 14 or older is 45 mg ([Office of Dietary Supplements, NIH.gov][1]). **Is acute iron overdose from food (not supplements) in healthy adults possible?** Not likely. According to [Office of Dietary Supplements, NIH.gov][1]: > Adults with normal intestinal function have very little risk of iron > overload from dietary sources of iron. and > acute intakes of more than *20 mg/kg iron from supplements or medicines* > can lead to gastric upset, constipation, nausea, abdominal pain, > vomiting, and faintness. For a 70 kg man, this is 1,400 mg of iron, which is virtually impossible to get from foods even [highest in iron][2]. **What happens with iron consumed in excess of the body needs?** Most of the excessive iron probably won't be absorbed ([AJCN][3]): > If an individual requires more iron, more iron will be mobilized from > body iron stores and there will be an increase in intestinal iron > absorption. However, if the body is iron replete, these processes will > be downregulated. According to [vivo.colostate.edu][4]: > Iron abundance states: iron within the enterocyte [intestinal lining > cell] is trapped by incorporation into ferritin and hence, not > transported into blood. When the enterocyte dies and is shed, this > iron is lost. **Would a single ingestion of 150% Daily Value of iron be harmful for a person with hemochromatosis?** Not likely. According to the article [The myths and realities of hemochromatosis (Canadian Journal of Gastroenterology)][5]: > Although dietary iron is the source of excess iron in hemochromatosis, > a decrease in dietary iron has not been shown to decrease iron stores > in hemochromatosis. [1]: https://ods.od.nih.gov/factsheets/Iron-HealthProfessional/ [2]: https://nutritiondata.self.com/foods-000119000000000000000-w.html [3]: https://academic.oup.com/ajcn/article/106/suppl_6/1559S/4823167 [4]: http://www.vivo.colostate.edu/hbooks/pathphys/digestion/smallgut/absorb_minerals.html [5]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657669/